FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2150838769> ?p ?o ?g. }

• W2150838769 abstract "When a muscle is stretched while activated, its steady-state isometric force following stretch is greater than the corresponding purely isometric force. This so-called residual force enhancement (RFE) has been observed for half a century, yet its mechanism remains unknown. Recent experiments suggest that RFE is not caused by non-uniformities in sarcomere lengths, as had been assumed for a long time, and cannot be explained primarily with increases in passive force, but is directly related to the kinetics of the cross-bridge cycle. Specifically, it has been suggested that stretching an attached cross-bridge increases its dwell time and duty ratio; therefore, the proportion of attached cross-bridges in a muscle would be increased by stretch, thereby causing RFE. A three bead laser trap setup was used for testing single cross-bridge (myosin II) interactions with actin. Upon attachment of a cross-bridge, a stretch or shortening of the cross-bridge was applied with a force of about 1.0 pN. The hypothesis that stretching a single cross-bridge increases its dwell time and duty ratio was rejected. However, stretching caused an increase in the average steady-state force per cross-bridge (3.4+/-0.4 pN; n=433) compared to shortening (1.9+/-0.3 pN; n=689). Therefore, based on the results of this study, RFE cannot be explained by an increased duty ratio and the associated increase in proportion of attached cross-bridges, but might be associated with an increased force per cross-bridge." @default.
• W2150838769 created "2016-06-24" @default.
• W2150838769 creator A5069322953 @default.
• W2150838769 creator A5085963117 @default.
• W2150838769 date "2008-01-01" @default.
• W2150838769 modified "2023-10-16" @default.
• W2150838769 title "Cross-bridge induced force enhancement?" @default.
• W2150838769 cites W108449833 @default.
• W2150838769 cites W1519451866 @default.
• W2150838769 cites W1522497566 @default.
• W2150838769 cites W1978243335 @default.
• W2150838769 cites W1981068779 @default.
• W2150838769 cites W1983572701 @default.
• W2150838769 cites W1995035844 @default.
• W2150838769 cites W2001758775 @default.
• W2150838769 cites W2009094078 @default.
• W2150838769 cites W2020998038 @default.
• W2150838769 cites W2022558995 @default.
• W2150838769 cites W2037638005 @default.
• W2150838769 cites W2044629144 @default.
• W2150838769 cites W2053173762 @default.
• W2150838769 cites W2059158601 @default.
• W2150838769 cites W2073965063 @default.
• W2150838769 cites W2074969278 @default.
• W2150838769 cites W2095554109 @default.
• W2150838769 cites W2099666369 @default.
• W2150838769 cites W2100561868 @default.
• W2150838769 cites W2118855111 @default.
• W2150838769 cites W2136933934 @default.
• W2150838769 cites W2142850492 @default.
• W2150838769 cites W2144575888 @default.
• W2150838769 cites W2145360268 @default.
• W2150838769 cites W2151274733 @default.
• W2150838769 cites W2165183210 @default.
• W2150838769 doi "https://doi.org/10.1016/j.jbiomech.2008.02.010" @default.
• W2150838769 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18387614" @default.
• W2150838769 hasPublicationYear "2008" @default.
• W2150838769 type Work @default.
• W2150838769 sameAs 2150838769 @default.
• W2150838769 citedByCount "26" @default.
• W2150838769 countsByYear W21508387692012 @default.
• W2150838769 countsByYear W21508387692013 @default.
• W2150838769 countsByYear W21508387692014 @default.
• W2150838769 countsByYear W21508387692015 @default.
• W2150838769 countsByYear W21508387692016 @default.
• W2150838769 countsByYear W21508387692017 @default.
• W2150838769 countsByYear W21508387692018 @default.
• W2150838769 countsByYear W21508387692020 @default.
• W2150838769 countsByYear W21508387692023 @default.
• W2150838769 crossrefType "journal-article" @default.
• W2150838769 hasAuthorship W2150838769A5069322953 @default.
• W2150838769 hasAuthorship W2150838769A5085963117 @default.
• W2150838769 hasConcept C100776233 @default.
• W2150838769 hasConcept C103486182 @default.
• W2150838769 hasConcept C105702510 @default.
• W2150838769 hasConcept C121332964 @default.
• W2150838769 hasConcept C127413603 @default.
• W2150838769 hasConcept C134018914 @default.
• W2150838769 hasConcept C163258240 @default.
• W2150838769 hasConcept C185592680 @default.
• W2150838769 hasConcept C192562407 @default.
• W2150838769 hasConcept C19527891 @default.
• W2150838769 hasConcept C199822604 @default.
• W2150838769 hasConcept C207200792 @default.
• W2150838769 hasConcept C2993792317 @default.
• W2150838769 hasConcept C42407357 @default.
• W2150838769 hasConcept C55493867 @default.
• W2150838769 hasConcept C57879066 @default.
• W2150838769 hasConcept C66938386 @default.
• W2150838769 hasConcept C68731436 @default.
• W2150838769 hasConcept C6997183 @default.
• W2150838769 hasConcept C86803240 @default.
• W2150838769 hasConcept C97355855 @default.
• W2150838769 hasConceptScore W2150838769C100776233 @default.
• W2150838769 hasConceptScore W2150838769C103486182 @default.
• W2150838769 hasConceptScore W2150838769C105702510 @default.
• W2150838769 hasConceptScore W2150838769C121332964 @default.
• W2150838769 hasConceptScore W2150838769C127413603 @default.
• W2150838769 hasConceptScore W2150838769C134018914 @default.
• W2150838769 hasConceptScore W2150838769C163258240 @default.
• W2150838769 hasConceptScore W2150838769C185592680 @default.
• W2150838769 hasConceptScore W2150838769C192562407 @default.
• W2150838769 hasConceptScore W2150838769C19527891 @default.
• W2150838769 hasConceptScore W2150838769C199822604 @default.
• W2150838769 hasConceptScore W2150838769C207200792 @default.
• W2150838769 hasConceptScore W2150838769C2993792317 @default.
• W2150838769 hasConceptScore W2150838769C42407357 @default.
• W2150838769 hasConceptScore W2150838769C55493867 @default.
• W2150838769 hasConceptScore W2150838769C57879066 @default.
• W2150838769 hasConceptScore W2150838769C66938386 @default.
• W2150838769 hasConceptScore W2150838769C68731436 @default.
• W2150838769 hasConceptScore W2150838769C6997183 @default.
• W2150838769 hasConceptScore W2150838769C86803240 @default.
• W2150838769 hasConceptScore W2150838769C97355855 @default.
• W2150838769 hasLocation W21508387691 @default.
• W2150838769 hasLocation W21508387692 @default.
• W2150838769 hasOpenAccess W2150838769 @default.
• W2150838769 hasPrimaryLocation W21508387691 @default.
• W2150838769 hasRelatedWork W1569045116 @default.
• W2150838769 hasRelatedWork W1573366176 @default.

• next