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- W2149666022 abstract "To examine the relationship between progranulin gene mutation and apraxic agraphia.Case report.Tertiary care medical center.A 49-year-old right-handed woman who presented with apraxic agraphia that progressed into the corticobasal syndrome.This woman had no family history of neurodegenerative disease. Magnetic resonance imaging and fluorodeoxyglucose positron emission tomographic scans of her head revealed significant asymmetric frontoparietal abnormalities, in keeping with the clinical diagnosis of corticobasal syndrome. Progranulin gene sequencing identified a 4-base pair deletion.Patients presenting with early apraxic agraphia, a progressive disease course, and asymmetric frontoparietal abnormalities on brain scans should be considered for progranulin gene testing despite negative family history." @default.
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- W2149666022 date "2011-03-01" @default.
- W2149666022 modified "2023-09-23" @default.
- W2149666022 title "Sporadic Corticobasal Syndrome With Progranulin Mutation Presenting as Progressive Apraxic Agraphia" @default.
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- W2149666022 doi "https://doi.org/10.1001/archneurol.2011.26" @default.
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