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• W2149901689 abstract "The retinoblastoma protein (RB) represses RNA polymerase III transcription effectively both in vivo and in vitro. Here we demonstrate that the general transcription factors snRNA-activating protein complex (SNAPc) and TATA binding protein (TBP) are important for RB repression of human U6 snRNA gene transcription by RNA polymerase III. RB is associated with SNAPc as detected by both coimmunoprecipitation of endogenous RB with SNAPc and cofractionation of RB and SNAPc during chromatographic purification. RB also interacts with two SNAPc subunits, SNAP43 and SNAP50. TBP or a combination of TBP and SNAPcrestores efficient U6 transcription from RB-treated extracts, indicating that TBP is also involved in RB regulation. In contrast, the TBP-containing complex TFIIIB restores adenovirus VAI but not human U6 transcription in RB-treated extracts, suggesting that TFIIIB is important for RB regulation of tRNA-like genes. These results suggest that different classes of RNA polymerase III-transcribed genes have distinct general transcription factor requirements for repression by RB." @default.
• W2149901689 created "2016-06-24" @default.
• W2149901689 creator A5018315675 @default.
• W2149901689 creator A5033635354 @default.
• W2149901689 creator A5041957172 @default.
• W2149901689 date "2000-12-01" @default.
• W2149901689 modified "2023-09-27" @default.
• W2149901689 title "The Retinoblastoma Tumor Suppressor Protein Targets Distinct General Transcription Factors To Regulate RNA Polymerase III Gene Expression" @default.
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• W2149901689 cites W1665024321 @default.
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• W2149901689 cites W1750653145 @default.
• W2149901689 cites W179941649 @default.
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• W2149901689 doi "https://doi.org/10.1128/mcb.20.24.9182-9191.2000" @default.
• W2149901689 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/102176" @default.
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