FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149672304> ?p ?o ?g. }

• W2149672304 endingPage "804" @default.
• W2149672304 startingPage "799" @default.
• W2149672304 abstract "The role of opsonophagocytosis (OP) in protection against meningococcal disease is controversial because patients with deficiencies in terminal complement proteins whose sera support OP but not bactericidal activity (BA) are at greatly increased risk of disease. We assayed complement-mediated BA and OP bactericidal activity in sera from 32 adults immunized with an outer membrane vesicle vaccine given alone or combined with an investigational recombinant protein, genome-derived neisserial antigen (GNA2132). The sera were heat inactivated to remove internal complement activity, and BA was measured with exogenous nonimmune human serum as a complement source. OP was measured with human polymorphonuclear cells (PMNs) and C6-depleted complement, which without PMNs did not support BA. Before immunization, 9 to 19% of sera from subjects in both vaccine groups combined had BA titers of >or=1:4, which increased to 41 to 72% after immunization (P < 0.01 against each of three test strains). The percentages of sera with OP titers of >or=1:5 were 3 to 16%, which increased to 55 to 72% (P < 0.001 for each strain). Most postimmunization BA-positive sera were OP positive, but 10 to 37% of BA-negative sera also were OP positive. Comparing the two vaccine groups, there were no significant differences in the percentages of sera with BA or OP activity except for a higher percentage of OP against one strain in postimmunization sera from subjects in the combination vaccine group (P <or= 0.02). The data support independent roles for serum BA and OP bactericidal activity in protection against group B disease." @default.
• W2149672304 created "2016-06-24" @default.
• W2149672304 creator A5006315819 @default.
• W2149672304 creator A5017931794 @default.
• W2149672304 date "2008-05-01" @default.
• W2149672304 modified "2023-10-12" @default.
• W2149672304 title "Vaccine-Induced Opsonophagocytic Immunity to <i>Neisseria meningitidis</i> Group B" @default.
• W2149672304 cites W1966042875 @default.
• W2149672304 cites W1970280471 @default.
• W2149672304 cites W1978769545 @default.
• W2149672304 cites W1982086571 @default.
• W2149672304 cites W1990117641 @default.
• W2149672304 cites W1992548028 @default.
• W2149672304 cites W1998558781 @default.
• W2149672304 cites W2023869621 @default.
• W2149672304 cites W2033366028 @default.
• W2149672304 cites W2042304536 @default.
• W2149672304 cites W2047310221 @default.
• W2149672304 cites W2048133146 @default.
• W2149672304 cites W2086588297 @default.
• W2149672304 cites W2098499618 @default.
• W2149672304 cites W2102537411 @default.
• W2149672304 cites W2111315524 @default.
• W2149672304 cites W2115350923 @default.
• W2149672304 cites W2121388689 @default.
• W2149672304 cites W2124672930 @default.
• W2149672304 cites W2132306802 @default.
• W2149672304 cites W2134322626 @default.
• W2149672304 cites W2137675470 @default.
• W2149672304 cites W2171508764 @default.
• W2149672304 cites W2287518913 @default.
• W2149672304 cites W2335528859 @default.
• W2149672304 doi "https://doi.org/10.1128/cvi.00036-08" @default.
• W2149672304 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2394837" @default.
• W2149672304 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18353918" @default.
• W2149672304 hasPublicationYear "2008" @default.
• W2149672304 type Work @default.
• W2149672304 sameAs 2149672304 @default.
• W2149672304 citedByCount "47" @default.
• W2149672304 countsByYear W21496723042012 @default.
• W2149672304 countsByYear W21496723042013 @default.
• W2149672304 countsByYear W21496723042014 @default.
• W2149672304 countsByYear W21496723042015 @default.
• W2149672304 countsByYear W21496723042016 @default.
• W2149672304 countsByYear W21496723042017 @default.
• W2149672304 countsByYear W21496723042018 @default.
• W2149672304 countsByYear W21496723042019 @default.
• W2149672304 countsByYear W21496723042020 @default.
• W2149672304 countsByYear W21496723042021 @default.
• W2149672304 countsByYear W21496723042022 @default.
• W2149672304 countsByYear W21496723042023 @default.
• W2149672304 crossrefType "journal-article" @default.
• W2149672304 hasAuthorship W2149672304A5006315819 @default.
• W2149672304 hasAuthorship W2149672304A5017931794 @default.
• W2149672304 hasBestOaLocation W21496723041 @default.
• W2149672304 hasConcept C147483822 @default.
• W2149672304 hasConcept C159047783 @default.
• W2149672304 hasConcept C159654299 @default.
• W2149672304 hasConcept C203014093 @default.
• W2149672304 hasConcept C2776645655 @default.
• W2149672304 hasConcept C2778458888 @default.
• W2149672304 hasConcept C2779341262 @default.
• W2149672304 hasConcept C2780454893 @default.
• W2149672304 hasConcept C2780801004 @default.
• W2149672304 hasConcept C32611913 @default.
• W2149672304 hasConcept C523546767 @default.
• W2149672304 hasConcept C54355233 @default.
• W2149672304 hasConcept C86803240 @default.
• W2149672304 hasConcept C8891405 @default.
• W2149672304 hasConcept C89423630 @default.
• W2149672304 hasConceptScore W2149672304C147483822 @default.
• W2149672304 hasConceptScore W2149672304C159047783 @default.
• W2149672304 hasConceptScore W2149672304C159654299 @default.
• W2149672304 hasConceptScore W2149672304C203014093 @default.
• W2149672304 hasConceptScore W2149672304C2776645655 @default.
• W2149672304 hasConceptScore W2149672304C2778458888 @default.
• W2149672304 hasConceptScore W2149672304C2779341262 @default.
• W2149672304 hasConceptScore W2149672304C2780454893 @default.
• W2149672304 hasConceptScore W2149672304C2780801004 @default.
• W2149672304 hasConceptScore W2149672304C32611913 @default.
• W2149672304 hasConceptScore W2149672304C523546767 @default.
• W2149672304 hasConceptScore W2149672304C54355233 @default.
• W2149672304 hasConceptScore W2149672304C86803240 @default.
• W2149672304 hasConceptScore W2149672304C8891405 @default.
• W2149672304 hasConceptScore W2149672304C89423630 @default.
• W2149672304 hasIssue "5" @default.
• W2149672304 hasLocation W21496723041 @default.
• W2149672304 hasLocation W21496723042 @default.
• W2149672304 hasLocation W21496723043 @default.
• W2149672304 hasLocation W21496723044 @default.
• W2149672304 hasOpenAccess W2149672304 @default.
• W2149672304 hasPrimaryLocation W21496723041 @default.
• W2149672304 hasRelatedWork W2021588001 @default.
• W2149672304 hasRelatedWork W2048853144 @default.
• W2149672304 hasRelatedWork W2049463023 @default.
• W2149672304 hasRelatedWork W2070553347 @default.
• W2149672304 hasRelatedWork W2163631167 @default.
• W2149672304 hasRelatedWork W2258349998 @default.

• next