Matches in SemOpenAlex for { <https://semopenalex.org/work/W2151371344> ?p ?o ?g. }
- W2151371344 endingPage "462" @default.
- W2151371344 startingPage "453" @default.
- W2151371344 abstract "TLS (also known as FUS) is an RNA-binding protein that contributes the N-terminal half of fusion oncoproteins implicated in the development of human liposarcomas and leukemias. Here we report that male mice homozygous for an induced mutation in TLS are sterile with a marked increase in the number of unpaired and mispaired chromosomal axes in pre-meiotic spermatocytes. Nuclear extracts from TLS(-/-) testes lack an activity capable of promoting pairing between homologous DNA sequences in vitro, and TLS(-/-) mice and embryonic fibroblasts exhibit increased sensitivity to ionizing irradiation. These results are consistent with a role for TLS in homologous DNA pairing and recombination." @default.
- W2151371344 created "2016-06-24" @default.
- W2151371344 creator A5003442430 @default.
- W2151371344 creator A5005230545 @default.
- W2151371344 creator A5006017994 @default.
- W2151371344 creator A5006055957 @default.
- W2151371344 creator A5023915574 @default.
- W2151371344 creator A5042572217 @default.
- W2151371344 creator A5055162786 @default.
- W2151371344 creator A5067379327 @default.
- W2151371344 creator A5077934127 @default.
- W2151371344 creator A5078070753 @default.
- W2151371344 creator A5078348186 @default.
- W2151371344 date "2000-02-01" @default.
- W2151371344 modified "2023-10-12" @default.
- W2151371344 title "Male sterility and enhanced radiation sensitivity in TLS-/- mice" @default.
- W2151371344 cites W122421387 @default.
- W2151371344 cites W1480699894 @default.
- W2151371344 cites W1645470992 @default.
- W2151371344 cites W1754465676 @default.
- W2151371344 cites W1789215739 @default.
- W2151371344 cites W188279554 @default.
- W2151371344 cites W1960694079 @default.
- W2151371344 cites W1966092175 @default.
- W2151371344 cites W1976936698 @default.
- W2151371344 cites W1977694859 @default.
- W2151371344 cites W1983713993 @default.
- W2151371344 cites W1983976485 @default.
- W2151371344 cites W1995891481 @default.
- W2151371344 cites W1996121905 @default.
- W2151371344 cites W2002555966 @default.
- W2151371344 cites W2004497836 @default.
- W2151371344 cites W2004822307 @default.
- W2151371344 cites W2018609920 @default.
- W2151371344 cites W2024116210 @default.
- W2151371344 cites W2046633261 @default.
- W2151371344 cites W2047354263 @default.
- W2151371344 cites W2059707627 @default.
- W2151371344 cites W2065387333 @default.
- W2151371344 cites W2069351898 @default.
- W2151371344 cites W2074058827 @default.
- W2151371344 cites W2075185862 @default.
- W2151371344 cites W2093528151 @default.
- W2151371344 cites W2113902412 @default.
- W2151371344 cites W2115670698 @default.
- W2151371344 cites W2117936052 @default.
- W2151371344 cites W2147685192 @default.
- W2151371344 cites W2149190454 @default.
- W2151371344 cites W2162824445 @default.
- W2151371344 cites W2164245070 @default.
- W2151371344 cites W2164627733 @default.
- W2151371344 cites W2286297234 @default.
- W2151371344 cites W2332948343 @default.
- W2151371344 cites W2334981267 @default.
- W2151371344 cites W61004016 @default.
- W2151371344 cites W987729868 @default.
- W2151371344 doi "https://doi.org/10.1093/emboj/19.3.453" @default.
- W2151371344 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/305582" @default.
- W2151371344 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10654943" @default.
- W2151371344 hasPublicationYear "2000" @default.
- W2151371344 type Work @default.
- W2151371344 sameAs 2151371344 @default.
- W2151371344 citedByCount "211" @default.
- W2151371344 countsByYear W21513713442012 @default.
- W2151371344 countsByYear W21513713442013 @default.
- W2151371344 countsByYear W21513713442014 @default.
- W2151371344 countsByYear W21513713442015 @default.
- W2151371344 countsByYear W21513713442016 @default.
- W2151371344 countsByYear W21513713442017 @default.
- W2151371344 countsByYear W21513713442018 @default.
- W2151371344 countsByYear W21513713442019 @default.
- W2151371344 countsByYear W21513713442020 @default.
- W2151371344 countsByYear W21513713442021 @default.
- W2151371344 countsByYear W21513713442022 @default.
- W2151371344 countsByYear W21513713442023 @default.
- W2151371344 crossrefType "journal-article" @default.
- W2151371344 hasAuthorship W2151371344A5003442430 @default.
- W2151371344 hasAuthorship W2151371344A5005230545 @default.
- W2151371344 hasAuthorship W2151371344A5006017994 @default.
- W2151371344 hasAuthorship W2151371344A5006055957 @default.
- W2151371344 hasAuthorship W2151371344A5023915574 @default.
- W2151371344 hasAuthorship W2151371344A5042572217 @default.
- W2151371344 hasAuthorship W2151371344A5055162786 @default.
- W2151371344 hasAuthorship W2151371344A5067379327 @default.
- W2151371344 hasAuthorship W2151371344A5077934127 @default.
- W2151371344 hasAuthorship W2151371344A5078070753 @default.
- W2151371344 hasAuthorship W2151371344A5078348186 @default.
- W2151371344 hasBestOaLocation W21513713441 @default.
- W2151371344 hasConcept C102744134 @default.
- W2151371344 hasConcept C104317684 @default.
- W2151371344 hasConcept C134935766 @default.
- W2151371344 hasConcept C148196450 @default.
- W2151371344 hasConcept C153911025 @default.
- W2151371344 hasConcept C2776687438 @default.
- W2151371344 hasConcept C501734568 @default.
- W2151371344 hasConcept C54355233 @default.
- W2151371344 hasConcept C552990157 @default.
- W2151371344 hasConcept C64894306 @default.