Matches in SemOpenAlex for { <https://semopenalex.org/work/W2150919799> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2150919799 abstract "Simple, specific, economical and precise high performance liquid chromatographic method for the simultaneous determination of ezetimibe and Atorvastatin in API (active pharmaceutical ingredient) and formulation has been developed and validated. Chromatography was carried out at 30°C on a prepacked Zorbax SB C18 (5 mm, 250×4.6 mm) column with the 0.02 M Potassium dihydrogen phosphate: Acetonitrile: Methanol (10:40:50, v/v/v) was used as the mobile phase. The UV detection was carried at 236 nm. The results obtained showed good agreement with the declared contents. Ezetimibe and Atorvastatin separated in less than 10 min with good resolution and minimal tailing and without interference of excipients. The retention times of ezetimibe and Atorvastatin were 5.7 min and 9.1 min, respectively. The method was linear in the range of 5–50 μg/ml for Ezetimibe concentration with a correlationco-efficient 0.9992 and in the range 5–60 μg/ml for Atorvastatin concentrations having correlation co-efficient 0.9994 and the recovery was 99-102%. The method was validated according to ICH guidelines and the acceptance criteria for accuracy, precision, linearity, specificity and system suitability were met in all cases. The proposed method can be used for quantitative determination of Ezetimibe and Atorvastatin combination from API and formulations." @default.
- W2150919799 created "2016-06-24" @default.
- W2150919799 creator A5011534811 @default.
- W2150919799 creator A5039288776 @default.
- W2150919799 creator A5043481768 @default.
- W2150919799 date "2012-01-01" @default.
- W2150919799 modified "2023-09-26" @default.
- W2150919799 title "Stability Indicating Method Development for Simultaneous Estimation of Ezetimibe and Atorvastatin in Pharmaceutical Formulations by RP-HPLC" @default.
- W2150919799 cites W1576092319 @default.
- W2150919799 cites W1970475651 @default.
- W2150919799 cites W1992084132 @default.
- W2150919799 cites W1992985052 @default.
- W2150919799 cites W2023183409 @default.
- W2150919799 cites W2024111413 @default.
- W2150919799 cites W2024644426 @default.
- W2150919799 cites W2033674890 @default.
- W2150919799 cites W2034961413 @default.
- W2150919799 cites W2091218405 @default.
- W2150919799 cites W2138673524 @default.
- W2150919799 cites W2160518175 @default.
- W2150919799 cites W2170460248 @default.
- W2150919799 cites W2521418001 @default.
- W2150919799 cites W77798198 @default.
- W2150919799 doi "https://doi.org/10.4172/2153-2435.1000164" @default.
- W2150919799 hasPublicationYear "2012" @default.
- W2150919799 type Work @default.
- W2150919799 sameAs 2150919799 @default.
- W2150919799 citedByCount "11" @default.
- W2150919799 countsByYear W21509197992013 @default.
- W2150919799 countsByYear W21509197992014 @default.
- W2150919799 countsByYear W21509197992015 @default.
- W2150919799 countsByYear W21509197992016 @default.
- W2150919799 countsByYear W21509197992017 @default.
- W2150919799 crossrefType "journal-article" @default.
- W2150919799 hasAuthorship W2150919799A5011534811 @default.
- W2150919799 hasAuthorship W2150919799A5039288776 @default.
- W2150919799 hasAuthorship W2150919799A5043481768 @default.
- W2150919799 hasConcept C138268822 @default.
- W2150919799 hasConcept C154945302 @default.
- W2150919799 hasConcept C178790620 @default.
- W2150919799 hasConcept C179998833 @default.
- W2150919799 hasConcept C185592680 @default.
- W2150919799 hasConcept C2776839432 @default.
- W2150919799 hasConcept C2777482532 @default.
- W2150919799 hasConcept C2778657065 @default.
- W2150919799 hasConcept C2779607525 @default.
- W2150919799 hasConcept C41008148 @default.
- W2150919799 hasConcept C43617362 @default.
- W2150919799 hasConcept C45904493 @default.
- W2150919799 hasConcept C55493867 @default.
- W2150919799 hasConcept C71924100 @default.
- W2150919799 hasConcept C77281830 @default.
- W2150919799 hasConcept C96616956 @default.
- W2150919799 hasConcept C98274493 @default.
- W2150919799 hasConceptScore W2150919799C138268822 @default.
- W2150919799 hasConceptScore W2150919799C154945302 @default.
- W2150919799 hasConceptScore W2150919799C178790620 @default.
- W2150919799 hasConceptScore W2150919799C179998833 @default.
- W2150919799 hasConceptScore W2150919799C185592680 @default.
- W2150919799 hasConceptScore W2150919799C2776839432 @default.
- W2150919799 hasConceptScore W2150919799C2777482532 @default.
- W2150919799 hasConceptScore W2150919799C2778657065 @default.
- W2150919799 hasConceptScore W2150919799C2779607525 @default.
- W2150919799 hasConceptScore W2150919799C41008148 @default.
- W2150919799 hasConceptScore W2150919799C43617362 @default.
- W2150919799 hasConceptScore W2150919799C45904493 @default.
- W2150919799 hasConceptScore W2150919799C55493867 @default.
- W2150919799 hasConceptScore W2150919799C71924100 @default.
- W2150919799 hasConceptScore W2150919799C77281830 @default.
- W2150919799 hasConceptScore W2150919799C96616956 @default.
- W2150919799 hasConceptScore W2150919799C98274493 @default.
- W2150919799 hasIssue "06" @default.
- W2150919799 hasLocation W21509197991 @default.
- W2150919799 hasOpenAccess W2150919799 @default.
- W2150919799 hasPrimaryLocation W21509197991 @default.
- W2150919799 hasRelatedWork W1587971292 @default.
- W2150919799 hasRelatedWork W1934434878 @default.
- W2150919799 hasRelatedWork W1970590437 @default.
- W2150919799 hasRelatedWork W2029713923 @default.
- W2150919799 hasRelatedWork W2041656680 @default.
- W2150919799 hasRelatedWork W2100326325 @default.
- W2150919799 hasRelatedWork W2103134123 @default.
- W2150919799 hasRelatedWork W2109989475 @default.
- W2150919799 hasRelatedWork W2156546172 @default.
- W2150919799 hasRelatedWork W2159395626 @default.
- W2150919799 hasRelatedWork W2185412032 @default.
- W2150919799 hasRelatedWork W2269774214 @default.
- W2150919799 hasRelatedWork W2272989766 @default.
- W2150919799 hasRelatedWork W2277098574 @default.
- W2150919799 hasRelatedWork W2572967866 @default.
- W2150919799 hasRelatedWork W2597554456 @default.
- W2150919799 hasRelatedWork W2604574021 @default.
- W2150919799 hasRelatedWork W1870373254 @default.
- W2150919799 hasRelatedWork W2100354074 @default.
- W2150919799 hasRelatedWork W2248114090 @default.
- W2150919799 hasVolume "03" @default.
- W2150919799 isParatext "false" @default.
- W2150919799 isRetracted "false" @default.
- W2150919799 magId "2150919799" @default.
- W2150919799 workType "article" @default.