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• W2149658905 abstract "<h3>Aims</h3> To externally validate the Endoscopic Third Ventriculostomy Success Score (ETVSS) recently found by Kulkarni <i>et al</i>1 to predict successful ETV for hydrocephalus, that is, child not requiring shunt or repeat ETV, on the basis of a child9s individual characteristics. The ETVSS is based upon patient age, aetiology and presence of a previous shunt. To date there has been no external validation of this model. We consider both short term and long term outcome, using a detailed large single centre series of paediatric patients with a long period of follow-up. <h3>Methods</h3> We retrospectively identified consecutive children undergoing ETV at a single regional neurosurgery centre. We compared actual success at both 6 and 36 months with mean predicted probabilities for low, moderate and high chance of success strata based on the ETVSS. Long-term success was calculated using Kaplan Meier methods and comparisons made by unpaired t tests. <h3>Results</h3> In total 166 primary ETV were performed at a median age of 39 (range 0.03–230) months. There was a greater number of patients in younger age groups in this series; 49 patients were under 6 months of age (29.5%) compared to 129 (20.9%) in the model dataset (difference 8.6%, CI 1.0 to 16.3; p=0.07). Overall, ETV success was 72.9% at 6 and 64.5% at 36 months. Although derived to predict outcome at 6 months, the model predicted outcome better on long-term follow-up than at 6 months. At long-term follow-up, the mean predicted probability was significantly higher in those with a successful ETV (n=99) than in those who failed (n=67) (p=0.001). The ETVSS accurately predicted long term success rates; the low, medium and high groups had mean predicted probabilities of 82%, 63% and 36% and overall success at 36 months of 76%, 66%, 42% respectively. The overall complication rate was 6%. <h3>Conclusion</h3> The ETVSS closely predicted the overall long term success rates in high, moderate and low risk groups. Our study suggests the ETVSS will be useful in the clinical decision-making in predicting long term outcome of ETV but further refinement of the model, validation and comparison with shunt treatment is required." @default.
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• W2149658905 date "2011-04-01" @default.
• W2149658905 modified "2023-10-09" @default.
• W2149658905 title "Hydrocephalus outcome: validation of endoscopic third ventriculostomy success score" @default.
• W2149658905 cites W2000331194 @default.
• W2149658905 doi "https://doi.org/10.1136/adc.2011.212563.87" @default.
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