FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2151314729> ?p ?o ?g. }

• W2151314729 endingPage "811" @default.
• W2151314729 startingPage "803" @default.
• W2151314729 abstract "Helicobacter pylori is a human gastric pathogen associated with gastric and duodenal ulcers as well as specific gastric cancers. H. pylori infects approximately 50% of the world's population, and infections can persist throughout the lifetime of the host. Motility and chemotaxis have been shown to be important in the infection process of H. pylori. We sought to address the specific roles of chemotaxis in infection of a mouse model system. We found that mutants lacking cheW, cheA, or cheY are all nonchemotactic and infect FVB/N mice with an attenuated phenotype after 2 weeks of infection. If infections proceeded for 6 months, however, this attenuation disappeared. Histological and culture analysis revealed that nonchemotactic mutants were found only in the corpus of the stomach, while the wild type occupied both the corpus and the antrum. Further analysis showed that nonchemotactic H. pylori isolates had an increased 50% infectious dose and were greatly outcompeted when coinfected with the wild type. If nonchemotactic mutants were allowed to establish an infection, subsequent infection with the wild type partially displaced the nonchemotactic mutants, indicating a role for chemotaxis in maintenance of infection. The data presented here support four roles for chemotaxis in H. pylori mouse infections: (i) establishing infection, (ii) achieving high-level infection, (iii) maintaining an infection when there are competing H. pylori present, and (iv) colonizing all regions of the stomach." @default.
• W2151314729 created "2016-06-24" @default.
• W2151314729 creator A5016763778 @default.
• W2151314729 creator A5027872414 @default.
• W2151314729 creator A5041650561 @default.
• W2151314729 creator A5091102928 @default.
• W2151314729 date "2005-02-01" @default.
• W2151314729 modified "2023-09-27" @default.
• W2151314729 title "Chemotaxis Plays Multiple Roles during <i>Helicobacter pylori</i> Animal Infection" @default.
• W2151314729 cites W1593075457 @default.
• W2151314729 cites W1874234489 @default.
• W2151314729 cites W1914199460 @default.
• W2151314729 cites W1971976758 @default.
• W2151314729 cites W1973232347 @default.
• W2151314729 cites W1988716463 @default.
• W2151314729 cites W1991447989 @default.
• W2151314729 cites W1994029249 @default.
• W2151314729 cites W2016299826 @default.
• W2151314729 cites W2029851838 @default.
• W2151314729 cites W2036582645 @default.
• W2151314729 cites W2047043794 @default.
• W2151314729 cites W2060298161 @default.
• W2151314729 cites W2062001398 @default.
• W2151314729 cites W2069378448 @default.
• W2151314729 cites W2071502163 @default.
• W2151314729 cites W2099560419 @default.
• W2151314729 cites W2110132014 @default.
• W2151314729 cites W2113739192 @default.
• W2151314729 cites W2116473184 @default.
• W2151314729 cites W2119563832 @default.
• W2151314729 cites W2126952238 @default.
• W2151314729 cites W2129012692 @default.
• W2151314729 cites W2129221594 @default.
• W2151314729 cites W2133923782 @default.
• W2151314729 cites W2135668251 @default.
• W2151314729 cites W2140493600 @default.
• W2151314729 cites W2141827029 @default.
• W2151314729 cites W2143704499 @default.
• W2151314729 cites W2145845306 @default.
• W2151314729 cites W2147512361 @default.
• W2151314729 cites W2150314694 @default.
• W2151314729 cites W2165296767 @default.
• W2151314729 cites W2166801001 @default.
• W2151314729 cites W2427501075 @default.
• W2151314729 cites W4248277133 @default.
• W2151314729 doi "https://doi.org/10.1128/iai.73.2.803-811.2005" @default.
• W2151314729 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/547030" @default.
• W2151314729 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15664919" @default.
• W2151314729 hasPublicationYear "2005" @default.
• W2151314729 type Work @default.
• W2151314729 sameAs 2151314729 @default.
• W2151314729 citedByCount "141" @default.
• W2151314729 countsByYear W21513147292012 @default.
• W2151314729 countsByYear W21513147292013 @default.
• W2151314729 countsByYear W21513147292014 @default.
• W2151314729 countsByYear W21513147292015 @default.
• W2151314729 countsByYear W21513147292016 @default.
• W2151314729 countsByYear W21513147292017 @default.
• W2151314729 countsByYear W21513147292018 @default.
• W2151314729 countsByYear W21513147292019 @default.
• W2151314729 countsByYear W21513147292020 @default.
• W2151314729 countsByYear W21513147292021 @default.
• W2151314729 countsByYear W21513147292022 @default.
• W2151314729 countsByYear W21513147292023 @default.
• W2151314729 crossrefType "journal-article" @default.
• W2151314729 hasAuthorship W2151314729A5016763778 @default.
• W2151314729 hasAuthorship W2151314729A5027872414 @default.
• W2151314729 hasAuthorship W2151314729A5041650561 @default.
• W2151314729 hasAuthorship W2151314729A5091102928 @default.
• W2151314729 hasBestOaLocation W21513147292 @default.
• W2151314729 hasConcept C104317684 @default.
• W2151314729 hasConcept C127716648 @default.
• W2151314729 hasConcept C131253125 @default.
• W2151314729 hasConcept C143065580 @default.
• W2151314729 hasConcept C170493617 @default.
• W2151314729 hasConcept C203014093 @default.
• W2151314729 hasConcept C2776409635 @default.
• W2151314729 hasConcept C2776460866 @default.
• W2151314729 hasConcept C2779422922 @default.
• W2151314729 hasConcept C2908647359 @default.
• W2151314729 hasConcept C54166955 @default.
• W2151314729 hasConcept C54355233 @default.
• W2151314729 hasConcept C55493867 @default.
• W2151314729 hasConcept C58207958 @default.
• W2151314729 hasConcept C71924100 @default.
• W2151314729 hasConcept C86803240 @default.
• W2151314729 hasConcept C89423630 @default.
• W2151314729 hasConcept C99454951 @default.
• W2151314729 hasConceptScore W2151314729C104317684 @default.
• W2151314729 hasConceptScore W2151314729C127716648 @default.
• W2151314729 hasConceptScore W2151314729C131253125 @default.
• W2151314729 hasConceptScore W2151314729C143065580 @default.
• W2151314729 hasConceptScore W2151314729C170493617 @default.
• W2151314729 hasConceptScore W2151314729C203014093 @default.
• W2151314729 hasConceptScore W2151314729C2776409635 @default.
• W2151314729 hasConceptScore W2151314729C2776460866 @default.
• W2151314729 hasConceptScore W2151314729C2779422922 @default.
• W2151314729 hasConceptScore W2151314729C2908647359 @default.

• next