Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149791119> ?p ?o ?g. }
- W2149791119 endingPage "12" @default.
- W2149791119 startingPage "2" @default.
- W2149791119 abstract "Chromogranin A is the quantitatively major soluble protein in catecholamine storage vesicles of the adrenal medulla and sympathetic nerve, and has been a useful index of exocytosis during sympathoadrenal neurosecretion. To probe human catecholamine storage and release, we isolated chromogranin A from chromaffin tissue in human pheochromocytoma, and compared it to chromogranin A isolated from chromaffin tissue in bovine adrenal medulla. The preparation included catecholamine storage vesicle isolation by sucrose gradient centrifugation, removal of dopamine-beta-hydroxylase by affinity chromatography on Concanavalin A-Sepharose, and preparative polyacrylamide gel electrophoresis. Human and bovine chromogranin A displayed considerable interspecies homology. Human chromogranin A is a 68,000 dalton monomeric protein with an unusual amino acid composition (31.53 weight % glutamic acid); an acidic, microheterogeneous isoelectric point (4.57-4.68); a characteristic tryptic digest peptide map; and marked dissimilarity to dopamine-beta-hydroxylase in all properties studied. A new probe of human sympathoadrenal function is available in chromogranin A." @default.
- W2149791119 created "2016-06-24" @default.
- W2149791119 creator A5037365117 @default.
- W2149791119 creator A5047949745 @default.
- W2149791119 creator A5060070231 @default.
- W2149791119 date "1984-01-01" @default.
- W2149791119 modified "2023-10-03" @default.
- W2149791119 title "Human chromogranin A. Purification and characterization from catecholamine storage vesicles of human pheochromocytoma." @default.
- W2149791119 cites W1093746230 @default.
- W2149791119 cites W1150077517 @default.
- W2149791119 cites W1436444740 @default.
- W2149791119 cites W1483332610 @default.
- W2149791119 cites W1512590156 @default.
- W2149791119 cites W1561799415 @default.
- W2149791119 cites W1625660792 @default.
- W2149791119 cites W1964865241 @default.
- W2149791119 cites W1965846839 @default.
- W2149791119 cites W1971943926 @default.
- W2149791119 cites W1977485135 @default.
- W2149791119 cites W1977756360 @default.
- W2149791119 cites W1985585787 @default.
- W2149791119 cites W1993224614 @default.
- W2149791119 cites W1993902942 @default.
- W2149791119 cites W2007534334 @default.
- W2149791119 cites W2009486391 @default.
- W2149791119 cites W2010692012 @default.
- W2149791119 cites W2011280528 @default.
- W2149791119 cites W2023085928 @default.
- W2149791119 cites W2033524205 @default.
- W2149791119 cites W2034427128 @default.
- W2149791119 cites W2035691399 @default.
- W2149791119 cites W2048071243 @default.
- W2149791119 cites W2052678266 @default.
- W2149791119 cites W2052700765 @default.
- W2149791119 cites W2081677706 @default.
- W2149791119 cites W2081828201 @default.
- W2149791119 cites W2092657822 @default.
- W2149791119 cites W2093169996 @default.
- W2149791119 cites W2100837269 @default.
- W2149791119 cites W2223862935 @default.
- W2149791119 cites W2226650408 @default.
- W2149791119 cites W2233707407 @default.
- W2149791119 cites W2400932424 @default.
- W2149791119 cites W2475449991 @default.
- W2149791119 cites W4293247451 @default.
- W2149791119 cites W940916854 @default.
- W2149791119 doi "https://doi.org/10.1161/01.hyp.6.1.2" @default.
- W2149791119 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6693145" @default.
- W2149791119 hasPublicationYear "1984" @default.
- W2149791119 type Work @default.
- W2149791119 sameAs 2149791119 @default.
- W2149791119 citedByCount "102" @default.
- W2149791119 countsByYear W21497911192013 @default.
- W2149791119 countsByYear W21497911192016 @default.
- W2149791119 countsByYear W21497911192018 @default.
- W2149791119 countsByYear W21497911192019 @default.
- W2149791119 countsByYear W21497911192020 @default.
- W2149791119 countsByYear W21497911192021 @default.
- W2149791119 countsByYear W21497911192023 @default.
- W2149791119 crossrefType "journal-article" @default.
- W2149791119 hasAuthorship W2149791119A5037365117 @default.
- W2149791119 hasAuthorship W2149791119A5047949745 @default.
- W2149791119 hasAuthorship W2149791119A5060070231 @default.
- W2149791119 hasBestOaLocation W21497911191 @default.
- W2149791119 hasConcept C126322002 @default.
- W2149791119 hasConcept C134018914 @default.
- W2149791119 hasConcept C185592680 @default.
- W2149791119 hasConcept C204232928 @default.
- W2149791119 hasConcept C2775894120 @default.
- W2149791119 hasConcept C2777597313 @default.
- W2149791119 hasConcept C2779512018 @default.
- W2149791119 hasConcept C2780910648 @default.
- W2149791119 hasConcept C55493867 @default.
- W2149791119 hasConcept C71924100 @default.
- W2149791119 hasConcept C77231918 @default.
- W2149791119 hasConcept C86803240 @default.
- W2149791119 hasConceptScore W2149791119C126322002 @default.
- W2149791119 hasConceptScore W2149791119C134018914 @default.
- W2149791119 hasConceptScore W2149791119C185592680 @default.
- W2149791119 hasConceptScore W2149791119C204232928 @default.
- W2149791119 hasConceptScore W2149791119C2775894120 @default.
- W2149791119 hasConceptScore W2149791119C2777597313 @default.
- W2149791119 hasConceptScore W2149791119C2779512018 @default.
- W2149791119 hasConceptScore W2149791119C2780910648 @default.
- W2149791119 hasConceptScore W2149791119C55493867 @default.
- W2149791119 hasConceptScore W2149791119C71924100 @default.
- W2149791119 hasConceptScore W2149791119C77231918 @default.
- W2149791119 hasConceptScore W2149791119C86803240 @default.
- W2149791119 hasIssue "1" @default.
- W2149791119 hasLocation W21497911191 @default.
- W2149791119 hasLocation W21497911192 @default.
- W2149791119 hasOpenAccess W2149791119 @default.
- W2149791119 hasPrimaryLocation W21497911191 @default.
- W2149791119 hasRelatedWork W1979016437 @default.
- W2149791119 hasRelatedWork W2002000499 @default.
- W2149791119 hasRelatedWork W2022001512 @default.
- W2149791119 hasRelatedWork W2024855671 @default.
- W2149791119 hasRelatedWork W2038512896 @default.