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- W2150866787 abstract "Functional gastrointestinal disorders (FGID) affect 15%-20% of the general pediatric and adult population. Animal models suggest that a neonatal stress such as invasive procedures and maternal separation could be responsible for visceral hypersensitivity and FGID. We tested the hypothesis that congenital esophageal atresia (EA), a condition corrected during the neonatal period and associated with multiple stresses, is a clinically significant risk factor for the development of FGID later in life. We postulated that, to be clinically significant, the effect of neonatal stress on the incidence of FGID should be as strong as that of enteric infections in the development of irritable bowel syndrome in children." @default.
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- W2150866787 date "2012-10-31" @default.
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- W2150866787 title "Functional Gastrointestinal Disorders Induced by Esophageal Atresia Surgery: Is It Valid in Humans?" @default.
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- W2150866787 doi "https://doi.org/10.5056/jnm.2012.18.4.406" @default.
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