Matches in SemOpenAlex for { <https://semopenalex.org/work/W2150489343> ?p ?o ?g. }
- W2150489343 endingPage "6140" @default.
- W2150489343 startingPage "6132" @default.
- W2150489343 abstract "ABSTRACT A major Salmonella component involved in cellular activation is the lipopolysaccharide (LPS) molecule which can act as a dendritic cell (DC) stimulator. The structure of the lipid A domain of the LPS molecule dictates its immunostimulatory capacity with various cell types. In this study, the role of lipid A as an integral component of Salmonella in stimulating murine DCs was studied by using a Salmonella enterica serovar Typhimurium lpxM mutant with defective lipid A. This study revealed that a mutation in lpxM did not significantly affect the ability of bacteria to activate DCs. Although the lpxM mutant less tumor necrosis factor alpha, interleukin-1β, and inducible nitric oxide synthase than the parental strain, this was only seen at lower multiplicities of infection (MOIs). Both strains upregulated surface molecule expression on DCs and augmented the T-cell-stimulating capacity of these cells in an MOI-independent manner. Thus, the lpxM mutation did not appear to affect the stimulatory capacity of the Salmonella mutant." @default.
- W2150489343 created "2016-06-24" @default.
- W2150489343 creator A5045650550 @default.
- W2150489343 creator A5059622534 @default.
- W2150489343 creator A5063395363 @default.
- W2150489343 creator A5070935391 @default.
- W2150489343 date "2003-11-01" @default.
- W2150489343 modified "2023-09-26" @default.
- W2150489343 title "<i>Salmonella enterica</i> Serovar Typhimurium Expressing Mutant Lipid A with Decreased Endotoxicity Causes Maturation of Murine Dendritic Cells" @default.
- W2150489343 cites W148337095 @default.
- W2150489343 cites W1595241211 @default.
- W2150489343 cites W1612465238 @default.
- W2150489343 cites W1804793662 @default.
- W2150489343 cites W1903954089 @default.
- W2150489343 cites W1922098314 @default.
- W2150489343 cites W1967501462 @default.
- W2150489343 cites W1968789591 @default.
- W2150489343 cites W1976907957 @default.
- W2150489343 cites W1981124978 @default.
- W2150489343 cites W1985782125 @default.
- W2150489343 cites W1990802251 @default.
- W2150489343 cites W1997257161 @default.
- W2150489343 cites W2006697711 @default.
- W2150489343 cites W2007107629 @default.
- W2150489343 cites W2008077535 @default.
- W2150489343 cites W2011403272 @default.
- W2150489343 cites W2020483175 @default.
- W2150489343 cites W2042048278 @default.
- W2150489343 cites W2050828970 @default.
- W2150489343 cites W2052481832 @default.
- W2150489343 cites W2054019820 @default.
- W2150489343 cites W2067683067 @default.
- W2150489343 cites W2074528554 @default.
- W2150489343 cites W2080381322 @default.
- W2150489343 cites W2085198912 @default.
- W2150489343 cites W2092128665 @default.
- W2150489343 cites W2094373273 @default.
- W2150489343 cites W2100837269 @default.
- W2150489343 cites W2100851332 @default.
- W2150489343 cites W2111220263 @default.
- W2150489343 cites W2111695773 @default.
- W2150489343 cites W2112643590 @default.
- W2150489343 cites W2115205513 @default.
- W2150489343 cites W2117770420 @default.
- W2150489343 cites W2120046045 @default.
- W2150489343 cites W2120227455 @default.
- W2150489343 cites W2124707045 @default.
- W2150489343 cites W2130322182 @default.
- W2150489343 cites W2130673227 @default.
- W2150489343 cites W2131383434 @default.
- W2150489343 cites W2136793561 @default.
- W2150489343 cites W2139202421 @default.
- W2150489343 cites W2139620037 @default.
- W2150489343 cites W2141346620 @default.
- W2150489343 cites W2146867625 @default.
- W2150489343 cites W2155793921 @default.
- W2150489343 cites W2173272774 @default.
- W2150489343 cites W4242852378 @default.
- W2150489343 cites W4293048996 @default.
- W2150489343 doi "https://doi.org/10.1128/iai.71.11.6132-6140.2003" @default.
- W2150489343 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/219569" @default.
- W2150489343 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14573628" @default.
- W2150489343 hasPublicationYear "2003" @default.
- W2150489343 type Work @default.
- W2150489343 sameAs 2150489343 @default.
- W2150489343 citedByCount "17" @default.
- W2150489343 countsByYear W21504893432012 @default.
- W2150489343 countsByYear W21504893432013 @default.
- W2150489343 countsByYear W21504893432014 @default.
- W2150489343 countsByYear W21504893432016 @default.
- W2150489343 crossrefType "journal-article" @default.
- W2150489343 hasAuthorship W2150489343A5045650550 @default.
- W2150489343 hasAuthorship W2150489343A5059622534 @default.
- W2150489343 hasAuthorship W2150489343A5063395363 @default.
- W2150489343 hasAuthorship W2150489343A5070935391 @default.
- W2150489343 hasBestOaLocation W21504893432 @default.
- W2150489343 hasConcept C104317684 @default.
- W2150489343 hasConcept C143065580 @default.
- W2150489343 hasConcept C144464004 @default.
- W2150489343 hasConcept C17991360 @default.
- W2150489343 hasConcept C203014093 @default.
- W2150489343 hasConcept C2778170410 @default.
- W2150489343 hasConcept C2778754761 @default.
- W2150489343 hasConcept C2779607309 @default.
- W2150489343 hasConcept C2781065037 @default.
- W2150489343 hasConcept C523546767 @default.
- W2150489343 hasConcept C54355233 @default.
- W2150489343 hasConcept C55493867 @default.
- W2150489343 hasConcept C86803240 @default.
- W2150489343 hasConcept C8891405 @default.
- W2150489343 hasConcept C89423630 @default.
- W2150489343 hasConcept C95444343 @default.
- W2150489343 hasConceptScore W2150489343C104317684 @default.
- W2150489343 hasConceptScore W2150489343C143065580 @default.
- W2150489343 hasConceptScore W2150489343C144464004 @default.
- W2150489343 hasConceptScore W2150489343C17991360 @default.
- W2150489343 hasConceptScore W2150489343C203014093 @default.
- W2150489343 hasConceptScore W2150489343C2778170410 @default.