FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149785950> ?p ?o ?g. }

• W2149785950 endingPage "208" @default.
• W2149785950 startingPage "203" @default.
• W2149785950 abstract "To assess compliance to current surgical staging and adjuvant treatment guidelines for patients with early-stage epithelial ovarian carcinoma and its impact on overall survival.Patients diagnosed between 1991 and 1997 with early-stage ovarian cancer were recruited from the Regional Cancer Registry of the central region in the Netherlands. Demographic data, tumour characteristics, surgical findings and therapeutic data were abstracted from medical records. Patients were classified into optimal and non-optimal surgical staging. Overall survival was estimated using Kaplan-Meier method. To adjust for age hazard ratios for overall survival were estimated with a Cox Proportional Hazards model.One hundred and twenty-five patients were included in the study, 41 of them (32.8%) were optimally staged. Guidelines for adjuvant radio- or chemotherapy were adequately followed in all 62 grade I patients and in 44 out of 59 grade II and III patients (74.6%). During 734.6 person-years of follow up 31 patients died. Five-year overall survival figures were 97.6% in the optimally staged group and 68.5% in the non-optimally staged group. Patients who were non-optimally staged, had a significant higher risk to die than those who were optimally staged (HR: 7.4; 95% CI: 1.7-32.2). In patients with a grade II and III tumours, complete surgical staging still had a significant influence on survival (HR: 3.8; 95% CI 1.7-8.3). In women with grade II or III tumours, adjuvant radio- or chemotherapy administered in accordance to the guidelines did not improve overall survival regardless whether they were optimally staged or not.Incomplete staging in early-stage ovarian cancer leads to gross mis-classification in grade II and III tumours and to a lesser extent in grade I tumours. This leads to undertreatment in both surgical and adjuvant therapy. Subsequently unnecessary deaths may occur. More effort must be put in identifying obstacles interfering with compliance of guidelines." @default.
• W2149785950 created "2016-06-24" @default.
• W2149785950 creator A5013836299 @default.
• W2149785950 creator A5025082485 @default.
• W2149785950 creator A5026672850 @default.
• W2149785950 creator A5043481012 @default.
• W2149785950 creator A5057103027 @default.
• W2149785950 creator A5067857902 @default.
• W2149785950 date "2007-04-01" @default.
• W2149785950 modified "2023-09-26" @default.
• W2149785950 title "Compliance to clinical guidelines for early-stage epithelial ovarian cancer in relation to patient outcome" @default.
• W2149785950 cites W1513348879 @default.
• W2149785950 cites W1513512556 @default.
• W2149785950 cites W1884062425 @default.
• W2149785950 cites W1965111455 @default.
• W2149785950 cites W2042367850 @default.
• W2149785950 cites W2058192214 @default.
• W2149785950 cites W2060142689 @default.
• W2149785950 cites W2070402583 @default.
• W2149785950 cites W2086519127 @default.
• W2149785950 cites W2100030862 @default.
• W2149785950 doi "https://doi.org/10.1016/j.ejogrb.2006.03.014" @default.
• W2149785950 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16707204" @default.
• W2149785950 hasPublicationYear "2007" @default.
• W2149785950 type Work @default.
• W2149785950 sameAs 2149785950 @default.
• W2149785950 citedByCount "19" @default.
• W2149785950 countsByYear W21497859502012 @default.
• W2149785950 countsByYear W21497859502014 @default.
• W2149785950 countsByYear W21497859502015 @default.
• W2149785950 countsByYear W21497859502016 @default.
• W2149785950 countsByYear W21497859502019 @default.
• W2149785950 countsByYear W21497859502020 @default.
• W2149785950 countsByYear W21497859502021 @default.
• W2149785950 countsByYear W21497859502022 @default.
• W2149785950 countsByYear W21497859502023 @default.
• W2149785950 crossrefType "journal-article" @default.
• W2149785950 hasAuthorship W2149785950A5013836299 @default.
• W2149785950 hasAuthorship W2149785950A5025082485 @default.
• W2149785950 hasAuthorship W2149785950A5026672850 @default.
• W2149785950 hasAuthorship W2149785950A5043481012 @default.
• W2149785950 hasAuthorship W2149785950A5057103027 @default.
• W2149785950 hasAuthorship W2149785950A5067857902 @default.
• W2149785950 hasBestOaLocation W21497859502 @default.
• W2149785950 hasConcept C10515644 @default.
• W2149785950 hasConcept C121608353 @default.
• W2149785950 hasConcept C126322002 @default.
• W2149785950 hasConcept C141071460 @default.
• W2149785950 hasConcept C143998085 @default.
• W2149785950 hasConcept C146357865 @default.
• W2149785950 hasConcept C151730666 @default.
• W2149785950 hasConcept C195910791 @default.
• W2149785950 hasConcept C207103383 @default.
• W2149785950 hasConcept C2776694085 @default.
• W2149785950 hasConcept C2778527826 @default.
• W2149785950 hasConcept C2780427987 @default.
• W2149785950 hasConcept C44249647 @default.
• W2149785950 hasConcept C50382708 @default.
• W2149785950 hasConcept C71924100 @default.
• W2149785950 hasConcept C86803240 @default.
• W2149785950 hasConceptScore W2149785950C10515644 @default.
• W2149785950 hasConceptScore W2149785950C121608353 @default.
• W2149785950 hasConceptScore W2149785950C126322002 @default.
• W2149785950 hasConceptScore W2149785950C141071460 @default.
• W2149785950 hasConceptScore W2149785950C143998085 @default.
• W2149785950 hasConceptScore W2149785950C146357865 @default.
• W2149785950 hasConceptScore W2149785950C151730666 @default.
• W2149785950 hasConceptScore W2149785950C195910791 @default.
• W2149785950 hasConceptScore W2149785950C207103383 @default.
• W2149785950 hasConceptScore W2149785950C2776694085 @default.
• W2149785950 hasConceptScore W2149785950C2778527826 @default.
• W2149785950 hasConceptScore W2149785950C2780427987 @default.
• W2149785950 hasConceptScore W2149785950C44249647 @default.
• W2149785950 hasConceptScore W2149785950C50382708 @default.
• W2149785950 hasConceptScore W2149785950C71924100 @default.
• W2149785950 hasConceptScore W2149785950C86803240 @default.
• W2149785950 hasIssue "2" @default.
• W2149785950 hasLocation W21497859501 @default.
• W2149785950 hasLocation W21497859502 @default.
• W2149785950 hasLocation W21497859503 @default.
• W2149785950 hasOpenAccess W2149785950 @default.
• W2149785950 hasPrimaryLocation W21497859501 @default.
• W2149785950 hasRelatedWork W167319750 @default.
• W2149785950 hasRelatedWork W1967715255 @default.
• W2149785950 hasRelatedWork W1987468340 @default.
• W2149785950 hasRelatedWork W2118215538 @default.
• W2149785950 hasRelatedWork W2783585287 @default.
• W2149785950 hasRelatedWork W2994686985 @default.
• W2149785950 hasRelatedWork W3047309708 @default.
• W2149785950 hasRelatedWork W4242937576 @default.
• W2149785950 hasRelatedWork W4281727781 @default.
• W2149785950 hasRelatedWork W4322099846 @default.
• W2149785950 hasVolume "131" @default.
• W2149785950 isParatext "false" @default.
• W2149785950 isRetracted "false" @default.
• W2149785950 magId "2149785950" @default.
• W2149785950 workType "article" @default.