FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2151141383> ?p ?o ?g. }

• W2151141383 endingPage "712" @default.
• W2151141383 startingPage "703" @default.
• W2151141383 abstract "To sense numerous odorants and chemicals, animals have evolved a large number of olfactory receptor genes (Olfrs) in their genome. In particular, the house mouse has ∼1,100 genes in the Olfr gene family. This makes the mouse a good model organism to study Olfr genes and olfaction-related genes. To date, whether male and female mice possess the same ability in detecting environmental odorants is still unknown. Using the next generation sequencing technology (paired-end mRNA-seq), we detected 1,088 expressed Olfr genes in both male and female olfactory epithelium. We found that not only Olfr genes but also odorant-binding protein (Obp) genes have evolved rapidly in the mouse lineage. Interestingly, Olfr genes tend to express at a higher level in males than in females, whereas the Obp genes clustered on the X chromosome show the opposite trend. These observations may imply a more efficient odorant-transporting system in females, whereas a more active Olfr gene expressing system in males. In addition, we detected the expression of two genes encoding major urinary proteins, which have been proposed to bind and transport pheromones or act as pheromones in mouse urine. This observation suggests a role of main olfactory system (MOS) in pheromone detection, contrary to the view that only accessory olfactory system (AOS) is involved in pheromone detection. This study suggests the sexual differences in detecting environmental odorants in MOS and demonstrates that mRNA-seq provides a powerful tool for detecting genes with low expression levels and with high sequence similarities." @default.
• W2151141383 created "2016-06-24" @default.
• W2151141383 creator A5016381994 @default.
• W2151141383 creator A5024672546 @default.
• W2151141383 creator A5043019551 @default.
• W2151141383 creator A5048295168 @default.
• W2151141383 creator A5049358254 @default.
• W2151141383 creator A5079779805 @default.
• W2151141383 creator A5081055006 @default.
• W2151141383 date "2012-01-01" @default.
• W2151141383 modified "2023-09-25" @default.
• W2151141383 title "Transcriptomes of Mouse Olfactory Epithelium Reveal Sexual Differences in Odorant Detection" @default.
• W2151141383 cites W1509504005 @default.
• W2151141383 cites W1913751214 @default.
• W2151141383 cites W1971544693 @default.
• W2151141383 cites W1972628110 @default.
• W2151141383 cites W1978197873 @default.
• W2151141383 cites W1983646382 @default.
• W2151141383 cites W1988182516 @default.
• W2151141383 cites W1990487857 @default.
• W2151141383 cites W1994263655 @default.
• W2151141383 cites W1998837653 @default.
• W2151141383 cites W2002141216 @default.
• W2151141383 cites W2006134437 @default.
• W2151141383 cites W2007507157 @default.
• W2151141383 cites W2010357255 @default.
• W2151141383 cites W2022927508 @default.
• W2151141383 cites W2023313292 @default.
• W2151141383 cites W2023848419 @default.
• W2151141383 cites W2028190503 @default.
• W2151141383 cites W2033693803 @default.
• W2151141383 cites W2038438679 @default.
• W2151141383 cites W2054755820 @default.
• W2151141383 cites W2061793455 @default.
• W2151141383 cites W2061985556 @default.
• W2151141383 cites W2075581930 @default.
• W2151141383 cites W2077520409 @default.
• W2151141383 cites W2083487562 @default.
• W2151141383 cites W2085922872 @default.
• W2151141383 cites W2097065948 @default.
• W2151141383 cites W2098298179 @default.
• W2151141383 cites W2104171953 @default.
• W2151141383 cites W2108234281 @default.
• W2151141383 cites W2122533323 @default.
• W2151141383 cites W2124388496 @default.
• W2151141383 cites W2124473413 @default.
• W2151141383 cites W2125469896 @default.
• W2151141383 cites W2132632499 @default.
• W2151141383 cites W2133045453 @default.
• W2151141383 cites W2138478252 @default.
• W2151141383 cites W2141458291 @default.
• W2151141383 cites W2142108845 @default.
• W2151141383 cites W2144012199 @default.
• W2151141383 cites W2167499328 @default.
• W2151141383 cites W4234821777 @default.
• W2151141383 doi "https://doi.org/10.1093/gbe/evs039" @default.
• W2151141383 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3381674" @default.
• W2151141383 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22511034" @default.
• W2151141383 hasPublicationYear "2012" @default.
• W2151141383 type Work @default.
• W2151141383 sameAs 2151141383 @default.
• W2151141383 citedByCount "39" @default.
• W2151141383 countsByYear W21511413832013 @default.
• W2151141383 countsByYear W21511413832014 @default.
• W2151141383 countsByYear W21511413832015 @default.
• W2151141383 countsByYear W21511413832016 @default.
• W2151141383 countsByYear W21511413832017 @default.
• W2151141383 countsByYear W21511413832018 @default.
• W2151141383 countsByYear W21511413832019 @default.
• W2151141383 countsByYear W21511413832020 @default.
• W2151141383 countsByYear W21511413832021 @default.
• W2151141383 countsByYear W21511413832022 @default.
• W2151141383 countsByYear W21511413832023 @default.
• W2151141383 crossrefType "journal-article" @default.
• W2151141383 hasAuthorship W2151141383A5016381994 @default.
• W2151141383 hasAuthorship W2151141383A5024672546 @default.
• W2151141383 hasAuthorship W2151141383A5043019551 @default.
• W2151141383 hasAuthorship W2151141383A5048295168 @default.
• W2151141383 hasAuthorship W2151141383A5049358254 @default.
• W2151141383 hasAuthorship W2151141383A5079779805 @default.
• W2151141383 hasAuthorship W2151141383A5081055006 @default.
• W2151141383 hasBestOaLocation W21511413831 @default.
• W2151141383 hasConcept C104317684 @default.
• W2151141383 hasConcept C150194340 @default.
• W2151141383 hasConcept C158471640 @default.
• W2151141383 hasConcept C162317418 @default.
• W2151141383 hasConcept C163214680 @default.
• W2151141383 hasConcept C169760540 @default.
• W2151141383 hasConcept C170493617 @default.
• W2151141383 hasConcept C201792869 @default.
• W2151141383 hasConcept C2777328355 @default.
• W2151141383 hasConcept C2779404012 @default.
• W2151141383 hasConcept C2779980732 @default.
• W2151141383 hasConcept C2780187430 @default.
• W2151141383 hasConcept C54355233 @default.
• W2151141383 hasConcept C5911399 @default.
• W2151141383 hasConcept C64778439 @default.
• W2151141383 hasConcept C86803240 @default.

• next