Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149691861> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2149691861 endingPage "101" @default.
- W2149691861 startingPage "97" @default.
- W2149691861 abstract "Concern exists regarding the negative inotropic and chronotropic effects of verapamil given to patients receiving chronic propranolol therapy. In order to evaluate the safety of combined therapy, the hemodynamic effects of verapamil were investigated in a group of 19 patients on chronic propranolol therapy undergoing cardiac catheterization. Hemodynamic measurements and left ventriculography were performed prior to and 30 minutes after initiation of intravenous administration of verapamil. Verapamil doses varied from 0.025 mg/kg to 0.1 mg/kg intravenous bolus injection followed by an infusion of 0.005 mg/kg/min. Following verapamil administration, systolic, diastolic, and arterial mean pressures and systemic vascular resistance decreased significantly. There was no significant change in left ventricular end-diastolic pressure, mean pulmonary capillary wedge pressure, cardiac index, arteriovenous oxygen difference, heart rate, mean velocity of circumferential fiber shortening (VCF), end-diastolic volume index, end-systolic volume index, stroke volume index, and ejection fraction (EF). Stroke work index decreased significantly. Lack of improvement in cardiac index, VCF, and EF and decrease in stroke work index in spite of constant filling pressure and decreased afterload suggest the additive negative inotropic action of verapamil. The depressant action of propranolol itself was not determined by this study. In spite of the negative inotropic effect of verapamil, it can be administered acutely to patients who have been on propranolol therapy with relative safety if the propranolol has not already produced severe left ventricular dysfunction, relative hypotension, bradyarrhythmia, or conduction abnormalities." @default.
- W2149691861 created "2016-06-24" @default.
- W2149691861 creator A5064793472 @default.
- W2149691861 creator A5066185737 @default.
- W2149691861 creator A5076001000 @default.
- W2149691861 date "1984-01-01" @default.
- W2149691861 modified "2023-10-07" @default.
- W2149691861 title "The hemodynamic effects of intravenous verapamil in patients on chronic propranolol therapy" @default.
- W2149691861 cites W1968289991 @default.
- W2149691861 cites W1970301854 @default.
- W2149691861 cites W1984837851 @default.
- W2149691861 cites W1985500599 @default.
- W2149691861 cites W1992435167 @default.
- W2149691861 cites W1992648216 @default.
- W2149691861 cites W2000583605 @default.
- W2149691861 cites W2014070550 @default.
- W2149691861 cites W2026275409 @default.
- W2149691861 cites W2054444586 @default.
- W2149691861 cites W2058297258 @default.
- W2149691861 cites W2075936164 @default.
- W2149691861 cites W2093360413 @default.
- W2149691861 cites W2093495045 @default.
- W2149691861 cites W2143034073 @default.
- W2149691861 cites W2169361798 @default.
- W2149691861 cites W4252557325 @default.
- W2149691861 doi "https://doi.org/10.1016/0002-8703(84)90140-6" @default.
- W2149691861 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6691247" @default.
- W2149691861 hasPublicationYear "1984" @default.
- W2149691861 type Work @default.
- W2149691861 sameAs 2149691861 @default.
- W2149691861 citedByCount "18" @default.
- W2149691861 crossrefType "journal-article" @default.
- W2149691861 hasAuthorship W2149691861A5064793472 @default.
- W2149691861 hasAuthorship W2149691861A5066185737 @default.
- W2149691861 hasAuthorship W2149691861A5076001000 @default.
- W2149691861 hasConcept C123576724 @default.
- W2149691861 hasConcept C126322002 @default.
- W2149691861 hasConcept C139940330 @default.
- W2149691861 hasConcept C146556889 @default.
- W2149691861 hasConcept C155710745 @default.
- W2149691861 hasConcept C158328960 @default.
- W2149691861 hasConcept C164705383 @default.
- W2149691861 hasConcept C178853913 @default.
- W2149691861 hasConcept C2777022698 @default.
- W2149691861 hasConcept C2777953023 @default.
- W2149691861 hasConcept C2778151854 @default.
- W2149691861 hasConcept C31861589 @default.
- W2149691861 hasConcept C42219234 @default.
- W2149691861 hasConcept C519063684 @default.
- W2149691861 hasConcept C58245268 @default.
- W2149691861 hasConcept C71924100 @default.
- W2149691861 hasConcept C80461066 @default.
- W2149691861 hasConcept C84393581 @default.
- W2149691861 hasConceptScore W2149691861C123576724 @default.
- W2149691861 hasConceptScore W2149691861C126322002 @default.
- W2149691861 hasConceptScore W2149691861C139940330 @default.
- W2149691861 hasConceptScore W2149691861C146556889 @default.
- W2149691861 hasConceptScore W2149691861C155710745 @default.
- W2149691861 hasConceptScore W2149691861C158328960 @default.
- W2149691861 hasConceptScore W2149691861C164705383 @default.
- W2149691861 hasConceptScore W2149691861C178853913 @default.
- W2149691861 hasConceptScore W2149691861C2777022698 @default.
- W2149691861 hasConceptScore W2149691861C2777953023 @default.
- W2149691861 hasConceptScore W2149691861C2778151854 @default.
- W2149691861 hasConceptScore W2149691861C31861589 @default.
- W2149691861 hasConceptScore W2149691861C42219234 @default.
- W2149691861 hasConceptScore W2149691861C519063684 @default.
- W2149691861 hasConceptScore W2149691861C58245268 @default.
- W2149691861 hasConceptScore W2149691861C71924100 @default.
- W2149691861 hasConceptScore W2149691861C80461066 @default.
- W2149691861 hasConceptScore W2149691861C84393581 @default.
- W2149691861 hasIssue "1" @default.
- W2149691861 hasLocation W21496918611 @default.
- W2149691861 hasLocation W21496918612 @default.
- W2149691861 hasOpenAccess W2149691861 @default.
- W2149691861 hasPrimaryLocation W21496918611 @default.
- W2149691861 hasRelatedWork W1977334634 @default.
- W2149691861 hasRelatedWork W2014491913 @default.
- W2149691861 hasRelatedWork W2035452547 @default.
- W2149691861 hasRelatedWork W2040462779 @default.
- W2149691861 hasRelatedWork W2142941962 @default.
- W2149691861 hasRelatedWork W2149691861 @default.
- W2149691861 hasRelatedWork W2170363682 @default.
- W2149691861 hasRelatedWork W2314165071 @default.
- W2149691861 hasRelatedWork W2414900474 @default.
- W2149691861 hasRelatedWork W2475327391 @default.
- W2149691861 hasVolume "107" @default.
- W2149691861 isParatext "false" @default.
- W2149691861 isRetracted "false" @default.
- W2149691861 magId "2149691861" @default.
- W2149691861 workType "article" @default.