FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149758203> ?p ?o ?g. }

• W2149758203 endingPage "e57159" @default.
• W2149758203 startingPage "e57159" @default.
• W2149758203 abstract "Compartments are units of cell lineage that subdivide territories with different developmental potential. In Drosophila, the wing and haltere discs are subdivided into anterior and posterior (A/P) compartments, which require the activity of Hedgehog, and into dorsal and ventral (D/V) compartments, needing Notch signaling. There is enrichment in actomyosin proteins at the compartment boundaries, suggesting a role for these proteins in their maintenance. Compartments also develop in the mouse hindbrain rhombomeres, which are characterized by the expression of different Hox genes, a group of genes specifying different structures along their main axis of bilaterians. We show here that the Drosophila Hox gene Ultrabithorax can maintain the A/P and D/V compartment boundaries when Hedgehog or Notch signaling is compromised, and that the interaction of cells with and without Ultrabithorax expression induces high levels of non-muscle myosin II. In the absence of Ultrabithorax there is occasional mixing of cells from different segments. We also show a similar role in cell segregation for the Abdominal-B Hox gene. Our results suggest that the juxtaposition of cells with different Hox gene expression leads to their sorting out, probably through the accumulation of non-muscle myosin II at the boundary of the different cell territories. The increase in myosin expression seems to be a general mechanism used by Hox genes or signaling pathways to maintain the segregation of different groups of cells." @default.
• W2149758203 created "2016-06-24" @default.
• W2149758203 creator A5028502151 @default.
• W2149758203 creator A5054627494 @default.
• W2149758203 creator A5079583854 @default.
• W2149758203 date "2013-02-25" @default.
• W2149758203 modified "2023-10-05" @default.
• W2149758203 title "Differential Activity of Drosophila Hox Genes Induces Myosin Expression and Can Maintain Compartment Boundaries" @default.
• W2149758203 cites W1550395484 @default.
• W2149758203 cites W1561060766 @default.
• W2149758203 cites W1594995183 @default.
• W2149758203 cites W1639210574 @default.
• W2149758203 cites W1652763473 @default.
• W2149758203 cites W1669006776 @default.
• W2149758203 cites W1965849408 @default.
• W2149758203 cites W1969967829 @default.
• W2149758203 cites W1973449779 @default.
• W2149758203 cites W1975419284 @default.
• W2149758203 cites W1988729681 @default.
• W2149758203 cites W1990478485 @default.
• W2149758203 cites W1992383169 @default.
• W2149758203 cites W1994085844 @default.
• W2149758203 cites W1995112067 @default.
• W2149758203 cites W1999155535 @default.
• W2149758203 cites W2000520401 @default.
• W2149758203 cites W2010480976 @default.
• W2149758203 cites W2016636886 @default.
• W2149758203 cites W2019133627 @default.
• W2149758203 cites W2020481907 @default.
• W2149758203 cites W2029092025 @default.
• W2149758203 cites W2032419889 @default.
• W2149758203 cites W2041519679 @default.
• W2149758203 cites W2046490342 @default.
• W2149758203 cites W2049717930 @default.
• W2149758203 cites W2064469337 @default.
• W2149758203 cites W2066853527 @default.
• W2149758203 cites W2081092282 @default.
• W2149758203 cites W2081748379 @default.
• W2149758203 cites W2086322797 @default.
• W2149758203 cites W2091405398 @default.
• W2149758203 cites W2091739086 @default.
• W2149758203 cites W2093787144 @default.
• W2149758203 cites W2094356495 @default.
• W2149758203 cites W2103046819 @default.
• W2149758203 cites W2123544339 @default.
• W2149758203 cites W2127587858 @default.
• W2149758203 cites W2131982123 @default.
• W2149758203 cites W2138587742 @default.
• W2149758203 cites W2402535089 @default.
• W2149758203 doi "https://doi.org/10.1371/journal.pone.0057159" @default.
• W2149758203 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3581558" @default.
• W2149758203 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23451173" @default.
• W2149758203 hasPublicationYear "2013" @default.
• W2149758203 type Work @default.
• W2149758203 sameAs 2149758203 @default.
• W2149758203 citedByCount "8" @default.
• W2149758203 countsByYear W21497582032014 @default.
• W2149758203 countsByYear W21497582032015 @default.
• W2149758203 countsByYear W21497582032016 @default.
• W2149758203 countsByYear W21497582032017 @default.
• W2149758203 countsByYear W21497582032020 @default.
• W2149758203 countsByYear W21497582032023 @default.
• W2149758203 crossrefType "journal-article" @default.
• W2149758203 hasAuthorship W2149758203A5028502151 @default.
• W2149758203 hasAuthorship W2149758203A5054627494 @default.
• W2149758203 hasAuthorship W2149758203A5079583854 @default.
• W2149758203 hasBestOaLocation W21497582031 @default.
• W2149758203 hasConcept C104317684 @default.
• W2149758203 hasConcept C111039654 @default.
• W2149758203 hasConcept C111368507 @default.
• W2149758203 hasConcept C121587040 @default.
• W2149758203 hasConcept C127313418 @default.
• W2149758203 hasConcept C145103041 @default.
• W2149758203 hasConcept C150194340 @default.
• W2149758203 hasConcept C197564579 @default.
• W2149758203 hasConcept C203635412 @default.
• W2149758203 hasConcept C2778539099 @default.
• W2149758203 hasConcept C2780172944 @default.
• W2149758203 hasConcept C2780915607 @default.
• W2149758203 hasConcept C54355233 @default.
• W2149758203 hasConcept C62478195 @default.
• W2149758203 hasConcept C6997183 @default.
• W2149758203 hasConcept C86803240 @default.
• W2149758203 hasConcept C95444343 @default.
• W2149758203 hasConceptScore W2149758203C104317684 @default.
• W2149758203 hasConceptScore W2149758203C111039654 @default.
• W2149758203 hasConceptScore W2149758203C111368507 @default.
• W2149758203 hasConceptScore W2149758203C121587040 @default.
• W2149758203 hasConceptScore W2149758203C127313418 @default.
• W2149758203 hasConceptScore W2149758203C145103041 @default.
• W2149758203 hasConceptScore W2149758203C150194340 @default.
• W2149758203 hasConceptScore W2149758203C197564579 @default.
• W2149758203 hasConceptScore W2149758203C203635412 @default.
• W2149758203 hasConceptScore W2149758203C2778539099 @default.
• W2149758203 hasConceptScore W2149758203C2780172944 @default.
• W2149758203 hasConceptScore W2149758203C2780915607 @default.
• W2149758203 hasConceptScore W2149758203C54355233 @default.
• W2149758203 hasConceptScore W2149758203C62478195 @default.

• next