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• W2149492883 abstract "Subthalamic nucleus (STN) stimulation improves motor disability and quality of life in patients with advanced Parkinson's disease (PD). Short-term mortality is low, but little is known about long-term mortality. We assessed mortality and causes of death in 171 consecutive PD patients treated by STN stimulation. Surgery was performed after a median lagtime of 13 years from PD onset at a median age of 57 years. The median follow-up after surgery was 41 months. Sixteen patients died 8 to 83 months after neurosurgery. Poorer cognitive function was the only predictive factor for mortality (standardized mortality ratio = 2.9; 95% confidence interval [CI], 1.6–4.7; P < 0.0001). Based on a historical comparison of 118 operated patients with 39 nonoperated patients from a different population, survival among operated patients was not better (hazard ratio = 1.2; 95% CI, 0.7–2.1). © 2006 Movement Disorder Society" @default.
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• W2149492883 date "2007-01-01" @default.
• W2149492883 modified "2023-10-17" @default.
• W2149492883 title "Mortality in patients with Parkinson's disease treated by stimulation of the subthalamic nucleus" @default.
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• W2149492883 doi "https://doi.org/10.1002/mds.21264" @default.
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