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• W2150860306 abstract "Functional mobility and cognitive function often decline with age. We previously found that functional mobility as measured by the Timed Up and Go Test (TUG) was associated with cognitive performance for visually-encoded (i.e., for location and face) working memory (WM) in older adults. This suggests a common neural basis between TUG and visual WM. To elucidate this relationship further, the present study aimed to examine the neural basis for the WM-mobility association. In accordance with the well-known neural compensation model in aging, we hypothesized that attentional brain activation for easy WM would increase in participants with lower mobility. The data from 32 healthy older adults were analyzed, including brain activation during easy WM tasks via functional Magnetic Resonance Imaging (fMRI) and mobility performance via both TUG and a simple walking test. WM performance was significantly correlated with TUG but not with simple walking. Some prefrontal brain activations during WM were negatively correlated with TUG performance, while positive correlations were found in subcortical structures including the thalamus, putamen and cerebellum. Moreover, activation of the subcortical regions was significantly correlated with WM performance, with less activation for lower WM performers. These results indicate that older adults with lower mobility used more cortical (frontal) and fewer subcortical resources for easy WM tasks. To date, the frontal compensation has been proposed separately in the motor and cognitive domains, which have been assumed to compensate for dysfunction of the other brain areas; however, such dysfunction was less clear in previous studies. The present study observed such dysfunction as degraded activation associated with lower performance, which was found in the subcortical regions. We conclude that a common dysfunction-compensation activation pattern is likely the neural basis for the association between visual WM and functional mobility." @default.
• W2150860306 created "2016-06-24" @default.
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• W2150860306 date "2015-09-29" @default.
• W2150860306 modified "2023-10-18" @default.
• W2150860306 title "Brain activation during visual working memory correlates with behavioral mobility performance in older adults" @default.
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• W2150860306 cites W1965086680 @default.
• W2150860306 cites W1967333153 @default.
• W2150860306 cites W1971281741 @default.
• W2150860306 cites W1972201572 @default.
• W2150860306 cites W1974704788 @default.
• W2150860306 cites W1997538961 @default.
• W2150860306 cites W1999717910 @default.
• W2150860306 cites W2000265708 @default.
• W2150860306 cites W2000697043 @default.
• W2150860306 cites W2004413063 @default.
• W2150860306 cites W2008854521 @default.
• W2150860306 cites W2010285555 @default.
• W2150860306 cites W2012514074 @default.
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• W2150860306 cites W2018481012 @default.
• W2150860306 cites W2023051498 @default.
• W2150860306 cites W2026776183 @default.
• W2150860306 cites W2031170958 @default.
• W2150860306 cites W2037682089 @default.
• W2150860306 cites W2047416352 @default.
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• W2150860306 cites W2061195971 @default.
• W2150860306 cites W2061874720 @default.
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• W2150860306 cites W2081030913 @default.
• W2150860306 cites W2089725106 @default.
• W2150860306 cites W2096707172 @default.
• W2150860306 cites W2097145605 @default.
• W2150860306 cites W2097263602 @default.
• W2150860306 cites W2097830253 @default.
• W2150860306 cites W2098508288 @default.
• W2150860306 cites W2100011555 @default.
• W2150860306 cites W2107501599 @default.
• W2150860306 cites W2110533829 @default.
• W2150860306 cites W2113622185 @default.
• W2150860306 cites W2116516133 @default.
• W2150860306 cites W2117800611 @default.
• W2150860306 cites W2118560750 @default.
• W2150860306 cites W2120448275 @default.
• W2150860306 cites W2121948211 @default.
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• W2150860306 cites W2124517301 @default.
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• W2150860306 doi "https://doi.org/10.3389/fnagi.2015.00186" @default.
• W2150860306 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4586278" @default.
• W2150860306 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26483683" @default.
• W2150860306 hasPublicationYear "2015" @default.
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