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- W2150033361 abstract "Aflatoxin B1 (AFB1) has been consistently shown to be a potent mutagen and is a liver carcinogen in humans and a wide range of animal species. The Fisher rat appears to be the most sensitive animal model. Dose-response modelling results in a BMDL(10) of 250 ng/kg-bw/d. Estimates of mean dietary exposure estimates were 0.4 ng/kg-bw/d and 2.6 ng/kg-bw/d, representing regions with low and high exposure, respectively. The MOEs for mean exposure therefore range from 100 to 600." @default.
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- W2150033361 date "2010-01-01" @default.
- W2150033361 modified "2023-09-26" @default.
- W2150033361 title "Application of the margin of exposure (MoE) approach to substances in food that are genotoxic and carcinogenic" @default.
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- W2150033361 doi "https://doi.org/10.1016/j.fct.2009.10.037" @default.
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