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• W2149437524 endingPage "74" @default.
• W2149437524 startingPage "60" @default.
• W2149437524 abstract "Complex chemical processes termed non-enzymic glycation that operate in vivo and similar chemical interactions between sugars and proteins that occur during thermal processing of food (known as the Maillard reaction) are one of the interesting examples of a potentially-harmful interaction between nutrition and disease. Non-enzymic glycation comprises a series of reactions between sugars, alpha-oxoaldehydes and other sugar derivatives and amino groups of amino acids, peptides and proteins leading to the formation of heterogeneous moieties collectively termed advanced glycation end products (AGE). AGE possess a wide range of chemical and biological properties and play a role in diabetes-related pathology as well as in several other diseases. Diabetes is, nevertheless, of particular interest for several reasons: (1) chronic hyperglycaemia provides the substrates for extracellular glycation as well as intracellular glycation; (2) hyperglycaemia-induced oxidative stress accelerates AGE formation in the process of glycoxidation; (3) AGE-modified proteins are subject to rapid intracellular proteolytic degradation releasing free AGE adducts into the circulation where they can bind to several pro-inflammatory receptors, especially receptor of AGE; (4) kidneys, which are principally involved in the excretion of free AGE adducts, might be damaged by diabetic nephropathy, which further enhances AGE toxicity because of diminished AGE clearance. Increased dietary intake of AGE in highly-processed foods may represent an additional exogenous metabolic burden in addition to AGE already present endogenously in subjects with diabetes. Finally, inter-individual genetic and functional variability in genes encoding enzymes and receptors involved in either the formation or the degradation of AGE could have important pathogenic, nutrigenomic and nutrigenetic consequences." @default.
• W2149437524 created "2016-06-24" @default.
• W2149437524 creator A5038317007 @default.
• W2149437524 date "2008-01-30" @default.
• W2149437524 modified "2023-10-16" @default.
• W2149437524 title "Diabetic threesome (hyperglycaemia, renal function and nutrition) and advanced glycation end products: evidence for the multiple-hit agent?" @default.
• W2149437524 cites W12609457 @default.
• W2149437524 cites W1487088539 @default.
• W2149437524 cites W1503258737 @default.
• W2149437524 cites W1529592271 @default.
• W2149437524 cites W1547902391 @default.
• W2149437524 cites W1565131882 @default.
• W2149437524 cites W1572011530 @default.
• W2149437524 cites W1575563617 @default.
• W2149437524 cites W1840001967 @default.
• W2149437524 cites W1964015869 @default.
• W2149437524 cites W1965591294 @default.
• W2149437524 cites W1966603392 @default.
• W2149437524 cites W1967682390 @default.
• W2149437524 cites W1967945049 @default.
• W2149437524 cites W1968003131 @default.
• W2149437524 cites W1968106500 @default.
• W2149437524 cites W1968233853 @default.
• W2149437524 cites W1968569587 @default.
• W2149437524 cites W1970843729 @default.
• W2149437524 cites W1971209988 @default.
• W2149437524 cites W1976611127 @default.
• W2149437524 cites W1978718183 @default.
• W2149437524 cites W1981133477 @default.
• W2149437524 cites W1982383229 @default.
• W2149437524 cites W1985236743 @default.
• W2149437524 cites W1985417086 @default.
• W2149437524 cites W1986059252 @default.
• W2149437524 cites W1986474765 @default.
• W2149437524 cites W1988614821 @default.
• W2149437524 cites W1990365963 @default.
• W2149437524 cites W1991683975 @default.
• W2149437524 cites W1992484293 @default.
• W2149437524 cites W1992850373 @default.
• W2149437524 cites W1993381730 @default.
• W2149437524 cites W1994051814 @default.
• W2149437524 cites W1996478420 @default.
• W2149437524 cites W1996694657 @default.
• W2149437524 cites W1997604729 @default.
• W2149437524 cites W1998277604 @default.
• W2149437524 cites W2000782226 @default.
• W2149437524 cites W2002616153 @default.
• W2149437524 cites W2002705517 @default.
• W2149437524 cites W2004482266 @default.
• W2149437524 cites W2004771015 @default.
• W2149437524 cites W2005640704 @default.
• W2149437524 cites W2006193286 @default.
• W2149437524 cites W2007728464 @default.
• W2149437524 cites W2011080190 @default.
• W2149437524 cites W2011443409 @default.
• W2149437524 cites W2011955651 @default.
• W2149437524 cites W2013180282 @default.
• W2149437524 cites W2013477631 @default.
• W2149437524 cites W2013730613 @default.
• W2149437524 cites W2017620761 @default.
• W2149437524 cites W2021001924 @default.
• W2149437524 cites W2021242983 @default.
• W2149437524 cites W2021289068 @default.
• W2149437524 cites W2021346724 @default.
• W2149437524 cites W2021458914 @default.
• W2149437524 cites W2021995513 @default.
• W2149437524 cites W2025189315 @default.
• W2149437524 cites W2027914534 @default.
• W2149437524 cites W2031215872 @default.
• W2149437524 cites W2031484324 @default.
• W2149437524 cites W2032037180 @default.
• W2149437524 cites W2033274423 @default.
• W2149437524 cites W2033816859 @default.
• W2149437524 cites W2034138847 @default.
• W2149437524 cites W2035409564 @default.
• W2149437524 cites W2036291252 @default.
• W2149437524 cites W2036685670 @default.
• W2149437524 cites W2041012283 @default.
• W2149437524 cites W2043294107 @default.
• W2149437524 cites W2043867801 @default.
• W2149437524 cites W2044437167 @default.
• W2149437524 cites W2046828317 @default.
• W2149437524 cites W2048261702 @default.
• W2149437524 cites W2049167261 @default.
• W2149437524 cites W2049426625 @default.
• W2149437524 cites W2050157597 @default.
• W2149437524 cites W2051581102 @default.
• W2149437524 cites W2051612655 @default.
• W2149437524 cites W2052954861 @default.
• W2149437524 cites W2054083698 @default.
• W2149437524 cites W2054646177 @default.
• W2149437524 cites W2056952939 @default.
• W2149437524 cites W2057491765 @default.
• W2149437524 cites W2057667692 @default.
• W2149437524 cites W2057961754 @default.
• W2149437524 cites W2062273929 @default.
• W2149437524 cites W2063245219 @default.
• W2149437524 cites W2071675524 @default.

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