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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149477089> ?p ?o ?g. }

• W2149477089 endingPage "9" @default.
• W2149477089 startingPage "2013" @default.
• W2149477089 abstract "Vascular endothelial growth factor (VEGF) increased the level of ETS1 mRNA in human umbilical vein endothelial cells (HUVEC) and human lung microvascular endothelial cells (HMVEC-L) over 5-fold. Protein levels were shown to increase concordantly. VEGF was also found to stimulate the invasiveness of endothelial cells as measured by migration through Matrigel- or gelatin-coated membranes. The VEGF-induced invasiveness was inhibited by ETS1 antisense oligonucleotides but not by a sense control. In addition, the ETS1 antisense oligonucleotides reduced the levels of ETS1 and urokinase-type plasminogen activator mRNAs. The antisense oligonucleotides directed against the ETS1 gene thus altered a cellular property of endothelial cells that is correlated with the ability of the cells to migrate through basement membranes. Together, these observations demonstrate a direct role for the ETS1 gene in angiogenesis." @default.
• W2149477089 created "2016-06-24" @default.
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• W2149477089 date "1997-05-15" @default.
• W2149477089 modified "2023-10-16" @default.
• W2149477089 title "Inhibition of vascular endothelial growth factor-induced endothelial cell migration by ETS1 antisense oligonucleotides." @default.
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• W2149477089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9157999" @default.
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