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• W2151293397 startingPage "463" @default.
• W2151293397 abstract "The authors studied the distribution of met-enkephalin, α-endorphin, β-endorphin and LHRH within the central nervous system of rats by the indirect immunofluorescent technique, and observed α-endorphin-like immuoreactivity in the median eminence adjoining the portal vein as nerve terminals of dot-like immunofluorescence. This finding deserves special attention since α-endorphin has been considered physiologically inactive. Nerve terminals of α-endorphin-, β-endorphin- and met-enkephalin-like immunoreactivities were immunohistochemically confirmed in the medial hypothalamus. These results positively suggested that this area was playing comprehensive roles in physiological functions of the hypothalamo-pituitary system.To visualize neuropeptide-containing nerve cell bodies, we applied the immunofluorescent technique on various neuropeptides to intraventricularly colchicine injected rats. Some LHRH and met-enkephalin containing nerve cell bodies were observed without colchicine, though. All of substance P-, LHRH- and met-nekephalin-positive nerve cell bodies were visualized in the ventromedial hypothalamic nucleus, substance P- and β-endorphin positive nerve cell bodies in the arcuate nucleus, substance P-positive ones in the posterior hypothalamic nucleus and met-enkephalin-positive ones in the dorsomedial hypothalamic nucleus. Besides, substance P-containing and metenkephalin-containing nerve cell bodies were coexisting in the mesencephalic central gray matter. α-Endorphin-containing nerve cell bodies were also noticed in the caudate nucleus.In addition, calcitonin-like immunoreactive cell bodies were observed in the anterior lobe of the pituitary body." @default.
• W2151293397 created "2016-06-24" @default.
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• W2151293397 date "1980-01-01" @default.
• W2151293397 modified "2023-09-23" @default.
• W2151293397 title "IMMUNOHISTOCHEMICAL DISTRIBUTION OF NEUROPEPTIDES IN THE RAT CENTRAL NERVOUS SYSTEM" @default.
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• W2151293397 doi "https://doi.org/10.1267/ahc.13.463" @default.
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