FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149584710> ?p ?o ?g. }

• W2149584710 endingPage "211" @default.
• W2149584710 startingPage "201" @default.
• W2149584710 abstract "Polymorphisms in genes involved in DNA repair, steroid hormone biosynthesis/metabolism/signaling, folate metabolism as well as cell growth are prime candidates for possible associations with breast and ovarian cancer risk in women with an inherited predisposition. We investigated 29 polymorphisms in 20 genes encoding key proteins of the above four biological pathways for their breast and ovarian cancer risk modifying effect in Polish women harboring BRCA1 founder mutations. Of the analyzed genes, ERCC2, XRCC1, XRCC2, XRCC3 and Lig4 participate in DNA repair, TP53 in cell cycle check point control, AIB1, AR, COMT, CYP11A1, CYP17A1, CYP19A1, HSD17 and PGR in steroid hormone biosynthesis/metabolism/signaling, TYMS in folate metabolism and HER2, IL6, LRP1, TGFB and TGFBR1 affect cell growth. Using validated methods, we genotyped 319 breast cancer cases, 146 ovarian cancer cases and 290 unaffected controls, all of whom harbored one of three causative mutations in BRCA1. Our results revealed no association of any of the investigated polymorphisms with BRCA1-associated breast or ovarian cancer risk. Thus, it appears that these polymorphisms do not influence disease risk in Polish women carrying one of the three common BRCA1 founder mutations." @default.
• W2149584710 created "2016-06-24" @default.
• W2149584710 creator A5003294074 @default.
• W2149584710 creator A5016817677 @default.
• W2149584710 creator A5024915140 @default.
• W2149584710 creator A5026014942 @default.
• W2149584710 creator A5026033317 @default.
• W2149584710 creator A5044191947 @default.
• W2149584710 creator A5045766478 @default.
• W2149584710 creator A5056748204 @default.
• W2149584710 creator A5057994815 @default.
• W2149584710 creator A5065070297 @default.
• W2149584710 creator A5066102808 @default.
• W2149584710 creator A5070492310 @default.
• W2149584710 creator A5080472244 @default.
• W2149584710 creator A5090925673 @default.
• W2149584710 date "2009-04-10" @default.
• W2149584710 modified "2023-10-16" @default.
• W2149584710 title "BRCA1-associated breast and ovarian cancer risks in Poland: no association with commonly studied polymorphisms" @default.
• W2149584710 cites W1242630251 @default.
• W2149584710 cites W1897413751 @default.
• W2149584710 cites W1969900561 @default.
• W2149584710 cites W1972241427 @default.
• W2149584710 cites W1973550734 @default.
• W2149584710 cites W1979368669 @default.
• W2149584710 cites W1979892206 @default.
• W2149584710 cites W1983936215 @default.
• W2149584710 cites W1988478139 @default.
• W2149584710 cites W1992426043 @default.
• W2149584710 cites W2009897234 @default.
• W2149584710 cites W2037546651 @default.
• W2149584710 cites W2045667568 @default.
• W2149584710 cites W2064347825 @default.
• W2149584710 cites W2077923251 @default.
• W2149584710 cites W2078837019 @default.
• W2149584710 cites W2079506269 @default.
• W2149584710 cites W2080814591 @default.
• W2149584710 cites W2092913524 @default.
• W2149584710 cites W2094609159 @default.
• W2149584710 cites W2100816669 @default.
• W2149584710 cites W2103970959 @default.
• W2149584710 cites W2105850755 @default.
• W2149584710 cites W2105956205 @default.
• W2149584710 cites W2107180558 @default.
• W2149584710 cites W2117324289 @default.
• W2149584710 cites W2117701878 @default.
• W2149584710 cites W2127551036 @default.
• W2149584710 cites W2128946284 @default.
• W2149584710 cites W2131375425 @default.
• W2149584710 cites W2143661312 @default.
• W2149584710 cites W2150111967 @default.
• W2149584710 cites W2151271083 @default.
• W2149584710 cites W2152768572 @default.
• W2149584710 cites W2157794462 @default.
• W2149584710 cites W2160285392 @default.
• W2149584710 doi "https://doi.org/10.1007/s10549-009-0390-5" @default.
• W2149584710 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19360465" @default.
• W2149584710 hasPublicationYear "2009" @default.
• W2149584710 type Work @default.
• W2149584710 sameAs 2149584710 @default.
• W2149584710 citedByCount "72" @default.
• W2149584710 countsByYear W21495847102012 @default.
• W2149584710 countsByYear W21495847102013 @default.
• W2149584710 countsByYear W21495847102014 @default.
• W2149584710 countsByYear W21495847102015 @default.
• W2149584710 countsByYear W21495847102016 @default.
• W2149584710 countsByYear W21495847102017 @default.
• W2149584710 countsByYear W21495847102018 @default.
• W2149584710 countsByYear W21495847102020 @default.
• W2149584710 countsByYear W21495847102021 @default.
• W2149584710 countsByYear W21495847102022 @default.
• W2149584710 countsByYear W21495847102023 @default.
• W2149584710 crossrefType "journal-article" @default.
• W2149584710 hasAuthorship W2149584710A5003294074 @default.
• W2149584710 hasAuthorship W2149584710A5016817677 @default.
• W2149584710 hasAuthorship W2149584710A5024915140 @default.
• W2149584710 hasAuthorship W2149584710A5026014942 @default.
• W2149584710 hasAuthorship W2149584710A5026033317 @default.
• W2149584710 hasAuthorship W2149584710A5044191947 @default.
• W2149584710 hasAuthorship W2149584710A5045766478 @default.
• W2149584710 hasAuthorship W2149584710A5056748204 @default.
• W2149584710 hasAuthorship W2149584710A5057994815 @default.
• W2149584710 hasAuthorship W2149584710A5065070297 @default.
• W2149584710 hasAuthorship W2149584710A5066102808 @default.
• W2149584710 hasAuthorship W2149584710A5070492310 @default.
• W2149584710 hasAuthorship W2149584710A5080472244 @default.
• W2149584710 hasAuthorship W2149584710A5090925673 @default.
• W2149584710 hasBestOaLocation W21495847102 @default.
• W2149584710 hasConcept C104317684 @default.
• W2149584710 hasConcept C121608353 @default.
• W2149584710 hasConcept C126322002 @default.
• W2149584710 hasConcept C134018914 @default.
• W2149584710 hasConcept C134935766 @default.
• W2149584710 hasConcept C135763542 @default.
• W2149584710 hasConcept C143998085 @default.
• W2149584710 hasConcept C153209595 @default.
• W2149584710 hasConcept C2776999993 @default.
• W2149584710 hasConcept C2779755913 @default.

• next