FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149837516> ?p ?o ?g. }

• W2149837516 endingPage "1302" @default.
• W2149837516 startingPage "1290" @default.
• W2149837516 abstract "Noxious stimulation of spinal afferents inhibits primate spinothalamic tract (STT) neurons in segments distant from the region of afferent entry. Inhibitory effects of cardiopulmonary sympathetic afferent (CPSA) stimulation remain after C(1) transection but disappear with spinal transection between C(3) and C(7). We hypothesized that spinal inhibitory effects produced by CPSA stimulation are processed by neurons in C(1)-C(3) segments. One purpose of this study in anesthetized monkeys was to determine whether chemical activation of high cervical neurons reduced sacral STT cell responses to colorectal distension (CRD) and urinary bladder distension (UBD). First, effects and interactions of pelvic and cardiopulmonary visceral afferent inputs were determined in 10 monkeys on extracellular activity of sacral STT neurons recorded in deep dorsal horn. CRD and UBD increased activity in 95 and 91% of sacral STT neurons, respectively. CPSA and cardiopulmonary vagal stimulation decreased activity in 84 and 56% of STT neurons, respectively. CPSA stimulation decreased CRD-evoked activity in six of eight sacral STT neurons and decreased UBD-evoked activity in five of eight STT neurons tested. Excitatory amino acid application at C2 segment decreased CRD-evoked responses in 7 of 10 sacral STT neurons and decreased UBD-evoked responses in 9 of 12 STT neurons. The second purpose of this study was to examine responses of C(1)-C(3) descending propriospinal neurons to stimulation of cardiopulmonary afferent fibers. If C(1)-C(3) neurons process CPSA input to suppress STT transmission, then CPSA stimulation should excite C(1)-C(3) neurons with descending projections. Effects of thoracic vagus nerve stimulation also were examined. Vagal stimulation inhibits STT neurons in segments below C(3) but excites C(1)-C(3) STT neurons; we theorized that vagal inhibition of sensory transmission might relay in high cervical segments and, therefore, excite C(1)-C(3) descending propriospinal neurons. Extracellular discharge rate was recorded for C(1)-C(3) neurons antidromically activated from thoracic or lumbar spinal cord in 24 monkeys. CPSA stimulation increased activity of 16 of 45 neurons and inhibited one cell. Thoracic vagus stimulation increased activity of 20 of 43 neurons and inhibited one cell; stimulation of abdominal vagus fibers did not affect activity of six of six cells that were excited by thoracic vagal input. Mechanical stimulation of somatic fields excited 30 of 41 neurons tested. All neurons activated by visceral input received convergent somatic input from noxious pinch of somatic receptive fields that generally included the neck and upper body; 11 C(1)-C(3) propriospinal neurons did not respond to any afferent input examined. Results of these studies were consistent with the idea that modulation of spinal nociceptive transmission might involve neuronal connections in high cervical segments." @default.
• W2149837516 created "2016-06-24" @default.
• W2149837516 creator A5010304955 @default.
• W2149837516 creator A5012834397 @default.
• W2149837516 creator A5072284526 @default.
• W2149837516 creator A5081479423 @default.
• W2149837516 date "2002-03-01" @default.
• W2149837516 modified "2023-10-15" @default.
• W2149837516 title "Spinal Inhibitory Effects of Cardiopulmonary Afferent Inputs in Monkeys: Neuronal Processing in High Cervical Segments" @default.
• W2149837516 cites W1888857797 @default.
• W2149837516 cites W1946950710 @default.
• W2149837516 cites W1965026024 @default.
• W2149837516 cites W1966677629 @default.
• W2149837516 cites W1967764695 @default.
• W2149837516 cites W1968796143 @default.
• W2149837516 cites W1974486677 @default.
• W2149837516 cites W1975662189 @default.
• W2149837516 cites W1975681188 @default.
• W2149837516 cites W1976430391 @default.
• W2149837516 cites W1979456686 @default.
• W2149837516 cites W1982005210 @default.
• W2149837516 cites W1985438293 @default.
