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- W2149686684 abstract "Because melatonin mimics the effects of microtubular disruptive agents (e.g., colchicine) in various cellular systems, we have examined its effect on water transport in the toad urinary bladder. Microtubules are essential to vasopressin-stimulated water transport in this tissue and are labile to colchicine (Kachadorian et al., '79). In unstimulated urinary bladders, melatonin is without effect; however, in the presence of 20 μ/ml of vasopressin, 4 × 10−6M melatonin significantly reduced the stimulation of water transport in this preparation. The inhibition of water transport by melatonin is comparable to that effected by colchicine. The possibility that melatonin may modulate microtubular functions is discussed." @default.
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- W2149686684 date "1980-03-01" @default.
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- W2149686684 title "Melatonin inhibition of vasopressin-stimulated water transport in the toad urinary bladder" @default.
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- W2149686684 doi "https://doi.org/10.1002/jez.1402110318" @default.
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