Matches in SemOpenAlex for { <https://semopenalex.org/work/W2150031549> ?p ?o ?g. }
- W2150031549 endingPage "2508" @default.
- W2150031549 startingPage "2504" @default.
- W2150031549 abstract "ABSTRACT Because congenital toxoplasmosis is almost solely the result of maternal infection acquired during gestation, it is critical to determine whether infection during pregnancy has occurred. In the United States, definitive diagnosis of the acute infection and the time of its occurrence have been compromised by a lack of systematic screening and the fact that only a single serum sample is submitted for testing. In studies in Europe, and depending on the method used, the demonstration of high-avidity immunoglobulin G (IgG) toxoplasma antibodies has been shown to exclude infection having occurred in the first 3 to 5 months of pregnancy. We investigated the usefulness of determining the avidity of IgG toxoplasma antibodies with a VIDAS kit (herein referred to as the VIDAS Toxo-IgG avidity kit, the VIDAS kit essentially rules out acute infection having occurred within the 4 prior months) in the setting of a reference serology laboratory in the United States. Sera (132 samples) from 132 women in the first 16 weeks of pregnancy were chosen because at least one test in the toxoplasma serological profile (TSP) suggested or was equivocal for a recently acquired infection. High-avidity antibodies were demonstrated in 75% of 99 sera positive with the IgM enzyme-linked immunosorbent assay (ELISA) and 31.3% of 16 sera with acute TSP results. A significant percentage of sera with equivocal results wtih the IgM ELISA or TSP also had high-avidity test results. Of 39 women for whom treatment with spiramycin had been suggested to attempt to prevent congenital transmission, 19 (48.7%) had high-avidity antibodies. These findings highlight the value of the VIDAS IgG avidity kit when used in combination with the TSP to exclude recent infection, especially when only a single serum sample is available." @default.
- W2150031549 created "2016-06-24" @default.
- W2150031549 creator A5012534523 @default.
- W2150031549 creator A5015192105 @default.
- W2150031549 creator A5051195358 @default.
- W2150031549 creator A5061082548 @default.
- W2150031549 creator A5068801478 @default.
- W2150031549 date "2002-07-01" @default.
- W2150031549 modified "2023-09-27" @default.
- W2150031549 title "VIDAS Test for Avidity of <i>Toxoplasma</i> -Specific Immunoglobulin G for Confirmatory Testing of Pregnant Women" @default.
- W2150031549 cites W1533597960 @default.
- W2150031549 cites W1778605054 @default.
- W2150031549 cites W1899022156 @default.
- W2150031549 cites W1947083210 @default.
- W2150031549 cites W1948313021 @default.
- W2150031549 cites W1971916662 @default.
- W2150031549 cites W1977143504 @default.
- W2150031549 cites W1989091564 @default.
- W2150031549 cites W2024251697 @default.
- W2150031549 cites W2041941863 @default.
- W2150031549 cites W2051133670 @default.
- W2150031549 cites W2067157751 @default.
- W2150031549 cites W2099189598 @default.
- W2150031549 cites W2109627543 @default.
- W2150031549 cites W2112990453 @default.
- W2150031549 cites W2113380727 @default.
- W2150031549 cites W2118144692 @default.
- W2150031549 cites W2136260293 @default.
- W2150031549 cites W2148735882 @default.
- W2150031549 cites W2150589746 @default.
- W2150031549 doi "https://doi.org/10.1128/jcm.40.7.2504-2508.2002" @default.
- W2150031549 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/120549" @default.
- W2150031549 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12089270" @default.
- W2150031549 hasPublicationYear "2002" @default.
- W2150031549 type Work @default.
- W2150031549 sameAs 2150031549 @default.
- W2150031549 citedByCount "123" @default.
- W2150031549 countsByYear W21500315492012 @default.
- W2150031549 countsByYear W21500315492013 @default.
- W2150031549 countsByYear W21500315492014 @default.
- W2150031549 countsByYear W21500315492015 @default.
- W2150031549 countsByYear W21500315492016 @default.
- W2150031549 countsByYear W21500315492017 @default.
- W2150031549 countsByYear W21500315492018 @default.
- W2150031549 countsByYear W21500315492019 @default.
- W2150031549 countsByYear W21500315492020 @default.
- W2150031549 countsByYear W21500315492021 @default.
- W2150031549 countsByYear W21500315492022 @default.
- W2150031549 countsByYear W21500315492023 @default.
- W2150031549 crossrefType "journal-article" @default.
- W2150031549 hasAuthorship W2150031549A5012534523 @default.
- W2150031549 hasAuthorship W2150031549A5015192105 @default.
- W2150031549 hasAuthorship W2150031549A5051195358 @default.
- W2150031549 hasAuthorship W2150031549A5061082548 @default.
- W2150031549 hasAuthorship W2150031549A5068801478 @default.
- W2150031549 hasBestOaLocation W21500315492 @default.
- W2150031549 hasConcept C159047783 @default.
- W2150031549 hasConcept C159654299 @default.
- W2150031549 hasConcept C179223381 @default.
- W2150031549 hasConcept C203014093 @default.
- W2150031549 hasConcept C2776553844 @default.
- W2150031549 hasConcept C2778062946 @default.
- W2150031549 hasConcept C2779172262 @default.
- W2150031549 hasConcept C2779234561 @default.
- W2150031549 hasConcept C2780206985 @default.
- W2150031549 hasConcept C2780898057 @default.
- W2150031549 hasConcept C45189115 @default.
- W2150031549 hasConcept C46973012 @default.
- W2150031549 hasConcept C501593827 @default.
- W2150031549 hasConcept C54355233 @default.
- W2150031549 hasConcept C71924100 @default.
- W2150031549 hasConcept C86803240 @default.
- W2150031549 hasConcept C89423630 @default.
- W2150031549 hasConceptScore W2150031549C159047783 @default.
- W2150031549 hasConceptScore W2150031549C159654299 @default.
- W2150031549 hasConceptScore W2150031549C179223381 @default.
- W2150031549 hasConceptScore W2150031549C203014093 @default.
- W2150031549 hasConceptScore W2150031549C2776553844 @default.
- W2150031549 hasConceptScore W2150031549C2778062946 @default.
- W2150031549 hasConceptScore W2150031549C2779172262 @default.
- W2150031549 hasConceptScore W2150031549C2779234561 @default.
- W2150031549 hasConceptScore W2150031549C2780206985 @default.
- W2150031549 hasConceptScore W2150031549C2780898057 @default.
- W2150031549 hasConceptScore W2150031549C45189115 @default.
- W2150031549 hasConceptScore W2150031549C46973012 @default.
- W2150031549 hasConceptScore W2150031549C501593827 @default.
- W2150031549 hasConceptScore W2150031549C54355233 @default.
- W2150031549 hasConceptScore W2150031549C71924100 @default.
- W2150031549 hasConceptScore W2150031549C86803240 @default.
- W2150031549 hasConceptScore W2150031549C89423630 @default.
- W2150031549 hasIssue "7" @default.
- W2150031549 hasLocation W21500315491 @default.
- W2150031549 hasLocation W21500315492 @default.
- W2150031549 hasLocation W21500315493 @default.
- W2150031549 hasOpenAccess W2150031549 @default.
- W2150031549 hasPrimaryLocation W21500315491 @default.
- W2150031549 hasRelatedWork W1569996386 @default.
- W2150031549 hasRelatedWork W1989091564 @default.