Matches in SemOpenAlex for { <https://semopenalex.org/work/W2150167237> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2150167237 endingPage "18" @default.
- W2150167237 startingPage "18" @default.
- W2150167237 abstract "Acute myelogeneous leukemia (AML) is a malignancy of the hematopoietic stem cells, for which cytogenetic analysis is still one of the most important diagnostic and prognostic tools. Still, we are far away from having seen and described all possible genetic changes associated with this kind of acquired disease. Bone marrow cells of a female patient with clinical diagnoses of AML and immunophenotypically confirmed AML-M4 were studied by GTG-banding. The later was not able to resolve all karyotypic changes and the complex karyotype was characterized in more detail by fluorescence in situ hybridization (FISH) and array-proven multicolor banding (aMCB). To the best of our knowledge, the present case is the only one ever seen with a del(5)(q14q34), a der(17)t(4;17)(p13;p13), a del(2)(p23), a der(4)t(4;7)(p13;q11.23), a der(22)t(11;22)(q23;q11.2) and two complex rearranged chromosomes 11 involving chromosomes 7 and 22 as well as 2. The yet unreported breakpoints observed in this case seem to be correlated with an adverse prognosis. Overall, molecular cytogenetic studies are suited best for identification and characterization of chromosomal rearrangements in acute leukemia and single case reports as well as large scale studies are necessary to provide further insides in karyotypic changes taking place in human malignancies." @default.
- W2150167237 created "2016-06-24" @default.
- W2150167237 creator A5020245840 @default.
- W2150167237 creator A5032147152 @default.
- W2150167237 creator A5084512090 @default.
- W2150167237 creator A5085793967 @default.
- W2150167237 date "2013-01-01" @default.
- W2150167237 modified "2023-10-15" @default.
- W2150167237 title "A de novo acute myeloid leukemia (AML-M4) case with a complex karyotype and yet unreported breakpoints" @default.
- W2150167237 cites W1964323527 @default.
- W2150167237 cites W1970925222 @default.
- W2150167237 cites W1971885624 @default.
- W2150167237 cites W1992726393 @default.
- W2150167237 cites W2053487253 @default.
- W2150167237 cites W2076426515 @default.
- W2150167237 cites W2084283720 @default.
- W2150167237 cites W2091129902 @default.
- W2150167237 cites W2093845572 @default.
- W2150167237 cites W2107398329 @default.
- W2150167237 cites W2109065151 @default.
- W2150167237 cites W2116858301 @default.
- W2150167237 cites W2119967034 @default.
- W2150167237 cites W2147213204 @default.
- W2150167237 cites W2148047805 @default.
- W2150167237 cites W2150113701 @default.
- W2150167237 cites W2164238912 @default.
- W2150167237 cites W2165811446 @default.
- W2150167237 doi "https://doi.org/10.1186/1755-8166-6-18" @default.
- W2150167237 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3658984" @default.
- W2150167237 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23641812" @default.
- W2150167237 hasPublicationYear "2013" @default.
- W2150167237 type Work @default.
- W2150167237 sameAs 2150167237 @default.
- W2150167237 citedByCount "4" @default.
- W2150167237 countsByYear W21501672372013 @default.
- W2150167237 countsByYear W21501672372016 @default.
- W2150167237 countsByYear W21501672372020 @default.
- W2150167237 crossrefType "journal-article" @default.
- W2150167237 hasAuthorship W2150167237A5020245840 @default.
- W2150167237 hasAuthorship W2150167237A5032147152 @default.
- W2150167237 hasAuthorship W2150167237A5084512090 @default.
- W2150167237 hasAuthorship W2150167237A5085793967 @default.
- W2150167237 hasBestOaLocation W21501672371 @default.
- W2150167237 hasConcept C104317684 @default.
- W2150167237 hasConcept C142724271 @default.
- W2150167237 hasConcept C174475383 @default.
- W2150167237 hasConcept C206936463 @default.
- W2150167237 hasConcept C2777542201 @default.
- W2150167237 hasConcept C2778461978 @default.
- W2150167237 hasConcept C2778729363 @default.
- W2150167237 hasConcept C2779282312 @default.
- W2150167237 hasConcept C2779399171 @default.
- W2150167237 hasConcept C30481170 @default.
- W2150167237 hasConcept C502942594 @default.
- W2150167237 hasConcept C53226629 @default.
- W2150167237 hasConcept C54355233 @default.
- W2150167237 hasConcept C71924100 @default.
- W2150167237 hasConcept C86803240 @default.
- W2150167237 hasConceptScore W2150167237C104317684 @default.
- W2150167237 hasConceptScore W2150167237C142724271 @default.
- W2150167237 hasConceptScore W2150167237C174475383 @default.
- W2150167237 hasConceptScore W2150167237C206936463 @default.
- W2150167237 hasConceptScore W2150167237C2777542201 @default.
- W2150167237 hasConceptScore W2150167237C2778461978 @default.
- W2150167237 hasConceptScore W2150167237C2778729363 @default.
- W2150167237 hasConceptScore W2150167237C2779282312 @default.
- W2150167237 hasConceptScore W2150167237C2779399171 @default.
- W2150167237 hasConceptScore W2150167237C30481170 @default.
- W2150167237 hasConceptScore W2150167237C502942594 @default.
- W2150167237 hasConceptScore W2150167237C53226629 @default.
- W2150167237 hasConceptScore W2150167237C54355233 @default.
- W2150167237 hasConceptScore W2150167237C71924100 @default.
- W2150167237 hasConceptScore W2150167237C86803240 @default.
- W2150167237 hasIssue "1" @default.
- W2150167237 hasLocation W21501672371 @default.
- W2150167237 hasLocation W21501672372 @default.
- W2150167237 hasLocation W21501672373 @default.
- W2150167237 hasLocation W21501672374 @default.
- W2150167237 hasOpenAccess W2150167237 @default.
- W2150167237 hasPrimaryLocation W21501672371 @default.
- W2150167237 hasRelatedWork W1998796056 @default.
- W2150167237 hasRelatedWork W2006614657 @default.
- W2150167237 hasRelatedWork W2013106560 @default.
- W2150167237 hasRelatedWork W2032744925 @default.
- W2150167237 hasRelatedWork W2075866438 @default.
- W2150167237 hasRelatedWork W2088648042 @default.
- W2150167237 hasRelatedWork W2341129887 @default.
- W2150167237 hasRelatedWork W2360679935 @default.
- W2150167237 hasRelatedWork W27222924 @default.
- W2150167237 hasRelatedWork W2784463562 @default.
- W2150167237 hasVolume "6" @default.
- W2150167237 isParatext "false" @default.
- W2150167237 isRetracted "false" @default.
- W2150167237 magId "2150167237" @default.
- W2150167237 workType "article" @default.