FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2151282303> ?p ?o ?g. }

• W2151282303 endingPage "1502" @default.
• W2151282303 startingPage "1496" @default.
• W2151282303 abstract "Primary small-bowel adenocarcinoma is uncommon. There are few large studies that have evaluated the prognostic impact of clinical and pathologic parameters. The purpose of this study was to perform a comprehensive analysis of the Cleveland Clinic experience with small-bowel adenocarcinoma, with emphasis on histopathologic parameters as prognostic indicators.Thirty-seven cases of primary small-bowel adenocarcinomas resected at the Cleveland Clinic between 1978 and 1999 were retrospectively studied. Metastatic tumors and those arising from the biliary system were excluded from analysis. Clinical and pathologic data were recorded and their impact on prognosis was evaluated by either Kaplan-Meier or Cox proportional hazards analysis.The cohort included 25 males, and the age range was 24 to 82 (mean, 56) years. Tumor location was duodenum (18), jejunum (10), ileum (2), and site not specified (7). Patients most frequently presented with abdominal pain (48 percent), anemia (39 percent) and small-bowel obstruction (33 percent). Underlying conditions included Crohn's disease (4) and familial adenomatous polyposis (2). Overall survival was 52 and 47 percent at 5 and 10 years, respectively, with a mean follow-up of 50.5 (range, 0.5-184) months for all patients. Features found to be negative prognostic factors for survival were positive surgical margins (P < 0.001), extramural venous spread (P < 0.001), lymph node metastases (P = 0.038), poor tumor differentiation (P = 0.015), depth of tumor invasion (P = 0.023), and history of Crohn's disease (P < 0.001). Age, gender, tumor size, growth pattern, lymphocytic host response, and adjuvant therapy did not affect survival.Pathologic features, including positive surgical margins, extramural venous spread, positive lymph nodes, poor tumor differentiation, depth of tumor invasion, and history of Crohn's disease, are of major prognostic significance in small-bowel adenocarcinoma. Although many of these prognostic features are similar to the ones used for colorectal adenocarcinoma, they are easily applicable and reproducible for small-bowel adenocarcinomas. This is important considering the often dismal prognosis of small-bowel adenocarcinoma." @default.
• W2151282303 created "2016-06-24" @default.
• W2151282303 creator A5026198545 @default.
• W2151282303 creator A5035251468 @default.
• W2151282303 creator A5036339560 @default.
• W2151282303 creator A5042319997 @default.
• W2151282303 creator A5046052708 @default.
• W2151282303 date "2002-11-01" @default.
• W2151282303 modified "2023-09-23" @default.
• W2151282303 title "Adenocarcinoma of the Small Bowel" @default.
• W2151282303 cites W1594306308 @default.
• W2151282303 cites W1893440025 @default.
• W2151282303 cites W1963838055 @default.
• W2151282303 cites W1979213414 @default.
• W2151282303 cites W1982200901 @default.
• W2151282303 cites W1998020091 @default.
• W2151282303 cites W2001825099 @default.
• W2151282303 cites W2009937899 @default.
• W2151282303 cites W2014207760 @default.
• W2151282303 cites W2030329272 @default.
• W2151282303 cites W2035303769 @default.
• W2151282303 cites W2037223925 @default.
• W2151282303 cites W2037336401 @default.
• W2151282303 cites W2054059095 @default.
• W2151282303 cites W2076420760 @default.
• W2151282303 cites W2086688639 @default.
• W2151282303 cites W2109014603 @default.
• W2151282303 cites W2117293432 @default.
• W2151282303 cites W2141701961 @default.
• W2151282303 cites W2159714090 @default.
• W2151282303 cites W2326275783 @default.
• W2151282303 doi "https://doi.org/10.1007/s10350-004-6457-9" @default.
• W2151282303 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12432298" @default.
• W2151282303 hasPublicationYear "2002" @default.
• W2151282303 type Work @default.
• W2151282303 sameAs 2151282303 @default.
• W2151282303 citedByCount "101" @default.
• W2151282303 countsByYear W21512823032012 @default.
• W2151282303 countsByYear W21512823032013 @default.
• W2151282303 countsByYear W21512823032014 @default.
• W2151282303 countsByYear W21512823032015 @default.
• W2151282303 countsByYear W21512823032016 @default.
• W2151282303 countsByYear W21512823032017 @default.
• W2151282303 countsByYear W21512823032018 @default.
• W2151282303 countsByYear W21512823032019 @default.
• W2151282303 countsByYear W21512823032020 @default.
• W2151282303 countsByYear W21512823032021 @default.
• W2151282303 countsByYear W21512823032022 @default.
• W2151282303 countsByYear W21512823032023 @default.
• W2151282303 crossrefType "journal-article" @default.
• W2151282303 hasAuthorship W2151282303A5026198545 @default.
• W2151282303 hasAuthorship W2151282303A5035251468 @default.
• W2151282303 hasAuthorship W2151282303A5036339560 @default.
• W2151282303 hasAuthorship W2151282303A5042319997 @default.
• W2151282303 hasAuthorship W2151282303A5046052708 @default.
• W2151282303 hasConcept C121608353 @default.
• W2151282303 hasConcept C126322002 @default.
• W2151282303 hasConcept C2780140570 @default.
• W2151282303 hasConcept C2781182431 @default.
• W2151282303 hasConcept C50382708 @default.
• W2151282303 hasConcept C71924100 @default.
• W2151282303 hasConcept C90924648 @default.
• W2151282303 hasConceptScore W2151282303C121608353 @default.
• W2151282303 hasConceptScore W2151282303C126322002 @default.
• W2151282303 hasConceptScore W2151282303C2780140570 @default.
• W2151282303 hasConceptScore W2151282303C2781182431 @default.
• W2151282303 hasConceptScore W2151282303C50382708 @default.
• W2151282303 hasConceptScore W2151282303C71924100 @default.
• W2151282303 hasConceptScore W2151282303C90924648 @default.
• W2151282303 hasIssue "11" @default.
• W2151282303 hasLocation W21512823031 @default.
• W2151282303 hasLocation W21512823032 @default.
• W2151282303 hasOpenAccess W2151282303 @default.
• W2151282303 hasPrimaryLocation W21512823031 @default.
• W2151282303 hasRelatedWork W1966157439 @default.
• W2151282303 hasRelatedWork W1978494252 @default.
• W2151282303 hasRelatedWork W1997265056 @default.
• W2151282303 hasRelatedWork W2012046105 @default.
• W2151282303 hasRelatedWork W2120555548 @default.
• W2151282303 hasRelatedWork W2554436595 @default.
• W2151282303 hasRelatedWork W2996484176 @default.
• W2151282303 hasRelatedWork W3088504450 @default.
• W2151282303 hasRelatedWork W3165455020 @default.
• W2151282303 hasRelatedWork W3169097396 @default.
• W2151282303 hasVolume "45" @default.
• W2151282303 isParatext "false" @default.
• W2151282303 isRetracted "false" @default.
• W2151282303 magId "2151282303" @default.
• W2151282303 workType "article" @default.