Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149455943> ?p ?o ?g. }
- W2149455943 endingPage "9" @default.
- W2149455943 startingPage "1" @default.
- W2149455943 abstract "Purple sweet potato color (PSPC), a naturally occurring anthocyanin, has a powerful antioxidant activity in vitro and in vivo. This study explores whether PSPC has the neuroprotective effect on the aging mouse brain induced by D-galactose (D-gal). The mice administrated with PSPC (100 mg/kg.day, 4 weeks, from 9th week) via oral gavage showed significantly improved behavior performance in the open field and passive avoidance test compared with D-gal-treated mice (500 mg/kg.day, 8 weeks). We further investigate the mechanism involved in neuroprotective effects of PSPC on mouse brain. Interestingly, we found, PSPC decreased the expression level of glial fibrillary acidic protein (GFAP), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2), inhibited nuclear translocation of nuclear factor-kappaB (NF-<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>κ</mml:mi></mml:math>B), increased the activity of copper/zinc superoxide dismutase (Cu/Zn-SOD) and catalase (CAT), and reduced the content of malondialdehyde (MDA), respectively. Our data suggested that PSPC attenuated D-gal-induced cognitive impairment partly via enhancing the antioxidant and anti-inflammatory capacity." @default.
- W2149455943 created "2016-06-24" @default.
- W2149455943 creator A5012677271 @default.
- W2149455943 creator A5015425896 @default.
- W2149455943 creator A5032198140 @default.
- W2149455943 creator A5034732631 @default.
- W2149455943 creator A5036101767 @default.
- W2149455943 creator A5057575317 @default.
- W2149455943 creator A5059263184 @default.
- W2149455943 creator A5063749738 @default.
- W2149455943 creator A5071796379 @default.
- W2149455943 creator A5077911514 @default.
- W2149455943 creator A5081228075 @default.
- W2149455943 date "2009-01-01" @default.
- W2149455943 modified "2023-10-17" @default.
- W2149455943 title "Purple Sweet Potato Color Ameliorates Cognition Deficits and Attenuates Oxidative Damage and Inflammation in Aging Mouse Brain Induced by D-Galactose" @default.
- W2149455943 cites W191793640 @default.
- W2149455943 cites W1970949541 @default.
- W2149455943 cites W1972831287 @default.
- W2149455943 cites W1978572904 @default.
- W2149455943 cites W1981024134 @default.
- W2149455943 cites W1983752276 @default.
- W2149455943 cites W1992658935 @default.
- W2149455943 cites W1995994766 @default.
- W2149455943 cites W2025983417 @default.
- W2149455943 cites W2030120755 @default.
- W2149455943 cites W2030886910 @default.
- W2149455943 cites W2034003832 @default.
- W2149455943 cites W2034337512 @default.
- W2149455943 cites W2035335881 @default.
- W2149455943 cites W2036691113 @default.
- W2149455943 cites W2042339318 @default.
- W2149455943 cites W2043158494 @default.
- W2149455943 cites W2043519828 @default.
- W2149455943 cites W2044480651 @default.
- W2149455943 cites W2045523034 @default.
- W2149455943 cites W2050996284 @default.
- W2149455943 cites W2052205724 @default.
- W2149455943 cites W2052310155 @default.
- W2149455943 cites W2053054955 @default.
- W2149455943 cites W2055555774 @default.
- W2149455943 cites W2056170209 @default.
- W2149455943 cites W2057693347 @default.
- W2149455943 cites W2062621164 @default.
- W2149455943 cites W2068934649 @default.
- W2149455943 cites W2073589082 @default.
- W2149455943 cites W2078283218 @default.
- W2149455943 cites W2080960191 @default.
- W2149455943 cites W2082137621 @default.
- W2149455943 cites W2083672308 @default.
- W2149455943 cites W2085974525 @default.
- W2149455943 cites W2086418897 @default.
- W2149455943 cites W2100577029 @default.
- W2149455943 cites W2109107050 @default.
- W2149455943 cites W2123197349 @default.
- W2149455943 cites W2129227455 @default.
- W2149455943 cites W2129366560 @default.
- W2149455943 cites W2144304323 @default.
- W2149455943 cites W2149748813 @default.
- W2149455943 cites W2154762061 @default.
- W2149455943 cites W2159305277 @default.
- W2149455943 cites W4251538268 @default.
- W2149455943 cites W76769348 @default.
- W2149455943 doi "https://doi.org/10.1155/2009/564737" @default.
- W2149455943 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2766785" @default.
- W2149455943 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19865488" @default.
- W2149455943 hasPublicationYear "2009" @default.
- W2149455943 type Work @default.
- W2149455943 sameAs 2149455943 @default.
- W2149455943 citedByCount "76" @default.
- W2149455943 countsByYear W21494559432012 @default.
- W2149455943 countsByYear W21494559432013 @default.
- W2149455943 countsByYear W21494559432014 @default.
- W2149455943 countsByYear W21494559432015 @default.
- W2149455943 countsByYear W21494559432016 @default.
- W2149455943 countsByYear W21494559432017 @default.
- W2149455943 countsByYear W21494559432018 @default.
- W2149455943 countsByYear W21494559432019 @default.
- W2149455943 countsByYear W21494559432020 @default.
- W2149455943 countsByYear W21494559432021 @default.
- W2149455943 countsByYear W21494559432022 @default.
- W2149455943 countsByYear W21494559432023 @default.
- W2149455943 crossrefType "journal-article" @default.
- W2149455943 hasAuthorship W2149455943A5012677271 @default.
- W2149455943 hasAuthorship W2149455943A5015425896 @default.
- W2149455943 hasAuthorship W2149455943A5032198140 @default.
- W2149455943 hasAuthorship W2149455943A5034732631 @default.
- W2149455943 hasAuthorship W2149455943A5036101767 @default.
- W2149455943 hasAuthorship W2149455943A5057575317 @default.
- W2149455943 hasAuthorship W2149455943A5059263184 @default.
- W2149455943 hasAuthorship W2149455943A5063749738 @default.
- W2149455943 hasAuthorship W2149455943A5071796379 @default.
- W2149455943 hasAuthorship W2149455943A5077911514 @default.
- W2149455943 hasAuthorship W2149455943A5081228075 @default.
- W2149455943 hasBestOaLocation W21494559431 @default.
- W2149455943 hasConcept C126322002 @default.
- W2149455943 hasConcept C178790620 @default.
- W2149455943 hasConcept C181199279 @default.