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• W2150254328 abstract "ABSTRACT Pseudomonas aeruginosa clinical isolate CY-1, which was resistant to ceftazidime, harbored a conjugative ca. 250-kb plasmid that contained a class 1 integron with two gene cassettes encoding OXA-32, an OXA-2- type β-lactamase, and the aminoglycoside acetyltransferase AAC(6′)Ib 9 . OXA-32 differed from OXA-2 by an Leu169Ile amino acid substitution (class D numbering). Site-directed mutagenesis established that Ile169 is responsible for resistance to ceftazidime but not to cefotaxime." @default.
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• W2150254328 date "2002-02-01" @default.
• W2150254328 modified "2023-09-26" @default.
• W2150254328 title "Integron-Located oxa-32 Gene Cassette Encoding an Extended-Spectrum Variant of OXA-2 β-Lactamase from Pseudomonas aeruginosa" @default.
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• W2150254328 doi "https://doi.org/10.1128/aac.46.2.566-569.2002" @default.
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