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• W2151030992 abstract "Objective We evaluated the outcomes of patients undergoing major lower-extremity amputation who received packed red blood cell transfusion. Methods Using the dataset of the National Surgical Quality Improvement Program (2005–2011), we examined 5,739 above-knee and 6,725 below-knee amputations. Patients were stratified by perioperative (preoperative, intraoperative, or postoperative) blood transfusion. Outcomes included perioperative mortality, myocardial infarction (MI), thromboembolism, and duration of stay (DOS) at the hospital. Adjusted comparisons of outcomes between transfused and not-transfused patients were performed by matching the 2 groups for age, smoking, diabetes, renal failure, coronary artery disease, classification of the American Society of Anesthesiologists, functional status, and procedure type. Multivariable logistic and gamma regression were used to examine associations between transfusion and outcomes. Results Of the 12,464 amputations in the study cohort 2,133 (17%) required transfusion. The majority of the cases were performed for critical limb ischemia (8,205 amputations; 66%) and the overall 30-days mortality was 9%. In both crude and matched cohorts, although perioperative mortality and cardiac complication rates were similar, transfusion was associated with a greater incidence of pneumonia (crude: 6.1% vs 3%, P  Conclusion Among patients who had major lower-extremity amputation, perioperative transfusion independently predicted greater risks for perioperative pneumonia, thromboembolism, and prolonged hospital DOS." @default.
• W2151030992 created "2016-06-24" @default.
• W2151030992 creator A5000622050 @default.
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• W2151030992 date "2016-03-01" @default.
• W2151030992 modified "2023-09-24" @default.
• W2151030992 title "Reply: Blood transfusion is associated with increased risk of perioperative complications and prolonged hospital duration of stay among patients undergoing amputation" @default.
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• W2151030992 doi "https://doi.org/10.1016/j.surg.2015.11.009" @default.
• W2151030992 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26715440" @default.
• W2151030992 hasPublicationYear "2016" @default.
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