FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149488552> ?p ?o ?g. }

• W2149488552 endingPage "2902" @default.
• W2149488552 startingPage "2902" @default.
• W2149488552 abstract "Endotoxin, also known as lipopolysaccharide (LPS), is able to induce a strong immune response on its internalization into mammalian cells. To date, aptamer-based biosensors for LPS detection have been rarely reported. This work describes a new signal-on electrochemical aptasensor for the ultrasensitive detection of LPS by combining the three-way DNA hybridization process and nanotechnology-based amplification. With the help of DNA1 (associated with the concentration of target LPS), the capture probe hybridizes with DNA1 and the assistant probe to open its hairpin structure and form a ternary Y junction structure. The DNA1 can be released from the structure in the presence of nicking endonuclease to initiate the next hybridization process. Then a great deal of cleaved capture probe produced in the cyclic process can bind with DNA2-nanocomposite, which contains the electroactive toluidine blue (Tb) with the amplification materials graphene (Gra) and gold nanoparticles (AuNPs). Thus, an enhanced electrochemical signal can be easily read out. With the cascade signal amplification, this newly designed protocol provides an ultrasensitive electrochemical detection of LPS down to the femtogram level (8.7 fg mL(-1)) with a linear range of 6 orders of magnitude (from 10 fg mL(-1) to 50 ng mL(-1)). Moreover, the high sensitivity and specificity make this method versatile for the detection of other biomolecules by changing the corresponding sequences of the capture probe and the assistant probe." @default.
• W2149488552 created "2016-06-24" @default.
• W2149488552 creator A5050065934 @default.
• W2149488552 creator A5057795872 @default.
• W2149488552 creator A5075456604 @default.
• W2149488552 creator A5081757083 @default.
• W2149488552 date "2014-01-01" @default.
• W2149488552 modified "2023-10-18" @default.
• W2149488552 title "A signal-on electrochemical aptasensor for ultrasensitive detection of endotoxin using three-way DNA junction-aided enzymatic recycling and graphene nanohybrid for amplification" @default.
• W2149488552 cites W1481001832 @default.
• W2149488552 cites W1895371070 @default.
• W2149488552 cites W1936399524 @default.
• W2149488552 cites W1970671138 @default.
• W2149488552 cites W1997005329 @default.
• W2149488552 cites W1997097517 @default.
• W2149488552 cites W1997686479 @default.
• W2149488552 cites W1999705018 @default.
• W2149488552 cites W2018924940 @default.
• W2149488552 cites W2021484192 @default.
• W2149488552 cites W2026241422 @default.
• W2149488552 cites W2036946508 @default.
• W2149488552 cites W2043381968 @default.
• W2149488552 cites W2044440155 @default.
• W2149488552 cites W2046000595 @default.
• W2149488552 cites W2056815766 @default.
• W2149488552 cites W2057317821 @default.
• W2149488552 cites W2058076784 @default.
• W2149488552 cites W2062277062 @default.
• W2149488552 cites W2063517721 @default.
• W2149488552 cites W2069751695 @default.
• W2149488552 cites W2071159951 @default.
• W2149488552 cites W2071621874 @default.
• W2149488552 cites W2077013529 @default.
• W2149488552 cites W2080591407 @default.
• W2149488552 cites W2081450425 @default.
• W2149488552 cites W2085249269 @default.
• W2149488552 cites W2093088906 @default.
• W2149488552 cites W2098286922 @default.
• W2149488552 cites W2101977779 @default.
• W2149488552 cites W2104525153 @default.
• W2149488552 cites W2113828544 @default.
• W2149488552 cites W2166891317 @default.
• W2149488552 cites W2170195185 @default.
• W2149488552 cites W2171086443 @default.
• W2149488552 cites W2316994040 @default.
• W2149488552 cites W2328547378 @default.
• W2149488552 cites W2950996370 @default.
• W2149488552 doi "https://doi.org/10.1039/c3nr05930h" @default.
• W2149488552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24477782" @default.
• W2149488552 hasPublicationYear "2014" @default.
• W2149488552 type Work @default.
• W2149488552 sameAs 2149488552 @default.
• W2149488552 citedByCount "90" @default.
• W2149488552 countsByYear W21494885522014 @default.
• W2149488552 countsByYear W21494885522015 @default.
• W2149488552 countsByYear W21494885522016 @default.
• W2149488552 countsByYear W21494885522017 @default.
• W2149488552 countsByYear W21494885522018 @default.
• W2149488552 countsByYear W21494885522019 @default.
• W2149488552 countsByYear W21494885522020 @default.
• W2149488552 countsByYear W21494885522021 @default.
• W2149488552 countsByYear W21494885522022 @default.
• W2149488552 countsByYear W21494885522023 @default.
• W2149488552 crossrefType "journal-article" @default.
• W2149488552 hasAuthorship W2149488552A5050065934 @default.
• W2149488552 hasAuthorship W2149488552A5057795872 @default.
• W2149488552 hasAuthorship W2149488552A5075456604 @default.
• W2149488552 hasAuthorship W2149488552A5081757083 @default.
• W2149488552 hasConcept C119128265 @default.
• W2149488552 hasConcept C128972844 @default.
• W2149488552 hasConcept C153911025 @default.
• W2149488552 hasConcept C160756335 @default.
• W2149488552 hasConcept C171250308 @default.
• W2149488552 hasConcept C185592680 @default.
• W2149488552 hasConcept C192562407 @default.
• W2149488552 hasConcept C21951064 @default.
• W2149488552 hasConcept C30080830 @default.
• W2149488552 hasConcept C43617362 @default.
• W2149488552 hasConcept C49853544 @default.
• W2149488552 hasConcept C86803240 @default.
• W2149488552 hasConceptScore W2149488552C119128265 @default.
• W2149488552 hasConceptScore W2149488552C128972844 @default.
• W2149488552 hasConceptScore W2149488552C153911025 @default.
• W2149488552 hasConceptScore W2149488552C160756335 @default.
• W2149488552 hasConceptScore W2149488552C171250308 @default.
• W2149488552 hasConceptScore W2149488552C185592680 @default.
• W2149488552 hasConceptScore W2149488552C192562407 @default.
• W2149488552 hasConceptScore W2149488552C21951064 @default.
• W2149488552 hasConceptScore W2149488552C30080830 @default.
• W2149488552 hasConceptScore W2149488552C43617362 @default.
• W2149488552 hasConceptScore W2149488552C49853544 @default.
• W2149488552 hasConceptScore W2149488552C86803240 @default.
• W2149488552 hasIssue "5" @default.
• W2149488552 hasLocation W21494885521 @default.
• W2149488552 hasLocation W21494885522 @default.
• W2149488552 hasOpenAccess W2149488552 @default.
• W2149488552 hasPrimaryLocation W21494885521 @default.
• W2149488552 hasRelatedWork W2070482770 @default.

• next