Matches in SemOpenAlex for { <https://semopenalex.org/work/W2150579891> ?p ?o ?g. }
- W2150579891 abstract "Viral hepatitis is a major health problem worldwide, the principal cause of cirrhosis and hepatocarcinoma. Once cirrhosis occurs, the consequences of liver dysfunction and portal hypertension become evident and, sometimes, life threatening for patients. Among the various complications of liver cirrhosis, the alteration of haemostatic balance is often a hard challenge for the clinician, since it is capable to predispose both to bleeding or thrombosis. In this review, we analyze the principal aspects of procoagulant, anticoagulant and fibrinolytic capacity of cirrhotic patients, which appears to be variably altered in all these aspects, not only in the direction of a tendency to bleeding. Laboratory investigations, at present, may provide only a partial representation of this condition, because of the impossibility to obtain a test capable to furnish a global overview of the haemostatic system and to reproduce in vivo conditions. Furthermore, we describe the pathophysiological mechanisms underlying bleeding manifestations and thrombosis development in cirrhotic patients, which should be considered not only as obvious consequences of the advanced liver disease but, rather, as the result of a complex interaction between inherited and acquired factors." @default.
- W2150579891 created "2016-06-24" @default.
- W2150579891 creator A5054304877 @default.
- W2150579891 creator A5063416087 @default.
- W2150579891 creator A5078126497 @default.
- W2150579891 date "2009-01-01" @default.
- W2150579891 modified "2023-09-25" @default.
- W2150579891 title "VIRAL CIRRHOSIS: AN OVERVIEW OF HAEMOSTATIC ALTERATIONS AND CLINICAL CONSEQUENCES" @default.
- W2150579891 cites W123098684 @default.
- W2150579891 cites W12569229 @default.
- W2150579891 cites W1490907837 @default.
- W2150579891 cites W1549228081 @default.
- W2150579891 cites W1551808514 @default.
- W2150579891 cites W1560253646 @default.
- W2150579891 cites W163257244 @default.
- W2150579891 cites W1753709933 @default.
- W2150579891 cites W1775295856 @default.
- W2150579891 cites W1777106014 @default.
- W2150579891 cites W1819215251 @default.
- W2150579891 cites W1848837409 @default.
- W2150579891 cites W1908398222 @default.
- W2150579891 cites W191436139 @default.
- W2150579891 cites W1963531850 @default.
- W2150579891 cites W1966856947 @default.
- W2150579891 cites W1968641413 @default.
- W2150579891 cites W1969138919 @default.
- W2150579891 cites W1970145746 @default.
- W2150579891 cites W1972058538 @default.
- W2150579891 cites W1973815747 @default.
- W2150579891 cites W1974121285 @default.
- W2150579891 cites W1978794823 @default.
- W2150579891 cites W1979389409 @default.
- W2150579891 cites W1980568348 @default.
- W2150579891 cites W1985458557 @default.
- W2150579891 cites W1985483056 @default.
- W2150579891 cites W1985568976 @default.
- W2150579891 cites W1987187745 @default.
- W2150579891 cites W1989713925 @default.
- W2150579891 cites W1991019633 @default.
- W2150579891 cites W1991452357 @default.
- W2150579891 cites W1991843023 @default.
- W2150579891 cites W1993575120 @default.
- W2150579891 cites W1994134471 @default.
- W2150579891 cites W1994261447 @default.
- W2150579891 cites W1995876098 @default.
- W2150579891 cites W1997300998 @default.
- W2150579891 cites W1999364304 @default.
- W2150579891 cites W2000429990 @default.
- W2150579891 cites W2001563266 @default.
- W2150579891 cites W2001703132 @default.
- W2150579891 cites W2002248996 @default.
- W2150579891 cites W2004443172 @default.
- W2150579891 cites W2007083511 @default.
- W2150579891 cites W2014780671 @default.
- W2150579891 cites W2016572253 @default.
- W2150579891 cites W2016872608 @default.
- W2150579891 cites W2019075120 @default.
- W2150579891 cites W2019743060 @default.
- W2150579891 cites W2025478287 @default.
- W2150579891 cites W2025606754 @default.
- W2150579891 cites W2028213315 @default.
- W2150579891 cites W2032693555 @default.
- W2150579891 cites W2033097591 @default.
- W2150579891 cites W2033260776 @default.
- W2150579891 cites W2035150821 @default.
- W2150579891 cites W2041379274 @default.
- W2150579891 cites W2044341259 @default.
- W2150579891 cites W2045905507 @default.
- W2150579891 cites W2046466444 @default.
- W2150579891 cites W2048441761 @default.
- W2150579891 cites W2049145190 @default.
- W2150579891 cites W2050390293 @default.
- W2150579891 cites W2050653657 @default.
- W2150579891 cites W2054282727 @default.
- W2150579891 cites W2054641887 @default.
- W2150579891 cites W2057360098 @default.
- W2150579891 cites W2058671444 @default.
- W2150579891 cites W2059196197 @default.
- W2150579891 cites W2062811388 @default.
- W2150579891 cites W2063668704 @default.
- W2150579891 cites W2063957255 @default.
- W2150579891 cites W2064545046 @default.
- W2150579891 cites W2069915235 @default.
- W2150579891 cites W2072195523 @default.
- W2150579891 cites W2073015482 @default.
- W2150579891 cites W2074364154 @default.
- W2150579891 cites W2075601129 @default.
- W2150579891 cites W2076812615 @default.
- W2150579891 cites W2079103647 @default.
- W2150579891 cites W2079377965 @default.
- W2150579891 cites W2081162516 @default.
- W2150579891 cites W2087102978 @default.
- W2150579891 cites W2087226513 @default.
- W2150579891 cites W2087617682 @default.
- W2150579891 cites W2089571778 @default.
- W2150579891 cites W2091742879 @default.
- W2150579891 cites W2093904358 @default.
- W2150579891 cites W2103633994 @default.
- W2150579891 cites W2106109244 @default.
- W2150579891 cites W2115306556 @default.