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- W2149454872 abstract "Rat cerebral cortex slices labeled with 3H-noradrenaline (NA) were superfused and 3H-NA release was induced with 20 mM K+. The release of 3H-NA was not affected by DA (1 micro M), but was inhibited by the 2-aminotetralins, 5,6-ADTN and N,N-dipropyl-5,6-ADTN (at a concentration of 1 micro M) by about 27% and 65%, respectively. The inhibitory effect of N,N-dipropyl-5,6-ADTN was concentration-dependent (3 x 10(-8) to 3 x 10(-7) M) and was antagonized by phentolamine but not by fluphenazine. The data indicate that, in addition to activating dopamine receptors, N,N-dipropyl-5,6-ADTN stimulates presynaptic alpha-NA receptors." @default.
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- W2149454872 date "1980-10-01" @default.
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- W2149454872 title "Activation of presynaptic α-noradrenaline receptors in rat brain by the potent dopamine-mimetic N, N-dipropyl-5,6-ADTN" @default.
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- W2149454872 doi "https://doi.org/10.1016/0014-2999(80)90024-2" @default.
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