• W2149837516 cites W1988273041 @default.
• W2149837516 cites W1997760950 @default.
• W2149837516 cites W2006212856 @default.
• W2149837516 cites W2009559480 @default.
• W2149837516 cites W2013106094 @default.
• W2149837516 cites W2025195922 @default.
• W2149837516 cites W2027367566 @default.
• W2149837516 cites W2027481880 @default.
• W2149837516 cites W2035648992 @default.
• W2149837516 cites W2036419287 @default.
• W2149837516 cites W2037994619 @default.
• W2149837516 cites W2048776247 @default.
• W2149837516 cites W2049228132 @default.
• W2149837516 cites W2051340124 @default.
• W2149837516 cites W2053936471 @default.
• W2149837516 cites W2057688664 @default.
• W2149837516 cites W2059134632 @default.
• W2149837516 cites W2079796670 @default.
• W2149837516 cites W2092358120 @default.
• W2149837516 cites W2094689222 @default.
• W2149837516 cites W2095363158 @default.
• W2149837516 cites W2114727304 @default.
• W2149837516 cites W2115901151 @default.
• W2149837516 cites W2138512124 @default.
• W2149837516 cites W2157239778 @default.
• W2149837516 cites W2161123433 @default.
• W2149837516 cites W2170481101 @default.
• W2149837516 cites W2176807824 @default.
• W2149837516 cites W2189853014 @default.
• W2149837516 cites W2200343701 @default.
• W2149837516 cites W2220182884 @default.
• W2149837516 cites W2248855452 @default.
• W2149837516 cites W2256949214 @default.
• W2149837516 cites W2274260394 @default.
• W2149837516 cites W2323605690 @default.
• W2149837516 cites W2338423006 @default.
• W2149837516 cites W2344168060 @default.
• W2149837516 cites W2411853216 @default.
• W2149837516 cites W2908175543 @default.
• W2149837516 doi "https://doi.org/10.1152/jn.00079.2001" @default.
• W2149837516 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11877503" @default.
• W2149837516 hasPublicationYear "2002" @default.
• W2149837516 type Work @default.
• W2149837516 sameAs 2149837516 @default.
• W2149837516 citedByCount "41" @default.
• W2149837516 countsByYear W21498375162012 @default.
• W2149837516 countsByYear W21498375162014 @default.
• W2149837516 countsByYear W21498375162015 @default.
• W2149837516 countsByYear W21498375162017 @default.
• W2149837516 countsByYear W21498375162018 @default.
• W2149837516 countsByYear W21498375162019 @default.
• W2149837516 countsByYear W21498375162020 @default.
• W2149837516 countsByYear W21498375162022 @default.
• W2149837516 crossrefType "journal-article" @default.
• W2149837516 hasAuthorship W2149837516A5010304955 @default.
• W2149837516 hasAuthorship W2149837516A5012834397 @default.
• W2149837516 hasAuthorship W2149837516A5072284526 @default.
• W2149837516 hasAuthorship W2149837516A5081479423 @default.
• W2149837516 hasConcept C112592302 @default.
• W2149837516 hasConcept C126322002 @default.
• W2149837516 hasConcept C15490471 @default.
• W2149837516 hasConcept C169760540 @default.
• W2149837516 hasConcept C170493617 @default.
• W2149837516 hasConcept C17077164 @default.
• W2149837516 hasConcept C185592680 @default.
• W2149837516 hasConcept C24998067 @default.
• W2149837516 hasConcept C2776625112 @default.
• W2149837516 hasConcept C2778222838 @default.
• W2149837516 hasConcept C2780775167 @default.
• W2149837516 hasConcept C42219234 @default.
• W2149837516 hasConcept C71924100 @default.
• W2149837516 hasConcept C74254510 @default.
• W2149837516 hasConcept C86803240 @default.
• W2149837516 hasConceptScore W2149837516C112592302 @default.
• W2149837516 hasConceptScore W2149837516C126322002 @default.
• W2149837516 hasConceptScore W2149837516C15490471 @default.

• next