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- W2150363202 abstract "A convenient synthesis of some new 1,4-disubstituted 1,2,3-bistriazoles (3a–3f, 4a–4f, 6a–6b, 7a–7b) is reported via copper(I)-catalyzed Huisgen 1,3-dipolar cycloaddition of various terminal alkynes with 1,4-bis(azidomethyl)benzene and 1,6-diazidohexane. The synthesized compounds were characterized by spectral techniques including infrared, 1H NMR, 13C NMR, and high-resolution mass spectrometry and tested in vitro for antimicrobial potential against Bacillus subtilis and Staphylococcus aureus (Gram-positive bacteria), Pseudomonas aeruginosa and Escherichia coli (Gram-negative bacteria), and Candida albicans and Aspergillus niger (fungi). Among the synthesized 1,4-disubstituted 1,2,3-bistriazoles, compounds 6a, 6b, and 7b displayed excellent antimicrobial potential against most of the tested strains." @default.
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- W2150363202 date "2015-07-17" @default.
- W2150363202 modified "2023-09-25" @default.
- W2150363202 title "Synthesis, Characterization, and Antimicrobial Potential of Some 1,4-Disubstituted 1,2,3-Bistriazoles" @default.
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- W2150363202 doi "https://doi.org/10.1080/00397911.2015.1056796" @default.
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