FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149886980> ?p ?o ?g. }

• W2149886980 endingPage "687" @default.
• W2149886980 startingPage "665" @default.
• W2149886980 abstract "HRP has been used as a cytochemical marker for a sterelogic analysis of pinocytic vesicles and secondary lysosomes in cultivated macrophages and L cells. Evidence is presented that the diaminobenzidine technique (a) detects all vaculoes containing encyme and (b) distinguishes between incoming pinocytic vesicles and those which have fused with pre-existing lysosomes to form secondary lososomes. The HRP reactive pinocytic vesicle spaces fills completely within 5 min after exposure to enzyme, while the secondary lysosome compartment is saturated in 45--60 min. The size distribution of sectioned (profile) vaculoe diameters was measured at equilibrium and converted to actual (spherical) dimensions using a technique modified from Dr. S. D. Wicksell. The most important findings in this study have to do with the rate at which pinocytosed fluid and surface membrane move into the cell and on their subsequent fate. Each minute macrophages form at least 125 pinocytic vesicles having a fractional vol of 0.43% of the cell's volume and a fractional area of 3.1% of the cell's surface area. The fractional volume and surface area flux rates for L cells were 0.05% and 0.8% per minute respectively. Macrophages and L cells thus interiorize the equivalent of their cell surface area every 33 and 125 min. During a 3-period, the size of the secondary lysosome compartment remains constant and represents 2.5% of the cell volume and 18% of the surface area. Each hour, therefore, the volume and surface area of incoming vesicles is 10 times greater than the dimensions of the secondary lysosomes in both macrophages and L cells. This implies a rapid reduction in vesicle size during the formation of the secondary lysosome and the egress of pinocytosed fluid from the vacuole and the cell. In addition, we postulate that membrane components of the vacuole are subsequently recycled back to the cell surface." @default.
• W2149886980 created "2016-06-24" @default.
• W2149886980 creator A5021509115 @default.
• W2149886980 creator A5066273096 @default.
• W2149886980 creator A5089964758 @default.
• W2149886980 date "1976-03-01" @default.
• W2149886980 modified "2023-10-15" @default.
• W2149886980 title "Membrane flow during pinocytosis. A stereologic analysis." @default.
• W2149886980 cites W1566747358 @default.
• W2149886980 cites W1599717497 @default.
• W2149886980 cites W1775749144 @default.
• W2149886980 cites W1976572444 @default.
• W2149886980 cites W1992589107 @default.
• W2149886980 cites W2003022694 @default.
• W2149886980 cites W2006387884 @default.
• W2149886980 cites W2008101816 @default.
• W2149886980 cites W2011195518 @default.
• W2149886980 cites W2013340592 @default.
• W2149886980 cites W2016418167 @default.
• W2149886980 cites W2017461569 @default.
• W2149886980 cites W2029463562 @default.
• W2149886980 cites W2038988865 @default.
• W2149886980 cites W2040671940 @default.
• W2149886980 cites W2041894836 @default.
• W2149886980 cites W2057706200 @default.
• W2149886980 cites W2062070852 @default.
• W2149886980 cites W2062329380 @default.
• W2149886980 cites W2067184583 @default.
• W2149886980 cites W2073910977 @default.
• W2149886980 cites W2077078597 @default.
• W2149886980 cites W2077423799 @default.
• W2149886980 cites W2081473302 @default.
• W2149886980 cites W2084767442 @default.
• W2149886980 cites W2092746228 @default.
• W2149886980 cites W2093331057 @default.
• W2149886980 cites W2102040847 @default.
• W2149886980 cites W2109790584 @default.
• W2149886980 cites W2112128403 @default.
• W2149886980 cites W2114005636 @default.
• W2149886980 cites W2117233739 @default.
• W2149886980 cites W2125744564 @default.
• W2149886980 cites W2140358693 @default.
• W2149886980 cites W2145780410 @default.
• W2149886980 cites W2159974449 @default.
• W2149886980 cites W2169004846 @default.
• W2149886980 cites W2172095199 @default.
• W2149886980 cites W2313662643 @default.
• W2149886980 cites W2316024927 @default.
• W2149886980 cites W2327484062 @default.
• W2149886980 cites W2419482883 @default.
• W2149886980 doi "https://doi.org/10.1083/jcb.68.3.665" @default.
• W2149886980 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2109655" @default.
• W2149886980 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1030706" @default.
• W2149886980 hasPublicationYear "1976" @default.
• W2149886980 type Work @default.
• W2149886980 sameAs 2149886980 @default.
• W2149886980 citedByCount "612" @default.
• W2149886980 countsByYear W21498869802012 @default.
• W2149886980 countsByYear W21498869802013 @default.
• W2149886980 countsByYear W21498869802014 @default.
• W2149886980 countsByYear W21498869802015 @default.
• W2149886980 countsByYear W21498869802016 @default.
• W2149886980 countsByYear W21498869802017 @default.
• W2149886980 countsByYear W21498869802018 @default.
• W2149886980 countsByYear W21498869802019 @default.
• W2149886980 countsByYear W21498869802020 @default.
• W2149886980 countsByYear W21498869802021 @default.
• W2149886980 countsByYear W21498869802022 @default.
• W2149886980 countsByYear W21498869802023 @default.
• W2149886980 crossrefType "journal-article" @default.
• W2149886980 hasAuthorship W2149886980A5021509115 @default.
• W2149886980 hasAuthorship W2149886980A5066273096 @default.
• W2149886980 hasAuthorship W2149886980A5089964758 @default.
• W2149886980 hasBestOaLocation W21498869801 @default.
• W2149886980 hasConcept C111368507 @default.
• W2149886980 hasConcept C121332964 @default.
• W2149886980 hasConcept C12554922 @default.
• W2149886980 hasConcept C127313418 @default.
• W2149886980 hasConcept C130316041 @default.
• W2149886980 hasConcept C1491633281 @default.
• W2149886980 hasConcept C181199279 @default.
• W2149886980 hasConcept C203635412 @default.
• W2149886980 hasConcept C20556612 @default.
• W2149886980 hasConcept C2780216420 @default.
• W2149886980 hasConcept C28005876 @default.
• W2149886980 hasConcept C40017333 @default.
• W2149886980 hasConcept C41625074 @default.
• W2149886980 hasConcept C55493867 @default.
• W2149886980 hasConcept C62520636 @default.
• W2149886980 hasConcept C86803240 @default.
• W2149886980 hasConceptScore W2149886980C111368507 @default.
• W2149886980 hasConceptScore W2149886980C121332964 @default.
• W2149886980 hasConceptScore W2149886980C12554922 @default.
• W2149886980 hasConceptScore W2149886980C127313418 @default.
• W2149886980 hasConceptScore W2149886980C130316041 @default.
• W2149886980 hasConceptScore W2149886980C1491633281 @default.
• W2149886980 hasConceptScore W2149886980C181199279 @default.
• W2149886980 hasConceptScore W2149886980C203635412 @default.

• next