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- W2150103669 abstract "Ticks are ectoparasites that cause dermatologic disease both directly through physical trauma to the skin, salivary secretions, or remnant body parts, and indirectly through transmission of disease. Lyme disease, Rocky Mountain spotted fever, tularemia, and babesiosis are known tick-transmitted diseases. The histopathology related to a primary tick bite, similar to other arthropod bites, classically consists of a perivascular infiltrate composed of lymphocytes, neutrophils, histiocytes, plasma cells, and eosinophils in varying amounts. We describe five patients with a novel histologic reaction to embedded tick parts., Each case demonstrates a thrombotic vasculopathy consisting of intraluminal eosinophilic deposits that stain strongly with Periodic acid Schiff stain. The adjacent tissue shows dermal necrosis with surrounding interstitial to diffuse dermal neutrophilic inflammation. We postulate that diffuse dermal nutrophilic infiltrates in association with thrombogenic vasculopathy is an unusual histologic picture of tick bite reactions that may be attributable to remnant tick parts." @default.
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- W2150103669 date "2008-06-28" @default.
- W2150103669 modified "2023-09-24" @default.
- W2150103669 title "Thrombogenic Vasculopathy and Interstitial to Diffuse Dermal Neutrophilic Inflammation as a Histologic Manifestation of Tick Bite Reaction" @default.
- W2150103669 doi "https://doi.org/10.1111/j.0303-6987.2005.320fg.x" @default.
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