Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149526866> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2149526866 endingPage "418" @default.
- W2149526866 startingPage "413" @default.
- W2149526866 abstract "Esophageal atresia (EA) with or without tracheo-esophageal fistula (TEF) is a relatively rare congenital anomaly. Despite the advances in the management techniques and neonatal intensive care, esophageal dysmotility remains a very common problem following EA/TEF repair. Our current study aimed to describe the most significant ultrastructural changes of the smooth muscle cells (SMCs) trying to highlight some of the underlying mechanisms of esophageal dysmotility following EA/TEF repair. Twenty-three biopsies were obtained from the tip of the lower esophageal pouch (LEP) of 23 patients during primary repair of EA/TEF. Light microscopic examination was performed with hematoxylin and eosin (HE), and Van Gieson's stains. Ultrastructural examination was done using transmission electron microscopy (TEM). Histopathological examination showed distortion of smooth muscle layer and deposition of an abundant amount of fibrous tissue in-between smooth muscles. Using TEM, SMCs exhibited loss of the cell-to-cell adhesion, mitochondrial vacuolation, formation of myelin figures, and apoptotic fragmentation. There were also plasmalemmal projections and formation of ghost bodies. Interestingly, SMCs were found extending pseudopodia-like projections around adjacent collagen fibers. Engulfed collagen fibers by SMCs underwent degradation within autophagic vacuoles. Degeneration of SMCs and deposition of abundant extracellular collagen fibers are prominent pathological changes in LEP of EA/TEF. These changes might contribute to the pathogenesis of esophageal dysmotility in patients who have survived EA/TEF." @default.
- W2149526866 created "2016-06-24" @default.
- W2149526866 creator A5000241752 @default.
- W2149526866 creator A5005649240 @default.
- W2149526866 creator A5005852992 @default.
- W2149526866 creator A5033306835 @default.
- W2149526866 creator A5087780687 @default.
- W2149526866 creator A5089543788 @default.
- W2149526866 date "2015-08-17" @default.
- W2149526866 modified "2023-09-27" @default.
- W2149526866 title "Ultrastructural Changes of the Smooth Muscle in Esophageal Atresia" @default.
- W2149526866 cites W1961476630 @default.
- W2149526866 cites W1966680459 @default.
- W2149526866 cites W1968801552 @default.
- W2149526866 cites W1973058380 @default.
- W2149526866 cites W1981667437 @default.
- W2149526866 cites W1985024383 @default.
- W2149526866 cites W1993352660 @default.
- W2149526866 cites W2009463011 @default.
- W2149526866 cites W2014456661 @default.
- W2149526866 cites W2025718725 @default.
- W2149526866 cites W2029931185 @default.
- W2149526866 cites W2030045839 @default.
- W2149526866 cites W2065388726 @default.
- W2149526866 cites W2086080463 @default.
- W2149526866 cites W2099704898 @default.
- W2149526866 cites W2100311780 @default.
- W2149526866 cites W2124417606 @default.
- W2149526866 cites W2136015709 @default.
- W2149526866 cites W2145274299 @default.
- W2149526866 cites W2151272527 @default.
- W2149526866 cites W2317769146 @default.
- W2149526866 cites W1790473977 @default.
- W2149526866 doi "https://doi.org/10.3109/01913123.2015.1066913" @default.
- W2149526866 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26548437" @default.
- W2149526866 hasPublicationYear "2015" @default.
- W2149526866 type Work @default.
- W2149526866 sameAs 2149526866 @default.
- W2149526866 citedByCount "3" @default.
- W2149526866 countsByYear W21495268662017 @default.
- W2149526866 crossrefType "journal-article" @default.
- W2149526866 hasAuthorship W2149526866A5000241752 @default.
- W2149526866 hasAuthorship W2149526866A5005649240 @default.
- W2149526866 hasAuthorship W2149526866A5005852992 @default.
- W2149526866 hasAuthorship W2149526866A5033306835 @default.
- W2149526866 hasAuthorship W2149526866A5087780687 @default.
- W2149526866 hasAuthorship W2149526866A5089543788 @default.
- W2149526866 hasConcept C105702510 @default.
- W2149526866 hasConcept C125473707 @default.
- W2149526866 hasConcept C142724271 @default.
- W2149526866 hasConcept C147075424 @default.
- W2149526866 hasConcept C2777229141 @default.
- W2149526866 hasConcept C2781149206 @default.
- W2149526866 hasConcept C64837602 @default.
- W2149526866 hasConcept C71924100 @default.
- W2149526866 hasConcept C74864618 @default.
- W2149526866 hasConcept C86803240 @default.
- W2149526866 hasConcept C87555872 @default.
- W2149526866 hasConceptScore W2149526866C105702510 @default.
- W2149526866 hasConceptScore W2149526866C125473707 @default.
- W2149526866 hasConceptScore W2149526866C142724271 @default.
- W2149526866 hasConceptScore W2149526866C147075424 @default.
- W2149526866 hasConceptScore W2149526866C2777229141 @default.
- W2149526866 hasConceptScore W2149526866C2781149206 @default.
- W2149526866 hasConceptScore W2149526866C64837602 @default.
- W2149526866 hasConceptScore W2149526866C71924100 @default.
- W2149526866 hasConceptScore W2149526866C74864618 @default.
- W2149526866 hasConceptScore W2149526866C86803240 @default.
- W2149526866 hasConceptScore W2149526866C87555872 @default.
- W2149526866 hasIssue "6" @default.
- W2149526866 hasLocation W21495268661 @default.
- W2149526866 hasLocation W21495268662 @default.
- W2149526866 hasOpenAccess W2149526866 @default.
- W2149526866 hasPrimaryLocation W21495268661 @default.
- W2149526866 hasRelatedWork W1984039260 @default.
- W2149526866 hasRelatedWork W2149526866 @default.
- W2149526866 hasRelatedWork W2263986606 @default.
- W2149526866 hasRelatedWork W2378358762 @default.
- W2149526866 hasRelatedWork W2413921471 @default.
- W2149526866 hasRelatedWork W2441037178 @default.
- W2149526866 hasRelatedWork W4322725012 @default.
- W2149526866 hasRelatedWork W4380366509 @default.
- W2149526866 hasRelatedWork W2566721148 @default.
- W2149526866 hasRelatedWork W2601494431 @default.
- W2149526866 hasVolume "39" @default.
- W2149526866 isParatext "false" @default.
- W2149526866 isRetracted "false" @default.
- W2149526866 magId "2149526866" @default.
- W2149526866 workType "article" @default.