Matches in SemOpenAlex for { <https://semopenalex.org/work/W2150554911> ?p ?o ?g. }
- W2150554911 endingPage "4722" @default.
- W2150554911 startingPage "4713" @default.
- W2150554911 abstract "An integrated smart microfluidic device consisting of nickel micropillars, microvalves, and microchannels was developed for specific capture and sorting of cells. A regular hexagonal array of nickel micropillars was integrated on the bottom of a microchannel by standard photolithography, which can generate strong induced magnetic field gradients under an external magnetic field to efficiently trap superparamagnetic beads (SPMBs) in a flowing stream, forming a bed with sufficient magnetic beads as a capture zone. Fluids could be manipulated by programmed controlling the integrated air-pressure-actuated microvalves, based on which in situ bio-functionalization of SPMBs trapped in the capture zone was realized by covalent attachment of specific proteins directly to their surface on the integrated microfluidic device. In this case, only small volumes of protein solutions (62.5 nL in the capture zone; 375 nL in total volume needed to fill the device from inlet A to the intersection of outlet channels F and G) can meet the need for protein! The newly designed microfluidic device reduced greatly chemical and biological reagent consumption and simplified drastically tedious manual handling. Based on the specific interaction between wheat germ agglutinin (WGA) and N-acetylglucosamine on the cell membrane, A549 cancer cells were effectively captured and sorted on the microfluidic device. Capture efficiency ranged from 62 to 74%. The integrated microfluidic device provides a reliable technique for cell sorting." @default.
- W2150554911 created "2016-06-24" @default.
- W2150554911 creator A5018465248 @default.
- W2150554911 creator A5051736674 @default.
- W2150554911 creator A5059573202 @default.
- W2150554911 creator A5059754075 @default.
- W2150554911 creator A5075193593 @default.
- W2150554911 creator A5085462851 @default.
- W2150554911 creator A5088239865 @default.
- W2150554911 creator A5088665887 @default.
- W2150554911 date "2007-12-01" @default.
- W2150554911 modified "2023-10-09" @default.
- W2150554911 title "A micropillar‐integrated smart microfluidic device for specific capture and sorting of cells" @default.
- W2150554911 cites W1560194095 @default.
- W2150554911 cites W1967590589 @default.
- W2150554911 cites W1972466773 @default.
- W2150554911 cites W1975687263 @default.
- W2150554911 cites W1977077195 @default.
- W2150554911 cites W1982293678 @default.
- W2150554911 cites W1983886583 @default.
- W2150554911 cites W1988327316 @default.
- W2150554911 cites W1992400700 @default.
- W2150554911 cites W1995770358 @default.
- W2150554911 cites W1997313982 @default.
- W2150554911 cites W1999231401 @default.
- W2150554911 cites W2008891347 @default.
- W2150554911 cites W2013117405 @default.
- W2150554911 cites W2013992558 @default.
- W2150554911 cites W2038908517 @default.
- W2150554911 cites W2050658916 @default.
- W2150554911 cites W2051976574 @default.
- W2150554911 cites W2070047785 @default.
- W2150554911 cites W2071311642 @default.
- W2150554911 cites W2084315077 @default.
- W2150554911 cites W2087175688 @default.
- W2150554911 cites W2090983970 @default.
- W2150554911 cites W2091718555 @default.
- W2150554911 cites W2108012118 @default.
- W2150554911 cites W2116208923 @default.
- W2150554911 cites W2126354472 @default.
- W2150554911 cites W2132066511 @default.
- W2150554911 cites W2140219590 @default.
- W2150554911 cites W2151704374 @default.
- W2150554911 cites W2152238532 @default.
- W2150554911 cites W2160035051 @default.
- W2150554911 cites W2167294135 @default.
- W2150554911 cites W2461703751 @default.
- W2150554911 cites W3007599434 @default.
- W2150554911 doi "https://doi.org/10.1002/elps.200700212" @default.
- W2150554911 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18008303" @default.
- W2150554911 hasPublicationYear "2007" @default.
- W2150554911 type Work @default.
- W2150554911 sameAs 2150554911 @default.
- W2150554911 citedByCount "76" @default.
- W2150554911 countsByYear W21505549112012 @default.
- W2150554911 countsByYear W21505549112013 @default.
- W2150554911 countsByYear W21505549112014 @default.
- W2150554911 countsByYear W21505549112015 @default.
- W2150554911 countsByYear W21505549112016 @default.
- W2150554911 countsByYear W21505549112017 @default.
- W2150554911 countsByYear W21505549112018 @default.
- W2150554911 countsByYear W21505549112019 @default.
- W2150554911 countsByYear W21505549112020 @default.
- W2150554911 countsByYear W21505549112021 @default.
- W2150554911 countsByYear W21505549112022 @default.
- W2150554911 countsByYear W21505549112023 @default.
- W2150554911 crossrefType "journal-article" @default.
- W2150554911 hasAuthorship W2150554911A5018465248 @default.
- W2150554911 hasAuthorship W2150554911A5051736674 @default.
- W2150554911 hasAuthorship W2150554911A5059573202 @default.
- W2150554911 hasAuthorship W2150554911A5059754075 @default.
- W2150554911 hasAuthorship W2150554911A5075193593 @default.
- W2150554911 hasAuthorship W2150554911A5085462851 @default.
- W2150554911 hasAuthorship W2150554911A5088239865 @default.
- W2150554911 hasAuthorship W2150554911A5088665887 @default.
- W2150554911 hasConcept C105487726 @default.
- W2150554911 hasConcept C111696304 @default.
- W2150554911 hasConcept C115260700 @default.
- W2150554911 hasConcept C121332964 @default.
- W2150554911 hasConcept C171250308 @default.
- W2150554911 hasConcept C192562407 @default.
- W2150554911 hasConcept C199360897 @default.
- W2150554911 hasConcept C23792430 @default.
- W2150554911 hasConcept C32546565 @default.
- W2150554911 hasConcept C41008148 @default.
- W2150554911 hasConcept C62520636 @default.
- W2150554911 hasConcept C63662833 @default.
- W2150554911 hasConcept C8673954 @default.
- W2150554911 hasConceptScore W2150554911C105487726 @default.
- W2150554911 hasConceptScore W2150554911C111696304 @default.
- W2150554911 hasConceptScore W2150554911C115260700 @default.
- W2150554911 hasConceptScore W2150554911C121332964 @default.
- W2150554911 hasConceptScore W2150554911C171250308 @default.
- W2150554911 hasConceptScore W2150554911C192562407 @default.
- W2150554911 hasConceptScore W2150554911C199360897 @default.
- W2150554911 hasConceptScore W2150554911C23792430 @default.
- W2150554911 hasConceptScore W2150554911C32546565 @default.
- W2150554911 hasConceptScore W2150554911C41008148 @default.