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- W2150460698 abstract "ortho-Acylation attempt of benzenesulfonamide afforded the corresponding hemiaminal as major product. The in situ reduction of the reaction mixture, reported herein, directly provided 2-hydroxyalkyl benzenesulfonamide, an important pharmacophoric element for designing drug-like scaffolds. Its application is demonstrated through designing a novel series of 1,5-diarylpyrazoles for cyclooxygenase-2 (COX-2) inhibition." @default.
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- W2150460698 date "2007-04-01" @default.
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- W2150460698 title "Pharmacophoric 2-hydroxyalkyl benzenesulfonamide: A single-step synthesis from benzenesulfonamide via hemiaminal" @default.
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- W2150460698 doi "https://doi.org/10.1016/j.ejmech.2006.09.021" @default.
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