Matches in SemOpenAlex for { <https://semopenalex.org/work/W2150463741> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2150463741 endingPage "921" @default.
- W2150463741 startingPage "918" @default.
- W2150463741 abstract "Escherichia coli serotype O157:H7 do not exhibit beta-glucuronidase (GUD) activity but carry the gusA gene (uidA) that encodes for GUD. In trans-complementation, the gusA gene cloned from the GUD-positive variant strain 493-89 effectively restored GUD activity in O157:H7 strain 35150. Comparison of gusA sequences from the GUD-negative 35150 strain to that of 493-89 revealed several base mutations, including a guanosine (G) dinucleotide insertion that caused a frameshift in the 35150 gusA gene and introduced a predicted premature termination codon. This explains the absence of GUD activity in O157:H7. A 35150 gusA construct from which the G-G insertion was deleted restored activity in GUD-negative O157:H7 transformants. The G-G insertion was present in all GUD-negative O157:H7 strains but was absent in their GUD-positive variants. The G-G insertion that produced the characteristic GUD-negative phenotype to O157:H7 strains appeared later than the other gusA mutations in the evolutionary emergence of O157:H7." @default.
- W2150463741 created "2016-06-24" @default.
- W2150463741 creator A5013813214 @default.
- W2150463741 creator A5014703566 @default.
- W2150463741 creator A5074430162 @default.
- W2150463741 date "2001-10-01" @default.
- W2150463741 modified "2023-09-24" @default.
- W2150463741 title "Genetic and Evolutionary Analysis of Mutations in the<i>gusA</i>Gene That Cause the Absence of β‐Glucuronidase Activity in<i>Escherichia coli</i>O157:H7" @default.
- W2150463741 cites W1525234204 @default.
- W2150463741 cites W1709361490 @default.
- W2150463741 cites W1766948196 @default.
- W2150463741 cites W1860937064 @default.
- W2150463741 cites W1887783758 @default.
- W2150463741 cites W1978862919 @default.
- W2150463741 cites W1997673845 @default.
- W2150463741 cites W2036656010 @default.
- W2150463741 cites W2053084680 @default.
- W2150463741 cites W2054908542 @default.
- W2150463741 cites W2106665403 @default.
- W2150463741 cites W2140677653 @default.
- W2150463741 cites W2144634347 @default.
- W2150463741 cites W2146316771 @default.
- W2150463741 cites W2160910028 @default.
- W2150463741 doi "https://doi.org/10.1086/323154" @default.
- W2150463741 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11510000" @default.
- W2150463741 hasPublicationYear "2001" @default.
- W2150463741 type Work @default.
- W2150463741 sameAs 2150463741 @default.
- W2150463741 citedByCount "59" @default.
- W2150463741 countsByYear W21504637412012 @default.
- W2150463741 countsByYear W21504637412013 @default.
- W2150463741 countsByYear W21504637412014 @default.
- W2150463741 countsByYear W21504637412015 @default.
- W2150463741 countsByYear W21504637412017 @default.
- W2150463741 countsByYear W21504637412018 @default.
- W2150463741 countsByYear W21504637412019 @default.
- W2150463741 countsByYear W21504637412020 @default.
- W2150463741 countsByYear W21504637412022 @default.
- W2150463741 crossrefType "journal-article" @default.
- W2150463741 hasAuthorship W2150463741A5013813214 @default.
- W2150463741 hasAuthorship W2150463741A5014703566 @default.
- W2150463741 hasAuthorship W2150463741A5074430162 @default.
- W2150463741 hasBestOaLocation W21504637411 @default.
- W2150463741 hasConcept C104317684 @default.
- W2150463741 hasConcept C105702510 @default.
- W2150463741 hasConcept C127716648 @default.
- W2150463741 hasConcept C188082640 @default.
- W2150463741 hasConcept C20580545 @default.
- W2150463741 hasConcept C2778022156 @default.
- W2150463741 hasConcept C29906990 @default.
- W2150463741 hasConcept C501734568 @default.
- W2150463741 hasConcept C54355233 @default.
- W2150463741 hasConcept C547475151 @default.
- W2150463741 hasConcept C86803240 @default.
- W2150463741 hasConcept C89423630 @default.
- W2150463741 hasConceptScore W2150463741C104317684 @default.
- W2150463741 hasConceptScore W2150463741C105702510 @default.
- W2150463741 hasConceptScore W2150463741C127716648 @default.
- W2150463741 hasConceptScore W2150463741C188082640 @default.
- W2150463741 hasConceptScore W2150463741C20580545 @default.
- W2150463741 hasConceptScore W2150463741C2778022156 @default.
- W2150463741 hasConceptScore W2150463741C29906990 @default.
- W2150463741 hasConceptScore W2150463741C501734568 @default.
- W2150463741 hasConceptScore W2150463741C54355233 @default.
- W2150463741 hasConceptScore W2150463741C547475151 @default.
- W2150463741 hasConceptScore W2150463741C86803240 @default.
- W2150463741 hasConceptScore W2150463741C89423630 @default.
- W2150463741 hasIssue "7" @default.
- W2150463741 hasLocation W21504637411 @default.
- W2150463741 hasLocation W21504637412 @default.
- W2150463741 hasOpenAccess W2150463741 @default.
- W2150463741 hasPrimaryLocation W21504637411 @default.
- W2150463741 hasRelatedWork W1581651310 @default.
- W2150463741 hasRelatedWork W1979176079 @default.
- W2150463741 hasRelatedWork W2009647017 @default.
- W2150463741 hasRelatedWork W2048347320 @default.
- W2150463741 hasRelatedWork W2049046197 @default.
- W2150463741 hasRelatedWork W2084926656 @default.
- W2150463741 hasRelatedWork W2098533677 @default.
- W2150463741 hasRelatedWork W2121760608 @default.
- W2150463741 hasRelatedWork W2128902294 @default.
- W2150463741 hasRelatedWork W59781516 @default.
- W2150463741 hasVolume "184" @default.
- W2150463741 isParatext "false" @default.
- W2150463741 isRetracted "false" @default.
- W2150463741 magId "2150463741" @default.
- W2150463741 workType "article" @default.