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• W2150076013 abstract "Development of highly sensitive diagnostic nanoprobe for cancer imaging based on surface-enhanced Raman scattering (SERS) platform.Synthesis of novel squaraine dyes as a Raman signature molecule denoted as lipoic-squaraine-lipoic (LSL), propyl-squaraine-lipoic (PSL) and propyl-squaraine-propyl (PSP). The SERS-nanotag constructed with a Raman signature molecule which is attached on gold nanoparticle and further encapsulated with heterofunctionalized PEG. Antibody conjugation with best SERS-nanotag for target specific recognition.SERS nanotag Au-LSL-PEG showed significant signal intensity and remarkable stability. Anti-EGF receptor and Her2-conjugated Au-LSL-PEG-nanotag were successfully applied for selective recognition of cancer cells like A549, OSCC and MCF7.The newly developed SERS-nanotag Au-LSL-PEG serves as a valuable tool for diagnostic detection of cancer cells, and may find potential applications for cancer screening in real patient samples." @default.
• W2150076013 created "2016-06-24" @default.
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• W2150076013 date "2015-03-01" @default.
• W2150076013 modified "2023-09-27" @default.
• W2150076013 title "New insight of squaraine-based biocompatible surface-enhanced Raman scattering nanotag for cancer-cell imaging" @default.
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• W2150076013 doi "https://doi.org/10.2217/nnm.14.125" @default.
• W2150076013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25723090" @default.
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