FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149802606> ?p ?o ?g. }

• W2149802606 endingPage "1042" @default.
• W2149802606 startingPage "1035" @default.
• W2149802606 abstract "Purpose: To investigate possible variations in topoisomerase (topo) I and II activities and levels after X-ray treatment in the radiation repair proficient AA8 Chinese hamster cell line for comparison with the radiation sensitive mutant EM9. Materials and methods: AA8 and EM9 cells were irradiated with 5Gy of X-rays and the activities of topoisomerases I and II in nuclear extracts were studied. Immunological detection of both topoisomerases was carried out in order to detect any changes in the expression of these enzymes as a consequence of irradiation. Results: Topoisomerase activities and levels in irradiated EM9 cells were the same as in control non-irradiated cells. In fact, both topo I and topo II activities clearly increased shortly after irradiation in the parental AA8 cells, with a more rapid increase for topo I than for topo II. In the AA8 cells, an increased level of topo I detectable immunologically was only observed at a later time (1h) after irradiation, while no similar change was detectable for topo II. Conclusions: While this hypothesis needs further testing, an attractive idea is that DNA topoisomerases might be involved in the cellular response to radiation damage, either through a direct participation in repair mechanisms or indirectly." @default.
• W2149802606 created "2016-06-24" @default.
• W2149802606 creator A5008654635 @default.
• W2149802606 creator A5029195570 @default.
• W2149802606 creator A5073113433 @default.
• W2149802606 creator A5078888968 @default.
• W2149802606 creator A5085973884 @default.
• W2149802606 creator A5089441565 @default.
• W2149802606 date "1999-01-01" @default.
• W2149802606 modified "2023-10-18" @default.
• W2149802606 title "Topoisomerase activities and levels in irradiated Chinese hamster AA8 cells and in its radiosensitive mutant EM9" @default.
• W2149802606 cites W1488959765 @default.
• W2149802606 cites W1491876634 @default.
• W2149802606 cites W1502059603 @default.
• W2149802606 cites W1557550609 @default.
• W2149802606 cites W1581614904 @default.
• W2149802606 cites W1968975825 @default.
• W2149802606 cites W1969656310 @default.
• W2149802606 cites W1981491056 @default.
• W2149802606 cites W1988613599 @default.
• W2149802606 cites W1995845243 @default.
• W2149802606 cites W2015000379 @default.
• W2149802606 cites W2016240319 @default.
• W2149802606 cites W2019779629 @default.
• W2149802606 cites W2024815175 @default.
• W2149802606 cites W2031460204 @default.
• W2149802606 cites W2034685457 @default.
• W2149802606 cites W2036511917 @default.
• W2149802606 cites W2048355240 @default.
• W2149802606 cites W2058911936 @default.
• W2149802606 cites W2062842057 @default.
• W2149802606 cites W2088711389 @default.
• W2149802606 cites W2095534724 @default.
• W2149802606 cites W2128635872 @default.
• W2149802606 cites W2313589426 @default.
• W2149802606 cites W2399132613 @default.
• W2149802606 cites W2410909496 @default.
• W2149802606 cites W2412928376 @default.
• W2149802606 cites W2417705998 @default.
• W2149802606 doi "https://doi.org/10.1080/095530099139809" @default.
• W2149802606 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10465370" @default.
• W2149802606 hasPublicationYear "1999" @default.
• W2149802606 type Work @default.
• W2149802606 sameAs 2149802606 @default.
• W2149802606 citedByCount "7" @default.
• W2149802606 countsByYear W21498026062012 @default.
• W2149802606 countsByYear W21498026062013 @default.
• W2149802606 crossrefType "journal-article" @default.
• W2149802606 hasAuthorship W2149802606A5008654635 @default.
• W2149802606 hasAuthorship W2149802606A5029195570 @default.
• W2149802606 hasAuthorship W2149802606A5073113433 @default.
• W2149802606 hasAuthorship W2149802606A5078888968 @default.
• W2149802606 hasAuthorship W2149802606A5085973884 @default.
• W2149802606 hasAuthorship W2149802606A5089441565 @default.
• W2149802606 hasConcept C104317684 @default.
• W2149802606 hasConcept C134935766 @default.
• W2149802606 hasConcept C143065580 @default.
• W2149802606 hasConcept C143425029 @default.
• W2149802606 hasConcept C147897179 @default.
• W2149802606 hasConcept C153911025 @default.
• W2149802606 hasConcept C2777755551 @default.
• W2149802606 hasConcept C2778575167 @default.
• W2149802606 hasConcept C502942594 @default.
• W2149802606 hasConcept C54355233 @default.
• W2149802606 hasConcept C552990157 @default.
• W2149802606 hasConcept C81885089 @default.
• W2149802606 hasConcept C86803240 @default.
• W2149802606 hasConceptScore W2149802606C104317684 @default.
• W2149802606 hasConceptScore W2149802606C134935766 @default.
• W2149802606 hasConceptScore W2149802606C143065580 @default.
• W2149802606 hasConceptScore W2149802606C143425029 @default.
• W2149802606 hasConceptScore W2149802606C147897179 @default.
• W2149802606 hasConceptScore W2149802606C153911025 @default.
• W2149802606 hasConceptScore W2149802606C2777755551 @default.
• W2149802606 hasConceptScore W2149802606C2778575167 @default.
• W2149802606 hasConceptScore W2149802606C502942594 @default.
• W2149802606 hasConceptScore W2149802606C54355233 @default.
• W2149802606 hasConceptScore W2149802606C552990157 @default.
• W2149802606 hasConceptScore W2149802606C81885089 @default.
• W2149802606 hasConceptScore W2149802606C86803240 @default.
• W2149802606 hasIssue "8" @default.
• W2149802606 hasLocation W21498026061 @default.
• W2149802606 hasLocation W21498026062 @default.
• W2149802606 hasOpenAccess W2149802606 @default.
• W2149802606 hasPrimaryLocation W21498026061 @default.
• W2149802606 hasRelatedWork W1626527928 @default.
• W2149802606 hasRelatedWork W2026746211 @default.
• W2149802606 hasRelatedWork W2030141157 @default.
• W2149802606 hasRelatedWork W2082928509 @default.
• W2149802606 hasRelatedWork W2088061849 @default.
• W2149802606 hasRelatedWork W2115731832 @default.
• W2149802606 hasRelatedWork W2157921288 @default.
• W2149802606 hasRelatedWork W2169830244 @default.
• W2149802606 hasRelatedWork W2397408366 @default.
• W2149802606 hasRelatedWork W2011173021 @default.
• W2149802606 hasVolume "75" @default.
• W2149802606 isParatext "false" @default.
• W2149802606 isRetracted "false" @default.

• next