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• W2149792163 abstract "Significance The master cell-cycle processes governing DNA replication and mitosis in eukaryotic cells are regulated by cyclin/cyclin dependent kinase 1 and the anaphase-promoting complex, with checkpoint activity on these regulators. It is not these regulators but rather intermediaries that communicate to the processes. Here we show that the protein Geminin acts centrally in controlling DNA replication by ensuring that DNA is replicated during S phase and only once. This paper describes the Geminin “sub-master” regulatory circuit and the central role of Geminin in controlling events of the cell cycle." @default.
• W2149792163 created "2016-06-24" @default.
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• W2149792163 date "2013-07-08" @default.
• W2149792163 modified "2023-10-14" @default.
• W2149792163 title "Geminin deploys multiple mechanisms to regulate Cdt1 before cell division thus ensuring the proper execution of DNA replication" @default.
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• W2149792163 doi "https://doi.org/10.1073/pnas.1310677110" @default.
• W2149792163 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3725105" @default.
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