FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149605891> ?p ?o ?g. }

• W2149605891 endingPage "1250" @default.
• W2149605891 startingPage "1247" @default.
• W2149605891 abstract "It is widely accepted that B cells play an essential role in the pathogenesis of rheumatoid arthritis (RA). B cell involvement is well documented in the presence of detectable autoantibodies in the majority of patients, in particular, rheumatoid factor (RF) and antibodies against citrullinated proteins (ACPA), which can be detected many years before development of clinical disease, indicating that autoreactive B cell clones are involved in disease induction1. B cell depletion therapy with rituximab (anti-CD20) is effective in treating RA, proving an essential role for B cells in disease persistence2. Although B cell depletion therapy can induce longterm responses in a small number of patients, almost all patients eventually relapse. There is therefore much interest in finding out whether analysis of B cell-related factors can guide the development of treatment strategies and/or prediction of disease flare. The cytokine B cell activating factor (BAFF; also known as BLyS) plays an essential role in B cell survival and homeostasis. BAFF binds to 3 different receptors: BAFF-R, TACI, and BCMA. Expression of the different BAFF-binding receptors varies in distinct subsets of B cells, and their expression is coordinated and intimately related to maturation and activation status3. In the study by Moura, et al in this issue of The Journal 4, gene expression of molecules related to B cell survival and differentiation were studied in peripheral blood mononuclear cells (PBMC) in a small group of patients with very early RA (VERA; i.e., < 6 weeks of symptoms) and compared with other patients with RA at different stages [early RA (ERA) > 6 weeks and < 1 year duration; and established RA > 1 year duration], with patients with other forms of early arthritis (EA), and with healthy controls (HC). Patients with established RA were all taking methotrexate, … Address correspondence to Dr. M.J. Leandro, Centre for Rheumatology Research, Division of Medicine, University College London, Rayne Building, 5 University Street, London WC1E 6JF, UK; E-mail: maria.leandro{at}ucl.ac.uk" @default.
• W2149605891 created "2016-06-24" @default.
• W2149605891 creator A5072708850 @default.
• W2149605891 creator A5082185560 @default.
• W2149605891 date "2013-08-01" @default.
• W2149605891 modified "2023-09-28" @default.
• W2149605891 title "Expression of B Cell Activating Factor (BAFF) and BAFF-binding Receptors in Rheumatoid Arthritis" @default.
• W2149605891 cites W1651563658 @default.
• W2149605891 cites W1977206110 @default.
• W2149605891 cites W1980024538 @default.
• W2149605891 cites W1982703352 @default.
• W2149605891 cites W1998618256 @default.
• W2149605891 cites W2005634587 @default.
• W2149605891 cites W2019709522 @default.
• W2149605891 cites W2024988150 @default.
• W2149605891 cites W2040126057 @default.
• W2149605891 cites W2086729478 @default.
• W2149605891 cites W2088104857 @default.
• W2149605891 cites W2101755826 @default.
• W2149605891 cites W2102990692 @default.
• W2149605891 cites W2104413012 @default.
• W2149605891 cites W2118173089 @default.
• W2149605891 cites W2118994799 @default.
• W2149605891 cites W2122507029 @default.
• W2149605891 cites W2132246790 @default.
• W2149605891 cites W2139624120 @default.
• W2149605891 cites W2139998405 @default.
• W2149605891 cites W2141301927 @default.
• W2149605891 cites W2312932202 @default.
• W2149605891 doi "https://doi.org/10.3899/jrheum.130677" @default.
• W2149605891 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23908529" @default.
• W2149605891 hasPublicationYear "2013" @default.
• W2149605891 type Work @default.
• W2149605891 sameAs 2149605891 @default.
• W2149605891 citedByCount "9" @default.
• W2149605891 countsByYear W21496058912014 @default.
• W2149605891 countsByYear W21496058912015 @default.
• W2149605891 countsByYear W21496058912017 @default.
• W2149605891 countsByYear W21496058912020 @default.
• W2149605891 crossrefType "journal-article" @default.
• W2149605891 hasAuthorship W2149605891A5072708850 @default.
• W2149605891 hasAuthorship W2149605891A5082185560 @default.
• W2149605891 hasBestOaLocation W21496058911 @default.
• W2149605891 hasConcept C126322002 @default.
• W2149605891 hasConcept C137061746 @default.
• W2149605891 hasConcept C159654299 @default.
• W2149605891 hasConcept C163764329 @default.
• W2149605891 hasConcept C170286685 @default.
• W2149605891 hasConcept C170493617 @default.
• W2149605891 hasConcept C18031839 @default.
• W2149605891 hasConcept C202751555 @default.
• W2149605891 hasConcept C203014093 @default.
• W2149605891 hasConcept C2776232647 @default.
• W2149605891 hasConcept C2777575956 @default.
• W2149605891 hasConcept C2778453870 @default.
• W2149605891 hasConcept C2778690821 @default.
• W2149605891 hasConcept C2778957590 @default.
• W2149605891 hasConcept C2780653079 @default.
• W2149605891 hasConcept C2780942790 @default.
• W2149605891 hasConcept C55493867 @default.
• W2149605891 hasConcept C71924100 @default.
• W2149605891 hasConcept C86803240 @default.
• W2149605891 hasConceptScore W2149605891C126322002 @default.
• W2149605891 hasConceptScore W2149605891C137061746 @default.
• W2149605891 hasConceptScore W2149605891C159654299 @default.
• W2149605891 hasConceptScore W2149605891C163764329 @default.
• W2149605891 hasConceptScore W2149605891C170286685 @default.
• W2149605891 hasConceptScore W2149605891C170493617 @default.
• W2149605891 hasConceptScore W2149605891C18031839 @default.
• W2149605891 hasConceptScore W2149605891C202751555 @default.
• W2149605891 hasConceptScore W2149605891C203014093 @default.
• W2149605891 hasConceptScore W2149605891C2776232647 @default.
• W2149605891 hasConceptScore W2149605891C2777575956 @default.
• W2149605891 hasConceptScore W2149605891C2778453870 @default.
• W2149605891 hasConceptScore W2149605891C2778690821 @default.
• W2149605891 hasConceptScore W2149605891C2778957590 @default.
• W2149605891 hasConceptScore W2149605891C2780653079 @default.
• W2149605891 hasConceptScore W2149605891C2780942790 @default.
• W2149605891 hasConceptScore W2149605891C55493867 @default.
• W2149605891 hasConceptScore W2149605891C71924100 @default.
• W2149605891 hasConceptScore W2149605891C86803240 @default.
• W2149605891 hasIssue "8" @default.
• W2149605891 hasLocation W21496058911 @default.
• W2149605891 hasLocation W21496058912 @default.
• W2149605891 hasOpenAccess W2149605891 @default.
• W2149605891 hasPrimaryLocation W21496058911 @default.
• W2149605891 hasRelatedWork W1501243327 @default.
• W2149605891 hasRelatedWork W2010282370 @default.
• W2149605891 hasRelatedWork W2027119116 @default.
• W2149605891 hasRelatedWork W2030299551 @default.
• W2149605891 hasRelatedWork W2145073108 @default.
• W2149605891 hasRelatedWork W2322842969 @default.
• W2149605891 hasRelatedWork W2395968731 @default.
• W2149605891 hasRelatedWork W2521063508 @default.
• W2149605891 hasRelatedWork W3212764188 @default.
• W2149605891 hasRelatedWork W4288050659 @default.
• W2149605891 hasVolume "40" @default.
• W2149605891 isParatext "false" @default.

• next