FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149590941> ?p ?o ?g. }

• W2149590941 endingPage "3048" @default.
• W2149590941 startingPage "3043" @default.
• W2149590941 abstract "A novel indole series of PGD2 receptor (DP receptor) antagonists is presented. Optimization of this series led to the identification of potent and selective DP receptor antagonists. In particular, antagonists 35 and 36 were identified with Ki values of 2.6 and 1.8 nM, respectively. These two antagonists are also potent in a DP functional assay where they inhibit the PGD2 induced cAMP production in platelet rich plasma with IC50 values of 7.9 and 8.6 nM, respectively. The structure–activity relationships of this indole series of DP receptor antagonists will also be discussed." @default.
• W2149590941 created "2016-06-24" @default.
• W2149590941 creator A5004768406 @default.
• W2149590941 creator A5005486528 @default.
• W2149590941 creator A5008865710 @default.
• W2149590941 creator A5014614899 @default.
• W2149590941 creator A5026363362 @default.
• W2149590941 creator A5026782825 @default.
• W2149590941 creator A5027177687 @default.
• W2149590941 creator A5034868328 @default.
• W2149590941 creator A5038978966 @default.
• W2149590941 creator A5046868443 @default.
• W2149590941 creator A5056532797 @default.
• W2149590941 creator A5058865450 @default.
• W2149590941 creator A5063566841 @default.
• W2149590941 creator A5063891743 @default.
• W2149590941 creator A5067029963 @default.
• W2149590941 creator A5069433387 @default.
• W2149590941 creator A5071598415 @default.
• W2149590941 creator A5072509115 @default.
• W2149590941 creator A5074907384 @default.
• W2149590941 creator A5074910135 @default.
• W2149590941 creator A5075665068 @default.
• W2149590941 creator A5077798378 @default.
• W2149590941 creator A5085670473 @default.
• W2149590941 creator A5086549966 @default.
• W2149590941 date "2006-06-01" @default.
• W2149590941 modified "2023-10-01" @default.
• W2149590941 title "Identification of an indole series of prostaglandin D2 receptor antagonists" @default.
• W2149590941 cites W1572774832 @default.
• W2149590941 cites W1680932833 @default.
• W2149590941 cites W1994424025 @default.
• W2149590941 cites W1999656621 @default.
• W2149590941 cites W2009345662 @default.
• W2149590941 cites W2027223183 @default.
• W2149590941 cites W2063136699 @default.
• W2149590941 cites W2063924884 @default.
• W2149590941 cites W2130414223 @default.
• W2149590941 cites W2949738588 @default.
• W2149590941 cites W2950076348 @default.
• W2149590941 cites W2952939347 @default.
• W2149590941 cites W2953194095 @default.
• W2149590941 cites W4250796891 @default.
• W2149590941 doi "https://doi.org/10.1016/j.bmcl.2006.02.062" @default.
• W2149590941 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16529930" @default.
• W2149590941 hasPublicationYear "2006" @default.
• W2149590941 type Work @default.
• W2149590941 sameAs 2149590941 @default.
• W2149590941 citedByCount "20" @default.
• W2149590941 countsByYear W21495909412013 @default.
• W2149590941 countsByYear W21495909412014 @default.
• W2149590941 countsByYear W21495909412015 @default.
• W2149590941 countsByYear W21495909412017 @default.
• W2149590941 countsByYear W21495909412018 @default.
• W2149590941 countsByYear W21495909412019 @default.
• W2149590941 crossrefType "journal-article" @default.
• W2149590941 hasAuthorship W2149590941A5004768406 @default.
• W2149590941 hasAuthorship W2149590941A5005486528 @default.
• W2149590941 hasAuthorship W2149590941A5008865710 @default.
• W2149590941 hasAuthorship W2149590941A5014614899 @default.
• W2149590941 hasAuthorship W2149590941A5026363362 @default.
• W2149590941 hasAuthorship W2149590941A5026782825 @default.
• W2149590941 hasAuthorship W2149590941A5027177687 @default.
• W2149590941 hasAuthorship W2149590941A5034868328 @default.
• W2149590941 hasAuthorship W2149590941A5038978966 @default.
• W2149590941 hasAuthorship W2149590941A5046868443 @default.
• W2149590941 hasAuthorship W2149590941A5056532797 @default.
• W2149590941 hasAuthorship W2149590941A5058865450 @default.
• W2149590941 hasAuthorship W2149590941A5063566841 @default.
• W2149590941 hasAuthorship W2149590941A5063891743 @default.
• W2149590941 hasAuthorship W2149590941A5067029963 @default.
• W2149590941 hasAuthorship W2149590941A5069433387 @default.
• W2149590941 hasAuthorship W2149590941A5071598415 @default.
• W2149590941 hasAuthorship W2149590941A5072509115 @default.
• W2149590941 hasAuthorship W2149590941A5074907384 @default.
• W2149590941 hasAuthorship W2149590941A5074910135 @default.
• W2149590941 hasAuthorship W2149590941A5075665068 @default.
• W2149590941 hasAuthorship W2149590941A5077798378 @default.
• W2149590941 hasAuthorship W2149590941A5085670473 @default.
• W2149590941 hasAuthorship W2149590941A5086549966 @default.
• W2149590941 hasConcept C114373084 @default.
• W2149590941 hasConcept C170493617 @default.
• W2149590941 hasConcept C185592680 @default.
• W2149590941 hasConcept C192527728 @default.
• W2149590941 hasConcept C202751555 @default.
• W2149590941 hasConcept C2776885963 @default.
• W2149590941 hasConcept C2777361909 @default.
• W2149590941 hasConcept C2777752497 @default.
• W2149590941 hasConcept C2780664492 @default.
• W2149590941 hasConcept C55493867 @default.
• W2149590941 hasConcept C71240020 @default.
• W2149590941 hasConcept C86803240 @default.
• W2149590941 hasConcept C98274493 @default.
• W2149590941 hasConceptScore W2149590941C114373084 @default.
• W2149590941 hasConceptScore W2149590941C170493617 @default.
• W2149590941 hasConceptScore W2149590941C185592680 @default.
• W2149590941 hasConceptScore W2149590941C192527728 @default.
• W2149590941 hasConceptScore W2149590941C202751555 @default.

• next