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• W2150147498 endingPage "2083" @default.
• W2150147498 startingPage "2076" @default.
• W2150147498 abstract "Riboswitches are natural RNA-based genetic switches that sense small-molecule metabolites and regulate in response the expression of the corresponding metabolic genes. Within the last years, several engineered riboswitches have been developed that act on various stages of gene expression. These switches can be engineered to respond to any ligand of choice and are therefore of great interest for synthetic biology. In this review, we present an overview of engineered riboswitches and discuss their application in conditional gene expression systems. We will provide structural and mechanistic insights and point out problems and recent trends in the development of engineered riboswitches." @default.
• W2150147498 created "2016-06-24" @default.
• W2150147498 creator A5060602614 @default.
• W2150147498 creator A5076651173 @default.
• W2150147498 date "2012-02-28" @default.
• W2150147498 modified "2023-10-14" @default.
• W2150147498 title "Engineered riboswitches: Expanding researchers' toolbox with synthetic RNA regulators" @default.
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• W2150147498 doi "https://doi.org/10.1016/j.febslet.2012.02.038" @default.
• W2150147498 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22710175" @default.
• W2150147498 hasPublicationYear "2012" @default.
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