Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149953008> ?p ?o ?g. }
- W2149953008 endingPage "1941" @default.
- W2149953008 startingPage "1931" @default.
- W2149953008 abstract "Animal models have been used for a number of decades to study arthritis and have contributed greatly to unravelling mechanisms of pathogenesis and validating new targets for treatment. All animal models have sets of limitations and over the years there has been natural refinement of existing models as well as creation of new ones. The success of genetic modification in mice has fuelled an exponential increase in the use of murine models for arthritis research and has significantly increased our understanding of disease processes. This review focuses on those rodent models of RA and OA that have current utility and are widely used by the research community. We highlight the subtle but important differences in existing models by positioning them on a pathogenesis map whereby model selection is determined by the specific aspect of disease to be studied. We discuss the evolving challenges in in vivo arthritis studies and our perceived gaps for future new model development. The document includes technical and cost implications of performing the described models, and the ethical considerations of such approaches." @default.
- W2149953008 created "2016-06-24" @default.
- W2149953008 creator A5018096937 @default.
- W2149953008 creator A5050302517 @default.
- W2149953008 creator A5051046892 @default.
- W2149953008 creator A5051609124 @default.
- W2149953008 creator A5086744726 @default.
- W2149953008 date "2012-03-16" @default.
- W2149953008 modified "2023-10-14" @default.
- W2149953008 title "Mapping pathogenesis of arthritis through small animal models" @default.
- W2149953008 cites W132781887 @default.
- W2149953008 cites W1521993208 @default.
- W2149953008 cites W1859919406 @default.
- W2149953008 cites W1965245788 @default.
- W2149953008 cites W1967913927 @default.
- W2149953008 cites W1969830786 @default.
- W2149953008 cites W1971890827 @default.
- W2149953008 cites W1972426822 @default.
- W2149953008 cites W1975554070 @default.
- W2149953008 cites W1975698703 @default.
- W2149953008 cites W1982018212 @default.
- W2149953008 cites W1983227824 @default.
- W2149953008 cites W1983579606 @default.
- W2149953008 cites W1983811609 @default.
- W2149953008 cites W1986666248 @default.
- W2149953008 cites W1987224476 @default.
- W2149953008 cites W1995577585 @default.
- W2149953008 cites W1997475807 @default.
- W2149953008 cites W2005308135 @default.
- W2149953008 cites W2007033032 @default.
- W2149953008 cites W2008255482 @default.
- W2149953008 cites W2011227409 @default.
- W2149953008 cites W2016004071 @default.
- W2149953008 cites W2017869529 @default.
- W2149953008 cites W2019639349 @default.
- W2149953008 cites W2022939181 @default.
- W2149953008 cites W2024347439 @default.
- W2149953008 cites W2032257487 @default.
- W2149953008 cites W2035959842 @default.
- W2149953008 cites W2043304304 @default.
- W2149953008 cites W2046158787 @default.
- W2149953008 cites W2046720655 @default.
- W2149953008 cites W2046957298 @default.
- W2149953008 cites W2050833972 @default.
- W2149953008 cites W2056909025 @default.
- W2149953008 cites W2060951121 @default.
- W2149953008 cites W2062522737 @default.
- W2149953008 cites W2062998718 @default.
- W2149953008 cites W2064958651 @default.
- W2149953008 cites W2068952692 @default.
- W2149953008 cites W2070871300 @default.
- W2149953008 cites W2071718640 @default.
- W2149953008 cites W2072811404 @default.
- W2149953008 cites W2076642520 @default.
- W2149953008 cites W2077347520 @default.
- W2149953008 cites W2080824635 @default.
- W2149953008 cites W2085853581 @default.
- W2149953008 cites W2093740273 @default.
- W2149953008 cites W2094617720 @default.
- W2149953008 cites W2099903298 @default.
- W2149953008 cites W2102343281 @default.
- W2149953008 cites W2102703734 @default.
- W2149953008 cites W2104916764 @default.
- W2149953008 cites W2107005433 @default.
- W2149953008 cites W2107951685 @default.
- W2149953008 cites W2108568436 @default.
- W2149953008 cites W2109216202 @default.
- W2149953008 cites W2116616841 @default.
- W2149953008 cites W2119071799 @default.
- W2149953008 cites W2119381090 @default.
- W2149953008 cites W2120312541 @default.
- W2149953008 cites W2123001296 @default.
- W2149953008 cites W2124563490 @default.
- W2149953008 cites W2129389823 @default.
- W2149953008 cites W2130979463 @default.
- W2149953008 cites W2132631648 @default.
- W2149953008 cites W2133032095 @default.
- W2149953008 cites W2137527329 @default.
- W2149953008 cites W2137530456 @default.
- W2149953008 cites W214936949 @default.
- W2149953008 cites W2153607816 @default.
- W2149953008 cites W2154362046 @default.
- W2149953008 cites W2154519842 @default.
- W2149953008 cites W2156900805 @default.
- W2149953008 cites W2159196790 @default.
- W2149953008 cites W2163274985 @default.
- W2149953008 cites W2165431421 @default.
- W2149953008 cites W2168221175 @default.
- W2149953008 cites W2331507609 @default.
- W2149953008 cites W4296816736 @default.
- W2149953008 doi "https://doi.org/10.1093/rheumatology/kes035" @default.
- W2149953008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22427408" @default.
- W2149953008 hasPublicationYear "2012" @default.
- W2149953008 type Work @default.
- W2149953008 sameAs 2149953008 @default.
- W2149953008 citedByCount "99" @default.
- W2149953008 countsByYear W21499530082012 @default.
- W2149953008 countsByYear W21499530082013 @default.