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- W2149774932 abstract "We formulate and investigate the properties of a model framework to mimic the transmission dynamics of the aetiological agent of scrapie in a sheep flock. We derive expressions for summary parameters that characterize transmission scenarios, notably the basic reproduction number R(0) and the mean generation time T(g). The timescale of epidemic outbreaks is expressed in terms of R(0) and cumulants of the generation time distribution. We discuss the relative contributions to the overall rate of transmission of horizontal and vertical routes during invasion and in endemicity. Simplified models are used to obtain analytical insight into the characteristics of the endemic state." @default.
- W2149774932 created "2016-06-24" @default.
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- W2149774932 date "2000-12-01" @default.
- W2149774932 modified "2023-09-27" @default.
- W2149774932 title "The transmission dynamics of the aetiological agent of scrapie in a sheep flock" @default.
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- W2149774932 doi "https://doi.org/10.1016/s0025-5564(00)00048-1" @default.
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