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• W2150825798 endingPage "1483" @default.
• W2150825798 startingPage "1473" @default.
• W2150825798 abstract "Background: Prenatal alcohol exposure has been linked to deficits in processing speed in both infancy and later in childhood. This study was designed to examine prenatal alcohol-related deficits in both processing speed and processing efficiency in four domains of cognitive function. Methods: Black children (n= 337; age, 7.5 years), prospectively recruited to over-represent prenatal alcohol exposure at moderate-to-heavy levels, were assessed on four processing speed tasks, using a Sternberg paradigm. Hierarchical linear modeling was used to contrast overall processing speed, indicated by reaction time (RT) differences at the intercept, with processing efficiency, indicated by the slope of RT changes across increasing levels of task difficulty. Performance on these tasks within an effortful cognitive framework was compared with RT on a task involving relatively more automatic processing. Path analysis was used to examine the degree to which the effect of prenatal alcohol exposure on working memory was mediated by slower RT. Results: Prenatal alcohol exposure was associated with slower processing speed on several of the Sternberg tasks, and the number comparison task showed a specific deficit in processing efficiency. These effects on tasks involving effortful processing contrasted with the lack of performance differences on the more automatic RT measure. The relation of prenatal alcohol exposure to working memory was mediated, in part, by an associated reduction in processing speed. Conclusions: These data confirm reports by other investigators linking prenatal alcohol exposure to slower processing speed and show that this RT deficit is found within the context of complex cognition but not where automatic processing is involved. The reduction in RT accounts, in part, for the previously reported alcohol-related effects on working memory. The number comparison slope was the only specific component of information processing affected, confirming previous reports of a distinctive prenatal alcohol effect on number processing." @default.
• W2150825798 created "2016-06-24" @default.
• W2150825798 creator A5010069159 @default.
• W2150825798 creator A5026175668 @default.
• W2150825798 creator A5046362648 @default.
• W2150825798 date "2005-08-01" @default.
• W2150825798 modified "2023-09-30" @default.
• W2150825798 title "Relation of Prenatal Alcohol Exposure to Cognitive Processing Speed and Efficiency in Childhood" @default.
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• W2150825798 doi "https://doi.org/10.1097/01.alc.0000175036.34076.a0" @default.
• W2150825798 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16131856" @default.
• W2150825798 hasPublicationYear "2005" @default.
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