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• W2149746574 endingPage "3626" @default.
• W2149746574 startingPage "3621" @default.
• W2149746574 abstract "ABSTRACT Immunological and epidemiological evidence suggests that the development of natural immunity to meningococcal disease results from colonization of the nasopharynx by commensal Neisseria spp., particularly with N. lactamica . We report here that immunization with N. lactamica killed whole cells, outer membrane vesicles, or outer membrane protein (OMP) pools and protected mice against lethal challenge by a number of diverse serogroup B and C meningococcal isolates in a model of bacteremic infection. Sera raised to N. lactamica killed whole cells, OMPs, or protein pools were found to cross-react with meningococcal isolates of a diverse range of genotypes and phenotypes. The results confirm the potential of N. lactamica to form the basis of a vaccine against meningococcal disease." @default.
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• W2149746574 date "2002-07-01" @default.
• W2149746574 modified "2023-10-16" @default.
• W2149746574 title "<i>Neisseria lactamica</i> Protects against Experimental Meningococcal Infection" @default.
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• W2149746574 doi "https://doi.org/10.1128/iai.70.7.3621-3626.2002" @default.
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